Acute respiratory failure and short-term outcome after premature rupture of the membranes and oligohydramnios before 20 weeks of gestation

Rupture of membranes before the age of viability and birth after the age of viability: comparison of outcomes in a matched cohort study

“…Lindner et al, 12 in a retrospective matched cohort study of 19 infants, reported that PPROM before 20 weeks was associated with higher risk of mortality, CLD and air leak when compared with infants not exposed to PPROM. However, the differences were PPROM before age of viability and neonatal outcomes H Soylu et al not statistically significantly different due to lack of power in the study.…”

“…6 Perinatal survival was reported to be <20% when PPROM occurred at both <20 and between 20 and 23 weeks gestation. On one hand, improved survival has been reported in recent years by some studies 12,13 whereas others have cautioned against conservative management due to increasing maternal complications rates. 14 Natural history suggests that approximately 75% of women deliver within 1 month of PPROM and that the remaining 25% remain pregnant more than 1 month.…”

“…9 Neonates are at risk of mortality and morbidities due to pulmonary hypoplasia, extreme difficulty at resuscitation, sepsis, air leaks and chronic lung disease (CLD). 2,6,8,[10][11][12] In a systematic review and metaanalyses of reports from 1980 to 1999, significant lack of good quality information of outcomes of neonates born after early PPROM was identified. 6 Perinatal survival was reported to be <20% when PPROM occurred at both <20 and between 20 and 23 weeks gestation.…”

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“…In the paper from the Netherlands, a survival rate of very preterm neonates, who were admitted to neonatal intensive care, was in the range of 70 to 76 % still indicating a serious prognosis. However, overall prognosis for survival of very preterm has been substantially improved compared with the data published one or 2 decades ago [2,7]. The major result from the German trial with enrollment of very low birth weight infants is given by the fact that an increased risk for BPD must be anticipated in very low birth weight infants after PPROM.…”

Outcome of Twin Pregnancies Complicated By Early Second Trimester Rupture of Membranes in One Sac

“…Cases in which spontaneous delivery does not occur and the parents want to continue the pregnancy are rare and present a dilemma. Previous publications suggest that second trimester ROM may be associated with severe perinatal and neonatal morbidity such as fetal demise, premature labor and complications related to prematurity, hypoplastic lungs, limb contractures, and significant maternal morbidity due to infection (Everest et al, 2008;Farooqi et al, 1998;Grisaru-Granovsky et al, 2003;Hibbard et al, 1993;Lindner et al, 2002;Pristauz et al, 2008;Shumway et al, 1999;Vergani et al, 1994;Verma et al, 2006;Yang et al, 2004). In Israel, termination of the entire pregnancy is the common practice in these circumstances.…”