Acute Q fever in hospitalised patients in Central Tunisia: report of 21 cases

Bellazreg, F.; Kaabia, N.; Hachfi, W.; Khalifa, M.; Jazia, E. Ben; Ghanouchi, N.; Brahem, A.; Bahri, F.; Létaief, A.

doi:10.1111/j.1469-0691.2008.02138.x

Cited by 10 publications

(6 citation statements)

References 5 publications

(6 reference statements)

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“…Comparing the clinical symptoms obtained in the present study with the so-called studies, the most non-specific symptoms for acute Q fever include fever, headache, chills, myalgia, arthralgia, weakness and fatigue and there are little differences in clinical symptoms. Although, some clinical signs such as hepatitis have a highlighted role in some countries[37,38], they were not observed in the current our study and some other studies. If this disease is a part of the health surveillance system in Iran and also if more clinical cases of Q fever are diagnosed and recorded, a much better view of clinical symptoms of Q fever can be obtained patients data.…”

Section: Discussioncontrasting

confidence: 85%

“…In Taiwan, fever (99%), relative bradycardia (73%), chills (69%) and headaches (45%) were the most common clinical symptoms [33]. In Tunisia, the highest clinical signs and symptoms in patients with acute Q fever were fever (100%), fatigue (76%), hepatitis (71.5%), chills (47.5%), headache (42.8%) and sweating (33.3%) [38]. Comparing the clinical symptoms obtained in the present study with the so-called studies, the most non-specific symptoms for acute Q fever include fever, headache, chills, myalgia, arthralgia, weakness and fatigue and there are little differences in clinical symptoms.…”

Section: Discussionmentioning

confidence: 99%

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Acute Q fever in febrile patients in northwestern of Iran

et al. 2017

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BackgroundQ fever is an endemic disease in different parts of Iran. This study aimed to investigate the prevalence of acute Q fever disease among at-risk individuals in northwestern Iran.MethodologyAn etiological study was carried out in 2013 in Tabriz County. A total of 116 individuals who were in contact with livestock and had a nonspecific febrile illness were enrolled in the study. IgG phase II antibodies against Coxiella burnetii were detected using ELISA.Principal findingsThe prevalence of acute Q fever was 13.8% (95% confidence interval [CI]: 8.0, 21.0%). Headache (87.5%) and fatigue and weakness (81.3%) were the dominant clinical characteristics among patients whit acute Q fever. Acute lower respiratory tract infection and chills were poorly associated with acute Q fever. Furthermore, 32% (95% CI: 24, 41%) of participants had a history of previous exposure to Q fever agent (past infection). Consumption of unpasteurized dairy products was a weak risk factor for previous exposure to C. burnetii.ConclusionThis study identified patients with acute Q fever in northwestern of Iran. The evidence from this study and previous studies conducted in different regions of Iran support this fact that Q fever is one of the important endemic zoonotic diseases in Iran and needs due attention by clinical physicians and health care system.

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Section: Discussioncontrasting

confidence: 85%

Section: Discussionmentioning

confidence: 99%

Acute Q fever in febrile patients in northwestern of Iran

et al. 2017

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“…On the other hand, hepatitis was considered as the major clinical presentation of acute Q fever cases admitted to E-Da hospital in Kaohsiung County in Southern Taiwan between 2004 and 2007 [34]. As elsewhere, Q fever in China should be suspected in febrile patients with hepatitis or atypical pneumonia who have a history of contact with domestic animals [35].…”

Section: Q Fever In Peoplementioning

confidence: 99%

Q fever in China: a systematic review, 1989–2013

El-Mahallawy

Kelly

et al. 2014

Epidemiol. Infect.

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Q fever, first described in 1937, is a worldwide zoonosis caused by Coxiella burnetii that has long been considered an under-reported and under-diagnosed illness. In China, the disease was initially reported in 1950 and in the last 25 years (1989-2013) there have been 29 reports on Q fever in China, nearly half of which were in the last 5 years. These publications have largely been in Chinese and in this review we summarize their findings to enable a better understanding of Q fever in China. The overall prevalence of C. burnetii infections in the reports is 10% (1139/11 209) in people, 15% (288/1918) in cattle and 12% (176/1440) in goats. These infections occurred widely in China with positive people and/or animals reported in 64 cities/municipalities from 19 provinces, particularly those in the eastern, western and northern areas. Cattle and goats had the highest seroprevalences of all the domestic animals studied and a wide variety of ticks were found to be infected. Mice were also commonly infected and had high copy numbers of C. burnetii DNA, suggesting they might be important in the epidemiology of Q fever in China.

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“…However, human Q fever cases are rarely described. While C. burnetii has been retrospectively identified as the cause for 9% of hospital admissions [36], only 21 cases of acute Q fever were reported in Tunisia between 2003 and 2007 [37]. Nevertheless, Q fever infections show no pathognomonic symptoms and are therefore often misdiagnosed.…”

Section: Majority Of Camels Seropositive For Anti-c Burnetii Iggmentioning

confidence: 99%

Viral and Bacterial Zoonotic Agents in Dromedary Camels from Southern Tunisia: A Seroprevalence Study

et al. 2022

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The rapid spread of SARS-CoV-2 clearly demonstrated the potential of zoonotic diseases to cause severe harm to public health. Having limited access to medical care combined with severe underreporting and a lack of active surveillance, Africa carries a high burden of neglected zoonotic diseases. Therefore, the epidemiological monitoring of pathogen circulation is essential. Recently, we found extensive Middle East respiratory syndrome coronavirus (MERS-CoV) prevalence in free-roaming dromedary camels from southern Tunisia. In this study, we aimed to investigate the seroprevalence, and thus the risk posed to public health, of two additional viral and two bacterial pathogens in Tunisian dromedaries: Rift Valley fever virus (RVFV), foot-and-mouth disease virus (FMDV), Coxiella burnetii and Brucella spp. via ELISA. With 73.6% seropositivity, most animals had previously been exposed to the causative agent of Q fever, C. burnetii. Additionally, 7.4% and 1.0% of the dromedaries had antibodies against Brucella and RVFV, respectively, while no evidence was found for the occurrence of FMDV. Our studies revealed considerable immunological evidence of various pathogens within Tunisian dromedary camels. Since these animals have intense contact with humans, they pose a high risk of transmitting serious zoonotic diseases during active infection. The identification of appropriate countermeasures is therefore highly desirable.

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Acute Q fever in hospitalised patients in Central Tunisia: report of 21 cases

Cited by 10 publications

References 5 publications

Acute Q fever in febrile patients in northwestern of Iran

Acute Q fever in febrile patients in northwestern of Iran

Q fever in China: a systematic review, 1989–2013

Viral and Bacterial Zoonotic Agents in Dromedary Camels from Southern Tunisia: A Seroprevalence Study

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