Acute partial sleep deprivation and high-intensity interval exercise effects on postprandial endothelial function

Papadakis, Zacharias; Forsse, Jeffrey S.; Peterson, Matt A.

doi:10.1007/s00421-020-04468-5

Cited by 14 publications

(19 citation statements)

References 103 publications

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“…Aerobic exercise of moderate to high intensity has the potential to counter the excessive formation of oxidative and nitrative stress associated with elevated ADMA concentrations [55]. In previous studies, ADMA concentrations were reported to be 29% lower after completing 10 to 15 min of moderate-intensity aerobic exercise and 14% lower after a max exercise test [25,54,55]. Alterations in ADMA for our study appear to be time sensitive, with the most significant decreases being present at 24-HR.…”

Section: Discussionsupporting

confidence: 52%

“…Therefore, our cohort did not exhibit characteristics of endothelial dysfunction at baseline. Additionally, HIIE did not elicit as great of response in FMD when compared to healthy populations [25,51,52], indicating some level of endothelial impairment.…”

Section: Discussionmentioning

confidence: 77%

“…Pre-and post-inflation peak shear rates were estimated from blood flow using the following equation [20,25,45]: Shear rate = velocity × 8/initial resting vessel diameter 2.6. Blood Sampling Blood samples were drawn after an 8 to 12 h fast, while participants practiced stable dietary intake, medication use, and refrained from any moderate or strenuous physical activity other than the exercise completed for this study.…”

Section: Analysis Of Fmd Datamentioning

confidence: 99%

“…High-intensity interval exercise (HIIE) stimulates greater amounts of oxidative stress when compared to moderate-intensity exercise [14]. However, HIIE may also produce a higher post-exercise antioxidant response when compared to moderate-intensity exercise [23][24][25]. HIIE can potentially ameliorate oxidative and nitrative stress in the vascular endothelium in CKD, thus creating a net antioxidant environment in the hours post-exercise.…”

Section: Introductionmentioning

confidence: 99%

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The Influence of an Acute Bout of Aerobic Exercise on Vascular Endothelial Function in Moderate Stages of Chronic Kidney Disease

Forsse

Papadakis

Peterson

et al. 2022

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Chronic kidney disease (CKD) is directly influenced by the deleterious effects of systemic inflammation and oxidative stress. The vascular endothelium may transiently respond to aerobic exercise and improve post-exercise vascular renal function in moderate stages of CKD. Brachial artery flow-mediated dilation (FMD) is a nitric-oxide-dependent measure of endothelial function that is transiently potentiated by exercise. The purpose of the study was to determine the acute influence of a single bout of high-intensity interval exercise (HIIE) or steady-state moderate-intensity exercise (SSE) on endothelial dysfunction in moderate stages of CKD. Twenty participants (n = 6 men; n = 14 women) completed 30 min of SSE (65%) and HIIE (90:20%) of VO2reserve in a randomized crossover design. FMD measurements and blood samples were obtained before, 1 h, and 24 h post-exercise. FMD responses were augmented 1 h post-exercise in both conditions (p < 0.005). Relative to pre-exercise measures, total antioxidant capacity increased by 4.3% 24 h post-exercise (p = 0.012), while paraoxonase-1 was maintained 1 h and elevated by 6.1% 24 h after SSE, but not HIIE (p = 0.035). In summary, FMD can be augmented by a single episode of either HIIE or SSE in moderate stages of CKD. Modest improvements were observed in antioxidant analytes, and markers of oxidative stress were blunted in response to either SSE or HIIE.

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Section: Discussionsupporting

confidence: 52%

Section: Discussionmentioning

confidence: 77%

Section: Analysis Of Fmd Datamentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The Influence of an Acute Bout of Aerobic Exercise on Vascular Endothelial Function in Moderate Stages of Chronic Kidney Disease

Forsse

Papadakis

Peterson

et al. 2022

Life

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“…Sleep disorders related to inflammation and sympathetic activation lead to a change in blood vessel architecture, characterized by elastic fiber fracture and disorder, an increase in inflammatory cells, lipid peroxidation, inflammation, and sympathetic activation, which may induce endothelial dysfunction. Endothelial dysfunction is a critical factor in the increased risk of CVD [ 91 - 95 ]. In models of acute and chronic SD in healthy volunteers, Sauvet et al [ 96 , 97 ], Dettoni et al [ 98 ], measured biomarkers of microvascular reactivity and endothelial activation, elevated plasma E-selectin levels, and significantly increased sympathetic neural activity during SD.…”

Section: Mechanisms Of Chd Caused By Sdmentioning

confidence: 99%

Effects of sleep deprivation on coronary heart disease

Wei

Duan

Guo

2022

Korean J Physiol Pharmacol

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The presence of artificial light enables humans to be active 24 h a day. Many people across the globe live in a social culture that encourages staying up late to meet the demands of various activities, such as work and school. Sleep deprivation (SD) is a severe health problem in modern society. Meanwhile, as with cardiometabolic disease, there was an obvious tendency that coronary heart disease (CHD) to become a global epidemic chronic disease. Specifically, SD can significantly increase the morbidity and mortality of CHD. However, the underlying mechanisms responsible for the effects of SD on CHD are multilayered and complex. Inflammatory response, lipid metabolism, oxidative stress, and endothelial function all contribute to cardiovascular lesions. In this review, the effects of SD on CHD development are summarized, and SD-related pathogenesis of coronary artery lesions is discussed. In general, early assessment of SD played a vital role in preventing the harmful consequences of CHD.

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Effects of Acute Exercise on Cardiac Autonomic Response and Recovery in Non-Dialysis Chronic Kidney Disease Patients

Papadakis

Grandjean

Forsse

2022

Research Quarterly for Exercise and Sport

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Acute partial sleep deprivation and high-intensity interval exercise effects on postprandial endothelial function

Cited by 14 publications

References 103 publications

The Influence of an Acute Bout of Aerobic Exercise on Vascular Endothelial Function in Moderate Stages of Chronic Kidney Disease

The Influence of an Acute Bout of Aerobic Exercise on Vascular Endothelial Function in Moderate Stages of Chronic Kidney Disease

Effects of sleep deprivation on coronary heart disease

Effects of Acute Exercise on Cardiac Autonomic Response and Recovery in Non-Dialysis Chronic Kidney Disease Patients

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