Acute polyethylene microplastic (PE-MPs) exposure activates the intestinal mucosal immune network pathway in adult zebrafish (Danio rerio)

Yuan, Yin; Sepúlveda, Marisol; Bi, Baoliang; Kong, Lingfu; Yan, Hui; Gao, Yu

doi:10.1016/j.chemosphere.2022.137048

Cited by 18 publications

(4 citation statements)

References 80 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…PE is one of the most critical plastic polymers with the highest consumption and most commonly found in air [40,35,41]. AMPs with PE polymer type can come from using plastic materials as plastic bags, storage containers, packaging, and toys [42].…”

Section: Amps Polymer Typementioning

confidence: 99%

Airborne microplastics in Bandung and Osaka: Concentration and characteristics

Hidayat,

Kitano,

Tani

et al. 2024

E3S Web of Conf.

View full text Add to dashboard Cite

Plastic is a material that is widely used in everyday life. It can be degraded into small-sized fragments (< 5 mm) called microplastics (MPs). Research on MPs has primarily focused on the aquatic environment, while studies on airborne MPs (AMPs) are still in their early stages. In this study, AMPs at two locations (Bandung (Indonesia) and Osaka (Japan)) were characterized by attenuated total imaging and micro-Fourier transform infrared spectroscopy, as a preliminary study. The concentrations of AMPs in total suspended particulates (TSP) in Bandung and Osaka ranged from 1.03 to 14.27 particles/m3 and from 0.63 to 3.29 particles/m3, respectively. AMPs in both locations were fragmented, with dominant Feret diameters ranging from 1 to 20 μm.

show abstract

Section: Amps Polymer Typementioning

confidence: 99%

Airborne microplastics in Bandung and Osaka: Concentration and characteristics

Hidayat,

Kitano,

Tani

et al. 2024

E3S Web of Conf.

View full text Add to dashboard Cite

show abstract

“…Lu et al reveals that PS exposure causes the local infection and lipid accumulation in the liver of fish and disrupts the energy metabolism. 87 In addition, Deng et 89 Li et al demonstrates that the secretion of IL-1α is increased in the serum of rats exposed to PE but decreased in the Th17 and Treg cells among CD4 + cells. 90 Lim et al observes that inhalation of PS causes the upregulated expression of the inflammatory protein (TGF-β and TNF-α) in lung tissue of rats.…”

Section: Metabolic Disordermentioning

confidence: 99%

“…Microplastics can induce immune response in the body. Yuan et al reports that PE exposure activates the intestinal immune network pathway of zebrafish and produces mucosal immunoglobulin . Li et al demonstrates that the secretion of IL-1α is increased in the serum of rats exposed to PE but decreased in the Th17 and Treg cells among CD4 + cells .…”

Section: Toxic Effects Of Microplasticsmentioning

confidence: 99%

Potential Health Impact of Microplastics: A Review of Environmental Distribution, Human Exposure, and Toxic Effects

Tao

Wang

et al. 2023

Environ. Health

View full text Add to dashboard Cite

Microplastics are ubiquitous in the global environment. As a typical emerging pollutant, its potential health hazards have been widely concerning. In this brief paper, we introduce the source, identification, toxicity, and health hazard of microplastics in the human. The literature review shows that microplastics are frequently detected in environmental and human samples. Humans are potentially exposed to microplastics through oral intake, inhalation, and skin contact. We summarize the toxic effects of microplastics in experimental models like cells, organoids, and animals. These effects consist of oxidative stress, DNA damage, organ dysfunction, metabolic disorder, immune response, neurotoxicity, as well as reproductive and developmental toxicity. In addition, the epidemiological evidence suggests that a variety of chronic diseases may be related to microplastics exposure. Finally, we put forward the gaps in toxicity research of microplastics and their future development directions. This review will be helpful to the understanding of the exposure risk and potential health hazards of microplastics.

show abstract

“…The relative abundance of the Plesiomonas genus was favorably linked with the expression of immune-related genes ( pigr , il10 , and ighv4-5 ). 251 Microplastic exposure can impair immune function by suppressing the apoptosis-related molecular pathways and calcium signaling of the complement system, among other immune-system-disrupting effects. 252 These findings imply that microplastics affect the complement system and the capacity of the body to fight off foreign substances.…”

Section: Interaction With the Circulatory Systemmentioning

confidence: 99%