Acute Renal Failure Due to Leptospirosis in a Renal Transplant Patient

Manfro, Roberto Ceratti; Boger, Marta V.; Kopstein, J; Gonçalves, Luís; Prompt, Carlos Alberto

doi:10.1159/000187338

Cited by 9 publications

(6 citation statements)

References 2 publications

(2 reference statements)

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“…Leptospirosis is a zoonotic disease caused by the spirochete Leptospira interrogans with a worldwide distribution, but more commonly identified in the tropics and subtropics. 3,126,127 There are 30 serogroups of Leptospira spp and approximately 240 serotypes. 3,127 Many mammals, particularly rodents, are reservoirs.…”

Section: Leptospirosis and Transplantationmentioning

confidence: 99%

Transplantation and tropical infectious diseases

Franco‐Paredes

Jacob

Hidrón

et al. 2010

International Journal of Infectious Diseases

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The number of transplant recipients with tropical infectious diseases is growing due to increasing international travel and the rising number of transplants taking place in the tropics and subtropics. With increases in population migration, the prevalence of individuals infected with geographically restricted organisms also rises. There are three potential categories of tropical infections in transplant patients: (1) donor-related infections transmitted by the graft or through transfusion of blood products; (2) reactivation or recrudescence of latent infections in the donor recipient; and (3) de novo acquisition of infection in the post-transplant period through the traditional route of infection. We present an overall discussion of the association of parasitic (protozoa and helminths) and non-parasitic (viral, bacterial, and fungal) tropical infectious diseases and solid-organ and hematopoietic transplantation. We also suggest potential screening guidelines for some of these tropical infections.

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Section: Leptospirosis and Transplantationmentioning

confidence: 99%

Transplantation and tropical infectious diseases

Franco‐Paredes

Jacob

Hidrón

et al. 2010

International Journal of Infectious Diseases

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“…Only 4 case reports of leptospirosis after solid organ transplantation have been published to date, all of which occurred in kidney transplant recipients (2)(3)(4)(5). This is the first report of leptospirosis in a liver transplant recipient, to our knowledge.…”

Section: Discussionmentioning

confidence: 82%

“…The published case reports are summarized in Table , including the present case. All cases presented with Weil's disease, and no patient presented with pulmonary hemorrhage.…”

Section: Discussionmentioning

confidence: 99%

A first report of leptospirosis after liver transplantation

Song

Abas

Andrade

et al. 2016

Transplant Infectious Dis

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Leptospirosis has been rarely reported in solid organ transplant recipients. We report the first case to our knowledge of leptospirosis in a liver transplant recipient who developed jaundice and renal insufficiency. We describe his favorable clinical progression and discuss the possible mechanisms involved in the more benign disease course. We also review the previously published cases of leptospirosis in solid organ transplant recipients. Although this disease does not appear to present any particularities in this context, we highlight the importance of clinical suspicion in this setting, particularly after liver transplantation.

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“…There are only 2 prior reported cases of leptospirosis in renal transplant recipients, 1 from Iran and 1 from Brazil (8, 9). Our report is the first case from North America to our knowledge.…”

Section: Discussionmentioning

confidence: 99%

Case of fulminant leptospirosis in a renal transplant patient

Gerasymchuk

Swami

Carpenter

et al. 2009

Transplant Infectious Dis

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We present a case of fulminant leptospirosis that was acquired in the suburban area by a 48-year-old male renal transplant recipient. He developed acute renal and hepatic failure with profound jaundice. Spirochetes were identified on liver biopsy. Weil's disease was suspected, and the diagnosis was further supported by a positive serum Leptospira interrogans icterohaemorrhagiae antibody titer. Unfortunately, he suffered from recurrent lower gastrointestinal bleeding, had a prolonged hospital course, and eventually succumbed to overwhelming sepsis. This case is the third report to our knowledge of leptospirosis in a renal transplant recipient in the English literature.

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Acute Renal Failure Due to Leptospirosis in a Renal Transplant Patient

Cited by 9 publications

References 2 publications

Transplantation and tropical infectious diseases

Transplantation and tropical infectious diseases

A first report of leptospirosis after liver transplantation

Case of fulminant leptospirosis in a renal transplant patient

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