Acute responses of the freshwater eel (Anguilla anguilla) to extracts of the corpuscles of stannius opposing the effects of stanniosomatiectomy

Kenyon, Christopher J.; Jones, I.Chester; Dixon, R.N.B.

doi:10.1016/0016-6480(80)90058-1

Cited by 17 publications

(4 citation statements)

References 20 publications

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“…Wendelaar Bonga, Department "f Zoology, University of Nijmegen, 6525 ED Nijmegen, The Neth erlands to the hormonal products released by the CS. Removal of the glands (stanniectomy) results in a distinct hypercalce mia (Fontaine 1964;Pang et al 1973;Wendelaar Bonga and Greven 1978;Fenwick and Wendelaar Bonga 1982), whereas injection of homogenates of the glands can reduce the hypercalcemia in stanniectomized Fish (Pang 1973;Pang et al 1973;Dubewar and Suryawanshi 1978;So and Fen wick 1977;Kenyon et al 1980) or induce hypocalcemia in intact fish (Pang and Pang 1974;Swarup and Srivastav 1982;Lafeber et al 1984). For some fish species, it has been reported that the CS become activated during gonadal maturation, most mark edly in female fish (Lopez 1969;Hiroi 1970;Subhedar and Rao 1979).…”

Section: Many Authors Have Attributed a Hypocalcemic Functionmentioning

confidence: 99%

Stannius corpuscles and plasma calcium levels during the reproductive cycle in the cichlid teleost fish, Oreochromis mossambicus

Urasa

Bonga

1985

Cell Tissue Res.

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The corpuscles of Stannius (CS) of the cichlid Oreochromis mossambicus (formerly Sarotherodon mossambicus) were studied in relation to sexual maturation and plasma calcium levels. After sexual maturation, the CS are enlarged in female fish, because of an increase in size and number of the type-1 cells. During the ovarian cycle, the size of the CS increases in parallel with the growth of the ovaries. Concurrently, plasma total calcium increases markedly until spawning. This increase is mainly accounted for by calcium bound to proteins (vitellogenins), but the ultrafiltrable calcium fraction is also slightly higher than in males. Ovariectomy is followed by a reduction in the size of the CS, mainly a result of involution of the type-1 cells, and by a reduction in plasma calcium to levels typical for males. Gonadectomy in males does not affect size or ultrastructure of the CS, or plasma calcium levels. Since the type-1 cells of the CS are the presumptive source of a hypocalcemic hormone, we conclude that activation of the CS during the female reproductive cycle is a response to elevated calcium levels that accompany ovarian maturation. We suggest that the CS respond in particular to the elevated ultrafiltrable or ionic calcium levels.

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Section: Many Authors Have Attributed a Hypocalcemic Functionmentioning

confidence: 99%

Stannius corpuscles and plasma calcium levels during the reproductive cycle in the cichlid teleost fish, Oreochromis mossambicus

Urasa

Bonga

1985

Cell Tissue Res.

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“…There is overwhelming evidence that type-1 cells of the CS contain a potent hypocalcaemic factor (reviewed by Wendelaar Bonga and Pang, 1986). Removal of the CS causes hypercalcaemia in all teleosts tested (Fontaine, 1964(Fontaine, , 1967Fenwick and Forster, 1972;Fenwick, 1974;Pang et al 1973;Schreibman and Pang, 1975;Kenyon et al 1980;Urasa and Wendelaar Bonga, 1987;Hanssen et al 1989). Further, the hypercalcaemia induced by stanniectomy is prevented by ectopic CS implants (Pang et al 1973;Schreibman and Pang, 1975) or reversed by injections of CS extracts (Kenyon et al 1980;Hanssen et al 1989).…”

Section: Introductionmentioning

confidence: 95%

“…Removal of the CS causes hypercalcaemia in all teleosts tested (Fontaine, 1964(Fontaine, , 1967Fenwick and Forster, 1972;Fenwick, 1974;Pang et al 1973;Schreibman and Pang, 1975;Kenyon et al 1980;Urasa and Wendelaar Bonga, 1987;Hanssen et al 1989). Further, the hypercalcaemia induced by stanniectomy is prevented by ectopic CS implants (Pang et al 1973;Schreibman and Pang, 1975) or reversed by injections of CS extracts (Kenyon et al 1980;Hanssen et al 1989). Injection of CS extracts also inhibits branchial (So and Fenwick, 1979;Lafeber et al 1988a) and whole-body (Lafeber et al 1988a;Wagner et al 1986Wagner et al , 1988a calcium uptake (J^?)…”

Section: Introductionmentioning

confidence: 99%

Depression Of Whole-Body Calcium Uptake During Acute Hypercalcaemia In American Eel, Anguilla Rostrata, is Mediated Exclusively by Corpuscles of Stannius

