Acute Right Atrial Strain*

Asad, Navaid; Johnson, Vanessa M.P.; Spodick, David H.

doi:10.1378/chest.124.2.560

Cited by 20 publications

(3 citation statements)

References 4 publications

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“…On the other hand, Asad et al showed a rapid reversal of P wave characteristics responding to therapy in patients with Chronic Obstructive Lung Disease [32]. Furthermore, Carilli et al showed in a retrospective study the predictive value of P-wave amplitude and axis in estimating the severity of nonasthmatic airway obstructive disease in the quiescent state and they demonstrated a good correlation of P wave amplitude and axis with FEV1/FVC and the residual volume/total lung capacity in a continuous regression equation [33].…”

Section: Discussionmentioning

confidence: 99%

P Wave Analysis in Patients with Sarcoidosis

Gialafos¹,

Perros²,

Rapti³

et al. 2013

IJCM

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Introduction: Atrial arrhythmias in patients with sarcoidosis (Sar) are not unusual and can occur due to either atrial myocardial fibrosis and/or due to autonomic nervous system imbalance. Electrocardiographic markers (ECG), like maximum and minimum P wave duration and P wave dispersion {Pdis = Pmax ﹣Pmin} reflect atrial depolarization inhomogeneity and can indicate patients prone to develop atrial arrhythmias while standard deviation of RR interval (SDNN) is an index of heart rate variability, reflecting autonomic nervous system (ANS) activity. Methods: 90 patients with sarcoidosis (41 males/49 females) enrolled in this multicenter prospective study underwent digital electrocardiography, echocardiography and pulmonary function tests (PFTs). Diastolic and systolic indices of right and left ventricle were measured echocardiographically including Doppler parameters while Pmax, Pmin, Pdis and SDNN were measured in a 5-minute duration digital electrocardiogram. All consecutive patients were compared to 65 healthy volunteers (30 males/35 females). Results: Although heart rate and the echocardiographic indices were similar among the two groups, the electrocardiographic indices were significantly prolonged in the patient group compared to controls. Maximum P wave duration was correlated with SDNN (p < 0.05, r = ﹣0.272) and the age of the patients (p < 0.05, r = 0.219) while Pdis was correlated with SDNN (p < 0.001, r = 0.350) and the heart rate (p < 0.005, r = 0.323). Multivariate analysis showed that Pmax and Pdis were independently correlated with SDNN. Conclusion: P wave dispersion is signifi...

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Section: Discussionmentioning

confidence: 99%

P Wave Analysis in Patients with Sarcoidosis

Gialafos¹,

Perros²,

Rapti³

et al. 2013

IJCM

View full text Add to dashboard Cite

show abstract

“…The association of prolongation of P wave dispersion and right atrial enlargement (RAE) with COPD may explain the increased prevalence of atrial arrhythmias, such as atrial fibrillation and MAT [124, 125]. Increased P wave amplitude is present in 14% of patients presenting to the emergency department with AECOPD [126]. P wave amplitude decreases after acute treatment in patients admitted for AECOPD, possibly reflecting reduced right atrial strain [126].…”

Section: Markers Of Cardiac Disease In Aecopdmentioning

confidence: 99%

“…Increased P wave amplitude is present in 14% of patients presenting to the emergency department with AECOPD [126]. P wave amplitude decreases after acute treatment in patients admitted for AECOPD, possibly reflecting reduced right atrial strain [126]. …”

Section: Markers Of Cardiac Disease In Aecopdmentioning

confidence: 99%

Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Cardiovascular Links

Laratta

Eeden

2014

BioMed Research International

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Chronic obstructive pulmonary disease (COPD) is a chronic, progressive lung disease resulting from exposure to cigarette smoke, noxious gases, particulate matter, and air pollutants. COPD is exacerbated by acute inflammatory insults such as lung infections (viral and bacterial) and air pollutants which further accelerate the steady decline in lung function. The chronic inflammatory process in the lung contributes to the extrapulmonary manifestations of COPD which are predominantly cardiovascular in nature. Here we review the significant burden of cardiovascular disease in COPD and discuss the clinical and pathological links between acute exacerbations of COPD and cardiovascular disease.

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The Prognostic Importance of Isolated P‐Wave Abnormalities

Kaykha

Myers

Desser

et al. 2010

Clinical Cardiology

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Background: While certain P-Wave morphologies have been associated with abnormal atrial size and either pulmonary or cardiovascular (CV) disease, their relationship to mortality and specific cause of death has not been reported. Methods: Analyses were performed on the first digitally recorded electrocardiogram (ECG) on 43 903 patients at the Palo Alto Veterans Administration Medical Center since 1987. After appropriate exclusions, 40 020 patients remained. Using computerized algorithms, P-wave amplitude and duration in 12 leads as well as several standardized ECG interpretations were extracted. The main outcome measures were pulmonary and CV mortality. Results: During a mean follow-up of 6 years there were 3417 CV and 1213 pulmonary deaths. After adjusting for age and heart rate in a Cox regression model, P-wave amplitude in the inferior leads was the strongest predictor of pulmonary death (hazard ratio [HR]: 3.0, 95% confidence interval [CI]: 2.3-3.9, P < .0001 for an amplitude >2.5 mm), outperforming all other ECG criteria. The depth of P-wave inversion in leads V 1 or V 2 and P-wave duration were strong predictors of CV death (HR: 1.7, 95% CI: 1.5-2.0, P < 0.0001 for a P-wave inversion deeper than 1 mm), outperforming many previously established ECG predictors of CV death. Conclusions: P-wave amplitude in the inferior leads is the strongest independent predictor of pulmonary death while P-wave duration and the depth of P-wave inversion in leads V 1 or V 2 significantly predict CV death. These measurements can be obtained easily and should be considered as part of clinical risk stratification.

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Acute Right Atrial Strain*

Cited by 20 publications

References 4 publications

P Wave Analysis in Patients with Sarcoidosis

P Wave Analysis in Patients with Sarcoidosis

Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Cardiovascular Links

The Prognostic Importance of Isolated P‐Wave Abnormalities

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