Acute regulation of hematocrit and blood acid–base balance during severe hypoxic challenges in late chicken embryos (Gallus gallus)

Tazawa, Hiroshi; Andrewartha, Sarah J.; Burggren, Warren W.

doi:10.1016/j.resp.2012.08.002

Cited by 25 publications

(14 citation statements)

References 48 publications

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“…After internal pipping, gases gradually begin to be exchanged via the pulmonary respiratory system (Decuypere & Bruggeman, 2006;Mortola, 2009), andO 2 deficit and CO 2 saturation inside the egg air chamber are the main factors that induce external pipping and hatching per se (Mortola, 2009). In addition to changes in the gas exchange surfaces, hematological adjustments also occur, increasing gas exchange capacity during incubation: red blood cell counts (RBC), hematocrit (Ht) values, hemoglobin (Hb) levels increase, while mean corpuscular volume decreases (Morita et al, 2009;Tazawa et al, 2011Tazawa et al, , 2012.…”

Section: Egg O 2 and Co 2 Exchangesmentioning

confidence: 99%

Poultry Egg Incubation: Integrating and Optimizing Production Efficiency

Boleli

Morita

Matos

et al. 2016

Rev. Bras. Cienc. Avic.

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Due to its central position in the production chain, in-ovo development is influenced by pre-incubation factors that affect the quality of embryonated eggs and incubation conditions themselves, and both may influence egg hatchability and chick quality, as well as bird survival, growth performance, and phenotype in the field. The evolution of the incubation process over the years is characterized by significant scientific and technological development. Presently, the main current focuses of research are the manipulation of thermal incubation conditions, eggshell temperature, and the integrated effects of factors that influence incubation. In this context, one of the questions that needs to be asked is how effective are the current physical conditions of incubation to promote greater hatchability and better quality chicks, and higher survival and better performance in the field under adverse conditions or not. What are the new and future prospects for incubation? The purpose of this paper was to review the role of the physical agents of incubation, such as temperature, relative humidity, O 2 and CO 2 concentration, and egg turning and position from an integrated perspective, considering egg incubation as the transitional link between egg and poultry production.

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Section: Egg O 2 and Co 2 Exchangesmentioning

confidence: 99%

Poultry Egg Incubation: Integrating and Optimizing Production Efficiency

Boleli

Morita

Matos

et al. 2016

Rev. Bras. Cienc. Avic.

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“…The recovery of cyclic motility to the control level by the 20th minute of hypoxia may be accounted for by activation of regulatory mechanisms that were already sufficiently mature on D12-14. These may be, e.g., heart rate restoration against the background of hypoxia [17], changes in hematological respiratory variables [32,33], and redistribution of blood flow towards the most important organs (including brain) in response to hypoxia, which is known to become more pronounced with embryonic age [34]. These regulatory mechanisms may contribute to the restoration of motility under hypoxia.…”

Section: Effects Of Acute Hypoxia On the Cyclic Motility Of D10-15 Emmentioning

confidence: 99%

Age-related Changes in the Response of Embryonic Motility to Acute Hypoxia During the Third Quarter of Chick Embryogenesis

Nechaeva¹,

Алексеева²

2017

TOOENIJ

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Environmental factors may affect the growth, size, phenotype, behavior, and other characteristics of avian embryos at different developmental stages; however, the roles of individual embryonic physiological systems in these effects remain largely unclear. Embryonic motility is an important component of the prenatal development observed almost throughout embryogenesis and may be a precursor of post-hatching motor behavior. The influences of the environment on the development of motor behavior during embryogenesis (notably the embryonic motility affected by hypoxia) remain poorly studied. Consequently, using the chick embryo, we investigated the effect of acute hypoxia (10% or 5% О 2 for 20 or 40 min) on embryonic cyclic motility at incubation days (D) 10, 12, 14, and 15 using in vivo video recording. Hypoxia inhibited motility; specifically, the average duration of activity and inactivity phases during hypoxic exposure were shortened and prolonged, respectively. Age-related changes in the responses to 10% and 5% O 2 differed. The time course of the motility response to acute hypoxia varied during the D10-15 period and demonstrates that the embryo was capable of recovering motility under hypoxia. The recovery was likely enhanced with age due to maturation of regulatory capacity.

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“…Hypercapnia has been widely used as a stressor to probe the onset of acid-base balance; discussion of this extensive literature is beyond the scope of this review, and the reader is referred to the following studies for an entry into the literature Everaert et al, 2008a;Everaert et al, 2011;Tazawa et al, 2012;Burggren et al, 2012;Mueller et al, 2013b;Andrewartha et al, 2014;Mueller et al, 2014b;Burggren et al, 2015b;Mueller et al, 2015a). Like hypoxia, hypercapnia has differential levels in mortality/hatchability at different points in development (Taylor and Kreutziger, 1966;Taylor and Kreutziger, 1969;Everaert et al, 2007).…”

Section: Hypoxia Hypercapnia and Avian Critical Windowsmentioning

confidence: 99%

Cardio-respiratory development in bird embryos: new insights from a venerable animal model

2016

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-The avian embryo is a time-honored animal model for understanding vertebrate development. A key area of extensive study using bird embryos centers on developmental phenotypic plasticity of the cardio-respiratory system and how its normal development can be affected by abiotic factors such as temperature and oxygen availability. Through the investigation of the plasticity of development, we gain a better understanding of both the regulation of the developmental process and the embryo's capacity for self-repair. Additionally, experiments with abiotic and biotic stressors during development have helped delineate not just critical windows for avian cardio-respiratory development, but the general characteristics (e.g., timing and dose-dependence) of critical windows in all developing vertebrates. Avian embryos are useful in exploring fetal programming, in which early developmental experiences have implications (usually negative) later in life. The ability to experimentally manipulate the avian embryo without the interference of maternal behavior or physiology makes it particularly useful in future studies of fetal programming. The bird embryo is also a key participant in studies of transgenerational epigenetics, whether by egg provisioning or effects on the germline that are transmitted to the F1 generation (or beyond). Finally, the avian embryo is heavily exploited in toxicology, in which both toxicological testing of potential consumer products as well as the consequences of exposure to anthropogenic pollutants are routinely carried out in the avian embryo. The avian embryo thus proves useful on numerous experimental fronts as an animal model that is concurrently both of adequate complexity and sufficient simplicity for probing vertebrate cardio-respiratory development.

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Acute regulation of hematocrit and blood acid–base balance during severe hypoxic challenges in late chicken embryos (Gallus gallus)

Cited by 25 publications

References 48 publications

Poultry Egg Incubation: Integrating and Optimizing Production Efficiency

Poultry Egg Incubation: Integrating and Optimizing Production Efficiency

Age-related Changes in the Response of Embryonic Motility to Acute Hypoxia During the Third Quarter of Chick Embryogenesis

Cardio-respiratory development in bird embryos: new insights from a venerable animal model

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