Acute Safety and Efficacy of a Novel Multipolar Irrigated Radiofrequency Ablation Catheter for Pulmonary Vein Isolation

Deneke, Thomas; Schade, Anja; Müller, Patrick; Schmitt, Rainer; Christopoulos, Georgios; Krug, Joachim; Szőllősi, G.-Y.; Mügge, Andreas; Kerber, Sebastian; Nentwich, Karin

doi:10.1111/jce.12316

Cited by 63 publications

(74 citation statements)

References 19 publications

(20 reference statements)

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“…Several one-shot catheters have been developed, including balloon-based technology and multielectrode ablation catheters [4][5][6][7]. At present, there is no data analyzing the influence of PV anatomy on the clinical efficacy of the irrigated multielectrodes ablation catheter (nMARQ TM ) for PV isolation in patients with AF.…”

Section: Introductionmentioning

confidence: 99%

Effect of left atrial volume and pulmonary vein anatomy on outcome of nMARQ™ catheter ablation of paroxysmal atrial fibrillation

Stabile

Anselmino

Soldati

et al. 2016

J Interv Card Electrophysiol

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Results. Mean LA volume was 75±40 ml. A normal anatomy (4 PVs) was documented in 40 (53%) patients, an abnormal anatomy (common truncus or accessory PVs) in 35 patients. Mean procedural and fluoroscopy times were 94 ± 55 minutes and 8 ± 5 minutes, respectively, without significant differences among patients with normal or abnormal anatomy (92±45 min vs 95±64 min, p=0.85 and 6±3 min vs 8±4 min, p=0.65, respectively).Mean ablation time was 14 3 min, 99% of the targeted veins were isolated with a mean of 23±5 RF pulses per patient. After a mean follow-up of 17±8 months, 23(31%) patients had an atrial arrhythmia recurrence. Neither LA volume nor PV anatomy were predictors of outcome.Conclusions. LA volume and PV anatomy did not effect procedural data and outcome in patients who underwent PV isolation by an open-irrigated mapping and RF decapolar ablation catheter.3

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Section: Introductionmentioning

confidence: 99%

Effect of left atrial volume and pulmonary vein anatomy on outcome of nMARQ™ catheter ablation of paroxysmal atrial fibrillation

Stabile

Anselmino

Soldati

et al. 2016

J Interv Card Electrophysiol

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“…Touch-up ablation using a 3.5-mm tip open-irrigated catheter was needed only for 1 patient (2 veins) as reported by Scaglione et al [7] but not in any of the case reported by Shin et al [5]. One left superior PV and 1 left inferior PV could not be isolated using the nMARQ TM catheter as reported by Deneke et al [8]. However, is not mentioned if touch up ablation was performed.…”

Section: Discussionmentioning

confidence: 81%

“…In all cases except one left inferior PV, confirmation of PVI was achieved using only the nMARQ TM catheter as reported by deneke et al [8]. However, the concordance between the nMARQ TM signals…”

Section: Discussionmentioning

confidence: 92%

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Acute and Mid-Term Results after Pulmonary Veins Isolation Using a Novel Circular Irrigated Multielectrode Mapping and Ablation Catheter (nMARQ)

Marai¹,

Suleiman²,

Lessick³

et al. 2016

WJCD

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Background: Pulmonary vein isolation (PVI) is the cornerstone of atrial fibrillation (AF) ablation in both paroxysmal and persistent AF. However, this procedure is still challenging and time consuming. Objective: The aim of this study was to present our approach for PVI using a novel circular irrigated multielectrode mapping and ablation catheter (nMARQ TM ) and to present acute and mid-term results. Methods:The study included 31 consecutive patients with symptomatic AF (4 had persistent and 27 had paroxysmal AF) who underwent PVI using the nMARQ TM catheter. Circular ablation was guided by CT image integrated into fast anatomical map and by intra cardiac echo. Isolation of pulmonary veins was identified using the nMARQ TM catheter if it was possible to advance it into the veins, otherwise Lasso catheter was used. Patients were followed up to 20 months. Results: PVI was achieved in 119 (98%) out of 121 pulmonary veins identified, and final PVI was obtained in 30 (97%) out of 31 patients. Lasso catheter was needed for PVI confirmation in 16 (52%) patients. Touch up ablation using standard catheter guided by Lasso catheter was needed in 4 (13%) patients. Pericardial tamponade occurred in 1 patient who was treated with pericardiocentesis. No other major complications were detected. During follow-up (mean 15.9 ± 3.6 months, range 9 -20 months), 4 (13%) patients had recurrence of atrial tachyarrhythmia. Conclusion: PVI using the novel nMARQ TM catheter is safe with good acute and mid-term efficacy. Long term follow up trials are needed.

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“…Preliminary reports raised concerns about the safety of the nMARQ TM catheter. Deneke et al (7,13) reported one esophago-pericardial fistula, a high incidence of mild thermal esophageal lesions, and an incidence of silent cerebral lesions higher than single-tip irrigated RF. However Scaglione et al (12), using a specific and cautious procedural workflow, observed the complete absence of periprocedural silent cerebral ischemia.…”

Section: Discussionmentioning

confidence: 99%

Safety and efficacy of pulmonary vein isolation using a circular, open-irrigated mapping and ablation catheter: A multicenter registry

et al. 2015

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Acute Safety and Efficacy of a Novel Multipolar Irrigated Radiofrequency Ablation Catheter for Pulmonary Vein Isolation

Cited by 63 publications

References 19 publications

Effect of left atrial volume and pulmonary vein anatomy on outcome of nMARQ™ catheter ablation of paroxysmal atrial fibrillation

Effect of left atrial volume and pulmonary vein anatomy on outcome of nMARQ™ catheter ablation of paroxysmal atrial fibrillation

Acute and Mid-Term Results after Pulmonary Veins Isolation Using a Novel Circular Irrigated Multielectrode Mapping and Ablation Catheter (nMARQ)

Safety and efficacy of pulmonary vein isolation using a circular, open-irrigated mapping and ablation catheter: A multicenter registry

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