1989
DOI: 10.1093/ndt/4.10.914
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Acute Renal Failure and Tubular Dysfunction Associated with Minimal Change Nephrotic Syndrome

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Cited by 8 publications
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“…Most reported cases refer to aged patients with minimal change disease, but a similar clinical presentation has been reported in other etiologies of nephrotic syndrome, such as membranous nephropathy [14][15][16]. Several hypotheses have been suggested to explain the pathogenesis of this acute renal failure associated with nephrotic syndrome: taking into account that most patients were old, some authors have speculated on an ischemic tubular necrosis, secondary to the hypovolemia that usually accompanies the nephrotic syndrome; aged patients could be more susceptible to this complication [17].…”
Section: Discussionmentioning
confidence: 95%
“…Most reported cases refer to aged patients with minimal change disease, but a similar clinical presentation has been reported in other etiologies of nephrotic syndrome, such as membranous nephropathy [14][15][16]. Several hypotheses have been suggested to explain the pathogenesis of this acute renal failure associated with nephrotic syndrome: taking into account that most patients were old, some authors have speculated on an ischemic tubular necrosis, secondary to the hypovolemia that usually accompanies the nephrotic syndrome; aged patients could be more susceptible to this complication [17].…”
Section: Discussionmentioning
confidence: 95%
“…This is particularly relevant if the nephrotic syndrome is severe, since the risk of developing AKI due to hypoperfusion and acute tubular necrosis (ATN) is increased in this setting. 148,178 …”
Section: Rationalementioning
confidence: 99%