Acute pesticide poisoning outcomes: a nationwide study in Taiwan

Chen, Chieh-Fan; Lin, Hsing-Lin; Chou, Huei-Yin; Hsu, Wei-Chih; Shi, Hon-Yi

doi:10.1136/emermed-2013-203238

Cited by 4 publications

(4 citation statements)

References 26 publications

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“…Fifth, because we identified intoxication events based on ICD9 codes and the antidotes administered, there may have been some misclassification. However, previous studies based on similar databases showed reliable results [2,12,[47][48][49][50][51]. Our current research thus provides an overview of intoxication events in Taiwan between 2006 and 2013.…”

Section: Strengths and Limitationssupporting

confidence: 51%

Incidence of intoxication events and patient outcomes in Taiwan: A nationwide population-based observational study

Chen

Chan

2020

PLoS ONE

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Background Intoxicated patients were frequently managed in the emergency departments (ED) with few studies at national level. The study aimed to reveal the incidence, outcomes of intoxications and trend in Taiwan. Methods Adults admitted to an ED due to an intoxication event between 2006 and 2013 were identified using the Taiwan National Health Insurance Research Database. The rate of intoxication and severe intoxication events, mortality rate, hospital length of stay (LOS), and daily medical costs of these patients were analyzed. Changes over time were analyzed using Joinpoint models. Multivariable generalized regressions with GEE were used to assess the effect of sex, age, and presence of prior psychiatric illness. Results A total of 20,371 ED admissions due to intoxication events were identified during the study period, and the incidence decreased with annual percentage change of 4.7% from 2006 to 2013. The mortality rate, hospital LOS, and daily medical costs were not decreased over time. Males and geriatric patients had more severe intoxication events, greater mortality rates, and greater daily medical costs. Patients with psychiatric illnesses had higher mortality rates and a longer hospital LOS, but lower daily medical expenses. Conclusion From 2006 to 2013, there was a decline in the incidence of ED admission for intoxication events in Taiwan. Males, geriatric patients, and those with psychiatric illnesses had greater risks for severe intoxication and mortality.

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Section: Strengths and Limitationssupporting

confidence: 51%

Incidence of intoxication events and patient outcomes in Taiwan: A nationwide population-based observational study

Chen

Chan

2020

PLoS ONE

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“…11,12 However, in a South African and a Taiwanese study, there were more female cases of acute poisoning with pesticides where most were related to organophosphate poisoning. 13,14 This study found that 51.7% of organophosphate poisonings were intentional, whereas 21.7% were accidental and 26.6% had unknown circumstances. Similarly, a study from India showed 64.6% of cases of intentional poisoning, 34.4% of accidental poisoning, and 1% of unknown circumstances.…”

Section: Discussionmentioning

confidence: 87%

“…11,12 However, in a South African and a Taiwanese study, there were more female cases of acute poisoning with pesticides where most were related to organophosphate poisoning. 13,14…”

Section: Discussionmentioning

confidence: 99%

Epidemiology of Organophosphate Poisoning in the Tshwane District of South Africa

Razwiedani

Rautenbach

2017

Environ�Health�Insights

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Background:Organophosphate poisoning is a major public health problem in South Africa. Individuals get exposed to organophosphate in both the domestic and industrial spheres.Method:A cross-sectional study was conducted using retrospective, secondary data of organophosphate poisoning cases over a 3-year period, reported at the Tshwane District surveillance office. Data were analysed using Microsoft Excel, and Epi Info version 7 was used for descriptive statistics.Results:A total of 207 cases were reported with ages ranging from 10 months to 59 years. Most of the cases were men (58.9%). Intentional poisoning accounted for 51% of cases. Unintentional poisoning accounted for 21.7% of cases, and 26.5% of cases had unknown circumstances of poisoning. A significant number (50.2%) of intentional poisonings were suicide related. Nonsuicidal cases accounted for 47.4% of cases, and deliberate unlawful poisoning accounted for 2.4% of cases. The mortality rate for the whole group was 3.4%.Conclusions:Improvement in data collection on organophosphate poisoning is essential to properly measure the burden of the problem. More effective regulatory controls for pesticide use are needed in South Africa.

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“…Third, because we identi ed intoxication events based on ICD9 codes and the antidotes administered, there may have been some misclassi cation. However, previous studies based on similar databases showed reliable results (22,(37)(38)(39)(40)(41)(42). Our current research thus provides an overview of intoxication events in Taiwan between 2006 and 2013.…”

Section: Strengths and Limitationsmentioning

confidence: 88%

Incidence of Intoxication Events and Patient Outcomes in Taiwan: a Nationwide Population-based Observational Study

Chen

Chan

Su³

2020

Preprint

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Background Intoxicated patients were frequently managed in the emergency departments (ED) with few studies at national level. The study aimed to reveal the incidence, outcomes of intoxications and trend in Taiwan.Methods Adults admitted to an ED due to an intoxication event between 2006 and 2013 were identified using the Taiwan National Health Insurance Research Database. The rate of intoxication and severe intoxication events, mortality rate, hospital length of stay (LOS), and daily medical costs of these patients were analyzed. Changes over time were analyzed using Joinpoint models. Subgroup analyses were used to assess the effect of sex, age, and presence of a prior psychiatric illness.Results A total of 20,371 ED admissions due to intoxication events were identified during the study period, and the incidence decreased with annual percentage change of 4.7% from 2006 to 2013. The mortality rate, hospital LOS, and daily medical costs were not decreased over time. Males and geriatric patients had more severe intoxication events, greater mortality rates, and greater daily medical costs. Patients with psychiatric illnesses had higher mortality rates and a longer hospital LOS, but lower daily medical expenses.Conclusion From 2006 to 2013, there was a decline in the incidence of ED admission for intoxication events in Taiwan. Males, geriatric patients, and those with psychiatric illnesses had greater risks for severe intoxication and mortality.

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Acute pesticide poisoning outcomes: a nationwide study in Taiwan

Abstract: In APP patients, treatment by a high-volume physician can reduce LOS and treatment cost.

Cited by 4 publications

References 26 publications

Incidence of intoxication events and patient outcomes in Taiwan: A nationwide population-based observational study

Incidence of intoxication events and patient outcomes in Taiwan: A nationwide population-based observational study

Epidemiology of Organophosphate Poisoning in the Tshwane District of South Africa

Incidence of Intoxication Events and Patient Outcomes in Taiwan: a Nationwide Population-based Observational Study

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