Perry

Seguin

Lafeber

et al. 1989

Journal of Experimental Biology

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1. The role of the corpuscles of Stannius (CS) in acute modulation of wholebody calcium influx (JinCa) in American eel, Anguilla rostrata, was investigated by (i) assessing the effects of stanniectomy on JinCa and plasma total calcium concentration ([Catot]), (ii) comparing the abilities of sham-operated and stanniectomized eels to reduce JinCa during artificially induced hypercalcaemia, and (iii) monitoring the effects of homologous hypocalcin (a 54×103Mr glycoprotein injection on JinCa 2. Stanniectomy (STX) caused a pronounced elevation of JinCa and hypercalcaemia measured 7 days after surgery. 3. When hypercalcaemia was induced by intra-arterial infusion of CaCl2, a treatment known to cause degranulation of the CS and the specific release of hypocalcin, JinCa was reduced significantly within 1 h in intact fish. NaCl infusion did not affect plasma [Catot] or JinCa in any group tested. 4. Stanniectomy prevented the reduction of JinCa associated with the hypercalcaemia induced by CaCl2 infusion. 5. Intra-arterial infusion of MgCl2 caused a significant elevation of plasma total magnesium concentration [Mgtot] but did not alter JinCa. 6. Intra-arterial infusion of hypocalcin (l8.5 nmolkg−1 body mass) into intact eels decreased JinCa to an extent similar to that seen following artificially induced hypercalcaemia. 7. We conclude that the rapid reduction of JinCa during experimental hypercalcaemia is mediated by hypocalcin released from the corpuscles of Stannius and suggest that calcitonin, another putative hypocalcaemic hormone, is not involved. The results are discussed with respect to the relative importance of hypocalcin and calcitonin as hypocalcaemic hormones in fish.

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“…Fontaine (1964) reported that removal of the corpuscles of Stannius (CSX), led to electrolyte imbalance in European freshwater eels (A. anguilla) including hypercalcemia, hypophosphatemia, hyperkalemia, and hyponatremia. Some or all of these changes in plasma and muscle electrolyte concentrations were observed subsequently in freshwater A. anguilla (Chan et al, 1967(Chan et al, , 1969Chester Jones et al, 1965;Kenyon et al, 1980), freshwater North American eels (A. rostrata) (Butler, 1969(Butler, , 1993(Butler, , 1999 and goldfish (Carassius auratus) (Ogawa, 1968) after CSX.…”

Section: Introductionmentioning

confidence: 97%

Response by the corpuscles of Stannius to hypotensive stimuli in three divergent ray-finned fishes (Amia calva, Anguilla rostrata, and Catastomus commersoni): cardiovascular and morphological changes

Butler

Zhang

Villadiego

et al. 2003

General and Comparative Endocrinology

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In accordance with their vital role in cardiovascular physiology () corpuscles of Stannius (CS) from two teleosts and an holostean species showed marked and consistent degranulation and exocytotic responses to hypotensive stimuli. In eels (Anguilla rostrata LeSueur) acute blood withdrawal (hypovolemic hypotension) was followed by a prompt decrease in cardiac output (CO) and dorsal aortic pressure (P(DA)), a compensatory tachycardic response and an increase in systemic vascular resistance (R(SYS)). Isovolemic hypotension induced by papaverine i.v., led to a similar, but more prolonged, decrease in P(DA) but the heart rate (HR) continued to accelerate, thereby counterbalancing the severe and persistent decrease in R(SYS). Both hypovolemic and isovolemic hypotension were followed by a significant depletion of cytoplasmic granules from eel CS even though plasma concentrations of Ca, Mg, Na(+), and K(+) were normal. In an ancient holostean fish, the bowfin, Amia calva and a generalized teleost fish, Catastomus commersoni, the number of cytoplasmic granules decreased by 39% and 54%, respectively, 120 min after the acute withdrawal of 8 ml kg bw(-1) of blood. These findings suggest that a primary role of the CS is to release cytoplasmic granules containing renin or isorenin into the blood circulation, in response to hypotension and/or hypovolemia.

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Acute responses of the freshwater eel (Anguilla anguilla) to extracts of the corpuscles of stannius opposing the effects of stanniosomatiectomy

Cited by 17 publications

References 20 publications

Stannius corpuscles and plasma calcium levels during the reproductive cycle in the cichlid teleost fish, Oreochromis mossambicus

Stannius corpuscles and plasma calcium levels during the reproductive cycle in the cichlid teleost fish, Oreochromis mossambicus

Depression Of Whole-Body Calcium Uptake During Acute Hypercalcaemia In American Eel, Anguilla Rostrata, is Mediated Exclusively by Corpuscles of Stannius

Response by the corpuscles of Stannius to hypotensive stimuli in three divergent ray-finned fishes (Amia calva, Anguilla rostrata, and Catastomus commersoni): cardiovascular and morphological changes

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