Acute post‐streptococcal glomerulonephritis in Central Australia

Dowler, James; Wilson, Angela

doi:10.1111/ajr.12568

Cited by 12 publications

(12 citation statements)

References 17 publications

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“…Similarly, a 2010-2014 study from Central Australia found that all children hospitalised with APSGN were Aboriginal and Torres Strait Islander. 24 The disparities in kidney disease burden for Aboriginal and Torres Strait Islander children in Australia is akin to other First Nations' experience around the world. For example, a study from New Zealand reported that the incidence of APSGN was 7-to 17-fold higher amongst Pacific Islander and M aori children compared to those of European descent.…”

Section: Discussionmentioning

confidence: 99%

Clinical characteristics of hospitalised children with acute post‐streptococcal glomerulonephritis in the Top End of Australia

Chong

Hung

Hohls

et al. 2023

J Paediatrics Child Health

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Aims Despite the declining incidence of acute post‐streptococcal glomerulonephritis (APSGN) in Australia, there is still a significant burden of disease amongst Aboriginal and Torres Strait Islander people in the Northern Territory. Childhood APSGN has been highlighted as a predictor of chronic kidney disease in this population. We aimed to describe clinical characteristics and outcomes of hospitalised children with APSGN in the Northern Territory. Methods Single‐centre, retrospective cohort study of children (<18 years) with APSGN admitted to a tertiary hospital in the Top End of the Northern Territory between January 2012 and December 2017. Cases were confirmed using the Centre for Disease Control case definition guidelines. Data were extracted from the case notes and electronic medical records. Results There were 96 cases of APSGN with median age of 7.1 years (interquartile range (IQR) 6.7–11.4). Majority were Aboriginal and Torres Strait Islander (90.6%) and from rural and remote areas (82.3%). Preceding skin infections were identified in 65.5% and sore throat in 27.1%. Severe complications included hypertensive emergencies (37.4%), acute kidney injury (43.8%) and nephrotic‐range proteinuria (57.7%). All children improved from their acute illness with supportive medical therapy; however, only 55 out of 96 (57.3%) children were followed up within 12 months of their acute illness. Conclusions APSGN disproportionately affects Aboriginal and Torres Strait Islander children and highlights the need for continued and improved public health response. There is room for significant improvement in the medium‐ and long‐term follow‐up of affected children.

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Section: Discussionmentioning

confidence: 99%

Clinical characteristics of hospitalised children with acute post‐streptococcal glomerulonephritis in the Top End of Australia

Chong

Hung

Hohls

et al. 2023

J Paediatrics Child Health

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“…infection. Delayed access to specialized burn centers located in major Australian cities, due to distance and transport availability, may contribute to 69,72 This health inequity may be minimized in these cases through careful education, ongoing monitoring, and early treatment of Aboriginal and Torres Strait Islander burn injury survivors and their family, to help prevent further manifestation of Streptococcus sp. or significant comorbidities later in life.…”

Section: Discussionmentioning

confidence: 99%

Burn Injuries in Hospitalized Australian Children—An Epidemiological Profile

Ryder

Mackean

Hunter

et al. 2020

Journal of Burn Care &Amp; Research

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Globally, First Nations children sustain burns at a higher rate than other children. Little is understood about how health inequities contribute, especially from an Indigenous viewpoint. We analysed data from the Burns Registry of Australian and New Zealand (BRANZ) for acute burns in children (<16 years) admitted to hospital between October 2009 and July 2018. Descriptive statistics examined equity variables in patient and injury characteristics. Poisson regression was used to describe factors associated with bacterial infection. Indigenous research methods were used throughout. Aboriginal and Torres Strait Islander children represented 10.4% of the study population. Health inequities were present for Aboriginal and Torres Strait Islander children with longer hospital length of stay (9.5 vs 4.6 days), rural residency (61.3% vs 13.9%), lower socioeconomic status (72.2% vs 34.9%), and more flame burns (19.5% vs 10.6%) compared to other Australian children. Streptococcus sp. infection risk was 4 times greater in Aboriginal and Torres Strait Islander children compared to other Australian children. Flame burns and high percentage total body surface area burns were a risk for Staphylococcus sp. and Streptococcus sp. infection in all children. The epidemiological profile for burn injuries managed in Australian burns centres differs between Aboriginal and Torres Strait Islander children and other children, indicating persistent health inequities. These differences should be considered in the development of injury prevention strategies and the clinical management of burn injuries for Aboriginal and Torres Strait Islander children and their families.

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“…Aboriginal children in Australia have the highest incidence of post-infectious glomerulonephritis (PIGN) in the world; recent studies from Central Australia reported an incidence of 229/100,000 person years [8]. Furthermore, rates in parts of Australia continue to be elevated despite reduction in PIGN rates in many other parts of the world [9].…”

Section: Australia-aboriginal and Torres Strait Islandersmentioning

confidence: 99%

Kidney Health of Indigenous Children: Insights from Australia, Aotearoa New Zealand, and Canada

2022

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Purpose of Review This review seeks to highlight the common and unique factors that impact the kidney health of Indigenous children in Australia, Aotearoa New Zealand, and Canada with a particular interest on efforts to improve their kidney health outcomes and the framework to pursue future efforts. Recent Findings In the period since the adoption of the United Nations (UN) Declaration on the Rights of Indigenous People (UNDRIP) there has been a number of studies documenting poorer renal health outcomes and potential causes amongst Indigenous paediatric populations in Australia, Aotearoa New Zealand, and Canada. There is a shortage of studies that look at interventions to improve these outcomes. Summary Poorer kidney health outcomes amongst Indigenous children are rarely genetic and appear to be more related to societal inequities. Reported efforts to improve outcomes are few but have demonstrated the ability to make change and with sustained focus on reducing inequities there is hope to improve the renal health of Indigenous children.

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Acute post‐streptococcal glomerulonephritis in Central Australia

Cited by 12 publications

References 17 publications

Clinical characteristics of hospitalised children with acute post‐streptococcal glomerulonephritis in the Top End of Australia

Clinical characteristics of hospitalised children with acute post‐streptococcal glomerulonephritis in the Top End of Australia

Burn Injuries in Hospitalized Australian Children—An Epidemiological Profile

Kidney Health of Indigenous Children: Insights from Australia, Aotearoa New Zealand, and Canada

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