Acute Respiratory Failure Due to Chronic Tophaceous Gout With Laryngeal and Bronchial Involvement: An Unusual Complication

Tophaceous Gout Causing the Carpal Tunnel Syndrome and Flexor Digitorum Dysfunction: A Case Report

“…При этом известно, что депозиты моноурата натрия могут откладываться в любых суставах, в том числе в межпозвонковых дисках, а также во внутренних органах. Описаны случаи обнаружения тофусов в органах дыхательной системы, структурах глаза, ногтях, молочной железе, почках, печени, на клапанах сердца, в поджелудочной железе, кишечнике [9][10][11][12][13][14][15][16][17].…”

Auricular Multiple Tophi Presenting as Painful Bilateral Nodules: A Case Report and Literature Review

“…While uncommon, tophus deposition in the head and neck has been described in a number of sites outside of the ear. 6) However, a PubMed search yielded just a few articles specifically addressing ATs (Table 1). [1][2][3]5,[7][8][9][10][11][12][13][14] Interestingly, all of the patients were male.…”

“…Few cases of tophaceous deposits in the auricular helix, middle ear, larynx, cricoarytenoid joint as well as gouty arthritis of the temporomandibular and sternoclavicular joint have been reported in the literature. 1,[3][4][5][6] Infected tophi can cause pain and restrict joint movement. Tophi can be controlled via nonsteroidal anti-inflammatory drugs, steroids, and urate-lowering drugs (e.g., allopurinol, benzbromarone, probenecid, colchicine, pegloticase), surgical removal, or hemodialysis.…”

Atypical Infraglottic Lesion

“…8 Of the 20 reported cases in which subsite was identified, laryngeal gout was localized to the true vocal fold (7), 3,5,6,9,10 laryngeal ventricle (1), 3,6 subglottis (2), 3,4,6 thyroid cartilage (3), 6,11 arytenoid (1), 3,6 and cricoarytenoid joint (6). 3,6,12 Involvement of the true vocal fold typically presents with mild symptoms such as hoarseness or sore throat. 5,6,9 Cricoarytenoid joint involvement is often associated with pain and, if severe, can cause airway compromise.…”

“…5,6,9 Cricoarytenoid joint involvement is often associated with pain and, if severe, can cause airway compromise. 6,12 When the vocal folds are uninvolved, symptoms may be less specific or absent. 4,5 Gouty involvement should be considered in patients with systemic gout and unexplained laryngeal symptoms, and laryngoscopy should be performed.…”