Acute Pyelonephritis

Scionti, Alessandra; Rossi, Piercarlo; Gulino, Pietro; Semeraro, Alessandro; Defilippi, Claudio; Tonerini, Michele

doi:10.1007/978-3-319-41866-7_17

Cited by 2 publications

(1 citation statement)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A variety of symptoms are associated with bladder infection, including pelvic pain, an increased urge to urinate, difficulty in urinating, and even blood in the urine. 4 T h e s p e c t r u m o f p r e d o m i n a n t pathogens UTIs is quite diverse and includes well-known causative agents, such as Proteus mirabilis, Enterococcus faecalis, Staphylococcus saprophy ticus, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae, various Candida species, and ubiquitous E. coli. 5 Repeated occurrences of UTIs have the potential to inflict lasting harm on the kidneys, culminating in irreversible damage, renal hypertension, and ultimately, renal failure, particularly in severe cases.…”

Section: Introductionmentioning

confidence: 99%

Antibacterial Activities of Secondary Metabolites Derived from Streptomyces sp. VITGV38 (MCC4869) against Selected Uropathogens

Hussain,

Christopher

2023

J. Pure Appl. Microbiol.

View full text Add to dashboard Cite

Streptomyces sp. VITGV38 (MCC8469) was obtained from the VIT University Microbiology Laboratory where it was isolated from tomato plants. This strain was mass-cultured for 15 days and its extracellular metabolites were extracted in ethyl acetate using a liquid–liquid extraction method. The antibacterial test was performed on the ethyl acetate crude extract against selected urinary tract pathogens, Proteus mirabilis (MTCC-442), Enterococcus faecalis (MTCC-439), Klebsiella pneumoniae (MTCC-109), and Escherichia coli (MTCC-1687), The extract developed a clear inhibition zone that measured between 17–21 mm. The minimum inhibition concentration was observed from a concentration of 25 μg/ml against all selected uropathogens. GC-MS analysis revealed 35 diverse compounds in the ethyl acetate crude extract, which includes 1,2 benzenedicarboxylic acid bis(2methylpropyl) ester, dibutyl phthalate, bis (2-ethylhexyl) phthalate, didodecyl phthalate, octadecanoic acid dodecyl ester, and dodecane. These six compounds are the major antimicrobial compounds present in the ethyl acetate extract. VITGV38 showed greyish aerial mycelium. Scanning electron microscopy revealed elliptical spores with a chain-like smooth orientation.

show abstract

Section: Introductionmentioning

confidence: 99%