Acute parasitic and other infectious myelopathies in the tropics: 26 cases at the University Hospital in Conakry

Cisse, Fodé Abass; Ekué, W. A.; Barry, Louncény Fatoumata; Barry, Souleymane; Touré, Mohamed Lamine; Cissé, A

doi:10.1684/mst.2016.0632

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“…TB remains and stays a real public health problem in Sub-Saharan African countries in both pulmonary and extrapulmonary forms. 1 , 11…”

Section: Discussionmentioning

confidence: 99%

“…In most cases, they would result in the spread of a vertebral focus 1 , 3 - 5 or in exceptional cases, 2 , 10 they remain associated with multidrug-resistant pulmonary meningitis, especially in tropical environments. 3 , 11…”

Section: Discussionmentioning

confidence: 99%

“…The interest of this work resides in the fact that these observations illustrate the primitive medullary lesions of TB origin without osteo-vertebral lesions and the diagnostic difficulties that they comprise in the vast group of acute and chronic myelopathies in Sub-Saharan Africa. 11…”

Section: Introductionmentioning

confidence: 99%

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Medullar Kock without Pott: 13 cases observed at the university hospital center of Conakry, Guinea

Cisse¹,

Sakadi²,

Tassiou³

et al. 2019

CJN

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Background: The diagnostic certainty of medullar tuberculosis (TB) without Pott disease is difficult to establish in a tropical environment with the large group of infectious, parasitic, and systemic myelopathies, despite the increasing availability of magnetic resonance imaging (MRI) data and improvement of biological exploration platforms. Methods: We retrospectively analyzed the files of 186 patients hospitalized in the Department of Neurology and Neurosurgery of the University Hospital Center of Conakry, Guinea, between 2008 and 2016 for the management of non-compressive and compressive myelopathy. Biological evidence of TB infection was demonstrated for 13 (6.9%) patients. Results: Infectious clinical picture prior to the development of neurological signs was reported in 11 patients (84.6%). The neurological signs were summed up by the existence of a sensitivo-motor semiology of progressive evolution (100% of cases) with sphincter disorders in 11 patients (84.6%) and a medullary compression symptomatology with a lesion and under lesion syndrome from the outset in 4 patients (30.8%). Medullary MRI revealed an extensive intramedullary hypersignal in 9 patients with non-compressive myelopathy and in 4 cases, the lesions appeared in T1 hypersignal and T2 isosignal were localized. Lumbar puncture (LP) revealed lymphocytic pleocytosis, hypoglucorrhage (0.3 to 0.5 g/l), and leukocytosis. Conclusion: This study reveals a classic clinical, biological, neuroradiological, and evolutionary profile of compressive and non-compressive myelopathies. These results are important for the therapeutic and evolutionary discussion of TB myelopathies for good management.

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“…TB remains and stays a real public health problem in Sub-Saharan African countries in both pulmonary and extrapulmonary forms. 1 , 11…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Medullar Kock without Pott: 13 cases observed at the university hospital center of Conakry, Guinea

Cisse¹,

Sakadi²,

Tassiou³

et al. 2019

CJN

View full text Add to dashboard Cite

show abstract

Acute parasitic and other infectious myelopathies in the tropics: 26 cases at the University Hospital in Conakry

Cited by 1 publication

References 0 publications

Medullar Kock without Pott: 13 cases observed at the university hospital center of Conakry, Guinea

Medullar Kock without Pott: 13 cases observed at the university hospital center of Conakry, Guinea

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