Acute Respiratory Distress Syndrome in Pregnancy

Narendra, Dharani Kumari; Muigai, David; Guntupalli, Kalpalatha K.

doi:10.1002/9781119129400.ch25

Cited by 2 publications

(2 citation statements)

References 73 publications

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“…The threshold for mechanical ventilation in pregnancy is also reduced for the reasons mentioned previously. With increasing oxygen supplementation without response and PaO2 <70, evidence suggests early intubation decreases the morbidity and mortality rates of pregnant patients with acute hypoxemic respiratory failure [ 21 ].…”

Section: Teratogenicitymentioning

confidence: 99%

COVID-19 and Pregnancy: Risk, Symptoms, Diagnosis, and Treatment

Hapshy

Aziz

Kahar

et al. 2021

SN Compr. Clin. Med.

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Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel virus responsible for causing an infection known as COVID-19. Several pulmonary and systemic manifestations of the illness have been described since the discovery of this virus. However, there have been higher-risk populations in which this infection has not been well studied nor documented. One of these populations includes the pregnant cohort. The purpose of this article is to describe the clinical manifestations of COVID-19 infection in the pregnant population and review the implications and sequelae of the infection throughout pregnancy and outcomes of live births. Also, we summarize the understanding and safety of current treatments and vaccination in pregnancy. This comprehensive review article comprises several case reports, case series, cohort studies, retrospective studies, and randomized clinical trials. Findings regarding maternal morbidity included an increased risk of acquiring severe COVID-19 infection requiring a higher level of inpatient hospital care along with an increased risk of preterm labor and cesarean delivery. Neonatal COVID-19 vertical transmission was shown to have conflicting data as there was a presence of transmission in certain retrospective studies and absence in others. There was also no evidence of teratogenicity from maternal COVID-19 infection. In conclusion, in part due to the unique physiologic state of pregnancy and part due to unknown factors, pregnant patients are at increased risk for negative outcomes of COVID-19 infection and must be classified as a high-risk population.

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Section: Teratogenicitymentioning

confidence: 99%

COVID-19 and Pregnancy: Risk, Symptoms, Diagnosis, and Treatment

Hapshy

Aziz

Kahar

et al. 2021

SN Compr. Clin. Med.

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“…The clinical setting in which pulmonary edema can occur in pregnancy are tocolytic therapy, preeclampsia, cardiac disease, sepsis, renal failure, very severe anemia, intracranial haemorrhage, amniotic fluid embolism or may be multifactorial. 2 The main mechanism of sepsis related pulmonary edema may be due to increased sensitivity of pregnant women to bacterial endotoxin, which increases pulmonary capillary permeability. Endothelial activation is the main denominator in pre-eclampsia and sepsis syndrome.…”

Section: Introductionmentioning

confidence: 99%

Prospective analytical study on acute pulmonary edema in obstetric intensive care unit

Nagaraj¹,

Meganathan²

2019

Int J Reprod Contracept Obstet Gynecol

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Background: Acute pulmonary oedema is an uncommon,but life threatening event in pregnancy. It causes significant morbidity and mortality due to pathophysiology of pre‐eclampsia and physiological changes of pregnancy which may aggravate certain pre-existing heart disease.Methods: This study was conducted to describe the clinical and epidemiological profile of antenatal women with acute pulmonary edema in obstetric ICU from January 2017 to December 2018 (2 years) in Mahathma Gandhi Memorial Government Hospital, Trichy, Tamil Nadu, India.Results: Acute pulmonary edema (n=31) accounts for 2.7% of ICU/HDU admissions in the study period. Most common etiology observed was severe preeclampsia (12 cases) followed by cardiogenic pulmonary edema (11 cases). Fluid overload, sepsis accounted for 7 cases and one mother with preexisting RHD had severe pre-eclampsia with acute pulmonary edema.Conclusions: Hypertensive disorders of pregnancy and heart disease contributes to major proportion of acute pulmonary edema in this study and it is imperative to recognize signs of critical illness. Skilled multidisciplinary teamwork plays an important role in optimizing maternal and fetal health.

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Acute Respiratory Distress Syndrome in Pregnancy

Cited by 2 publications

References 73 publications

COVID-19 and Pregnancy: Risk, Symptoms, Diagnosis, and Treatment

COVID-19 and Pregnancy: Risk, Symptoms, Diagnosis, and Treatment

Prospective analytical study on acute pulmonary edema in obstetric intensive care unit

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