Acute Phase Proteins response and their clinical application in veterinary medicine

Abstract

Acute phase proteins (APP) are the group of blood proteins that the synthesis happens in a quick and intense manner in response to external or internal challenges, such as infection, inflammation, surgical trauma or stress. These proteins have been used as biomarkers of inflammation, infection and trauma in human medicine, but have been relatively under-utilised in the context of veterinary medicine due to the unknown diagnostic possibilities.
 The purpose of this paper is to update the knowledge about APPs in veterinary medicine, reviewing results from different studies suggesting possible clinical applicability of APP measurement as a valuable tool for veterinary diagnostic and prognostic.

Anti-Vasculogenic, Antioxidant, and Anti-Inflammatory Activities of Sulfated Polysaccharide Derived from Codium tomentosum: Pharmacokinetic Assay

“…APPs are blood proteins produced during the acute-phase response, can interact with both pathogen elements and cells to modulate the inflammatory response, and are susceptible to identifying a wide range of disorders that affect an animal’s health and recognize inflammation or infections. As di Filippo et al [ 69 ] reported, APPs are immediately and accurately used to show the presence of inflammatory and infectious diseases. In the present study, albumin alpha, beta, and gamma globulins were identified by routine electrophoresis.…”