Acute Renal Failure at the Lagos University Teaching Hospital: A 10-Year Review

Bamgboye, Ebun L.; Mabayoje, M O; Odutola, T. A.; Mabadeje, A. F. B.

doi:10.3109/08860229309065577

Cited by 37 publications

(18 citation statements)

References 3 publications

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“…Factors responsible for their poor clinical and metabolic state would include late presentation in advanced stage of AKI, predominantly community acquired nature of AKI, whose precipitating ailments were predominantly, sepsis, entero-invasive acute gastroenteritis, toxic nephropathies, as previously documented in AKI in developing countries [21, 22]. These causes of AKI are known to inflict severe renal injury necessitating RRT therapy [6, 7] and often associated with poor renal and patient outcomes.…”

Section: Discussionmentioning

confidence: 99%

Clinical Outcomes of Dialysis-Treated Acute Kidney Injury Patients at the University of Port Harcourt Teaching Hospital, Nigeria

2013

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Background. Acute kidney injury in adults is a common cause of hospitalization, associated with high morbidity and mortality especially in developing countries. In spite of RRT the in-hospital mortality rates remain high even in the developed countries. Though a proportion of our patients receive renal replacement therapy as part of their management, data on outcomes are sparse. Study Objective. To determine the clinical outcomes of dialysis-treated AKI in our hospital. Methods. A retrospective analysis of the clinical data of all adult AKI patients treated with haemodialysis at the University of Teaching Hospital during an interrupted six-year period was conducted. Analysis was done using SPSS version 17.0. Results. 34 males and 28 females with mean age of 41.3 ± 18.5 years were studied. The leading causes of AKI were sepsis (22.7%), acute glomerulonephritis (20.5%), acute gastroenteritis (15.9%), and toxic nephropathies (11.4%) and presented with mean e-GFR of 14.7 ± 5.8 mls/min/1.73 m2. Of the 62 patients, 29 (46.8%) were discharged from the hospital, 27 (43.5%) died in hospital, while 6 (9.7%) absconded from treatment. Survivors had better Rifle grade than those who died (P < 0.001). Conclusion. Hospital mortality rate of dialysis-treated AKI patients is high and the severity of renal damage at presentation may be an important factor.

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Section: Discussionmentioning

confidence: 99%

Clinical Outcomes of Dialysis-Treated Acute Kidney Injury Patients at the University of Port Harcourt Teaching Hospital, Nigeria

2013

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“…Susantitaphong et al reported the pooled incidence of AKI in adults to be 22% from met-analysis of studies that were mainly from Asia, America and Europe (2). The incidence of AKI also ranges between 30–70% among critically ill patients (4). It is the most common reason for in-hospital nephrology consultation in the United States (3).…”

Section: Introductionmentioning

confidence: 99%

“…It is the most common reason for in-hospital nephrology consultation in the United States (3). The burden of AKI is quite enormous due to associated morbidity, mortality, prolonged hospital stay and increase in overall health expenditure (4–6). …”

Section: Introductionmentioning

confidence: 99%

Assessment of knowledge of acute kidney injury among non-nephrology doctors in two government hospitals in Ondo City, Southwest, Nigeria

Adejumo

Akinbodewa

Alli

et al. 2017

Ethiop J Health Sci

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BACKGROUND: Adequate knowledge of acute kidney injury (AKI) among doctors is essential for its prevention, early diagnosis and management. Assessing knowledge of AKI among doctors is necessary to identify areas of deficiencies and key areas to be emphasized when organizing educational programs aimed at improving AKI care. This study determined the knowledge of AKI among non-nephrology doctors in Ondo City, Southwest Nigeria. MATERIALS AND METHODS: This was a cross-sectional descriptive study carried out in two government hospitals in Ondo City using a self-administered pretested questionnaire that assessed knowledge of AKI among non-nephrology doctors. P-value of < 0.05 was taken as significant. RESULTS: Eighty-one doctors participated in the study with a median post-graduation experience of 5.5 years. Sixty-one (78.2%) were in surgical specialty while the remaining worked in medical specialty. Only 1(1.2%) of the respondents had good knowledge of AKI, 56(69.2%) had fair knowledge while the remaining 24 (29.6%) had poor knowledge of AKI. Identified areas of deficiencies in knowledge of AKI were in mode of presentation, risk factors, potentially nephrotoxic medications, criteria for AKI definition and staging, newer AKI biomarkers and indications for renal replacement therapy. There was no significant association between knowledge of AKI and specialty (p=0.593) or year of practice (p=0.312) CONCLUSION: There were significant deficiencies in the knowledge of AKI amongst most non-nephrology doctors in Ondo city. We therefore recommend regular in-service training on AKI for practicing doctors.

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“…Acute postinfectious glomerulonephritis is frequently the cause of severe acute renal failure (requiring dialysis and/or admission to pediatric intensive care units) in underdeveloped countries. The proportion of cases of acute renal failure that correspond to acute postinfectious glomerulonephritis of demonstrated or assumed poststreptococcal etiology is 13% in New Delhi, 44 30% in Istanbul, 45 51.6% in Casablanca, 46 4.6% in Lagos, 47 27% in Bombay, 48 19.2% in Lucknow, 49 33% in Asunció n, 50 17.4% in Chandrigarth, 51 5.2% in Lima, 52 9.3% in Varanasi, 53 and 25% in Osun State, Nigeria. 54 …”

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confidence: 99%