Acute Pancreatitis in a Pregnant Patient With Coronavirus Disease 2019 (COVID-19)

Narang, Kavita; Szymanski, Linda M.; Kane, Sunanda V.; Rose, Carl H.

doi:10.1097/aog.0000000000004287

Cited by 16 publications

(43 citation statements)

References 13 publications

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“…Narang et al [ 46 ] reported the case of a 20-year-old pregnant woman hospitalized for sudden respiratory decompensation in the setting of confirmed COVID-19 infection with obesity (BMI = 36.1 kg/m 2 ) and following cholecystectomy 2 years prior. CT showed COVID-19 pneumonia.…”

Section: Case Reports and Cohort Studies On Ap In Covid-19 In The Literature Searchmentioning

confidence: 99%

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Association between acute pancreatitis and COVID-19 infection: What do we know?

Jabłońska

Mrowiec

2021

WJGS

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The disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also called coronavirus disease 2019 (COVID-19), first originated in Wuhan, China, displaying atypical pneumonia-like respiratory symptoms in affected patients. SARS-CoV-2 primarily attacks the respiratory system, and the most common symptoms include cough, shortness of breath, and fever. However, its impact on the digestive system has been shown, and various clinical gastrointestinal manifestations of this disease have been recognized. Some reports have shown acute pancreatitis (AP) as the initial symptom in patients with COVID-19. AP may be a consequence of direct pancreatic damage by the virus because pancreatic acinar cells contain angiotensin-converting enzyme 2 receptor proteins, and SARS-CoV-2 can bind to these receptors, causing pancreatic injury. Moreover, AP may be a secondary indicator of cytokine storms and altered inflammatory responses. Our review of the literature shows that SARS-CoV-2 appears to be a new etiological infectious factor related to AP. In this manuscript, a comprehensive review of case reports and case series of patients with AP and COVID-19 is presented. All reports on COVID-19-associated AP are summarized. All cases are thoroughly analyzed and discussed in-depth.

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Section: Case Reports and Cohort Studies On Ap In Covid-19 In The Literature Searchmentioning

confidence: 99%

“…After delivery, her clinical condition improved. She was discharged in stable condition on postpartum day 3[ 46 ].…”

Section: Case Reports and Cohort Studies On Ap In Covid-19 In The Literature Searchmentioning

confidence: 99%

Association between acute pancreatitis and COVID-19 infection: What do we know?

Jabłońska

Mrowiec

2021

WJGS

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“…In our analysis, six pregnant women went into spontaneous premature labor 12,14,[16][17][18][19]22 , two had premature rupture of membranes 18,19 and one had a placenta abruption 20 . Three evolved to spontaneous vaginal delivery 13,17,18 and, among them, only one received intrapartum oxytocin 18 .…”

Section: Resultsmentioning

confidence: 99%

“…Three newborns presented with respiratory distress after birth 18,21,23 , and only one of them tested positive for Covid-19 by RT-PCR from a nasopharyngeal swab 18 . SARS-CoV-2 serology studies of one baby showed immunoglobulin G positive.…”

Section: Resultsmentioning

confidence: 99%

Premature birth and COVID-19: an integrative review/ Nascimento prematuro e COVID-19: uma revisão integrativa

Pontual¹,

Silva²,

Oliveira³

et al. 2021

Braz. J. Hea. Rev.

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OBJECTIVE: To review the current scientific evidence of premature birth related to coronavirus disease 2019 (Covid-19).METHODS: An integrative review was carried out by three independent researchers, based on the literature available in the MEDLINE (via PubMed) and LILACS databases, using the descriptors "coronavirus infections" and "premature birth". This research included case reports or case series published until 26th February 2021, in English or Portuguese. After reading the articles in their entirety, those specifically related to premature birth in pregnant women positive for Covid-19 were selected. Initially, a total of 21 articles were found, 19 were analyzed in full-text and 13 were finally selected for this study. RESULTS: The rate of prematurity was not reflected at the expense of spontaneous premature birth, since these were relatively low, with a cesarean section percentage higher than 80%. Most reports describe the termination of pregnancy by cesarean section due to maternal-fetal hemodynamic instability. It is known that Covid-19 can cause serious maternal or perinatal outcomes; however, it is suggested that the indication of the delivery route be individualized and the importance of quality prenatal care is emphasized.CONCLUSION: Covid-19 prematurity seems to be elevated by the increased number of preterm births due to cesarean sections possibly to improve maternal and neonatal clinical status. However, more studies are needed to prove the hypothesis of spontaneous premature labor caused directly by SARS-CoV-2.

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“…In fact, in several observational case-control studies on pancreatic injury, there was an increase in serum amylase/lipase as a marker of pancreatic damage in 8.5-17.3% of cases. Interestingly, pancreatic abnormalities have been more frequently noted in the sub-group of patients having severe COVID disease [17][18][19]22 .…”

Section: Discussionmentioning

confidence: 99%

Manifestations of Acute Pancreatitis in Severe COVID-19 Patients: Is This a Coincidence?

Romadhon

Suryantoro²,

Windradi³

et al. 2021

IJTID

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Coronavirus Disease-19 (COVID-19) adalah penyakit yang disebabkan oleh Severe Acute Acute Respiratory Coronavirus-2 (SARS-CoV2) yang berasal dari China, menyebar dengan cepat ke seluruh bagian negara lain yang menyebabkan pandemi dunia. Dengan derajat gejala yang bervariasi yang disebabkan oleh COVID-19, virus ini menyebabkan kerusakan pada beberapa organ, baik karena efek inﬂ amasi tidak langsung maupun efek sitopatik. Data terkait keterlibatan pankreas dalam kasus COVID-19 masih belum jelas. Seorang laki-laki usia 83 tahun dirawat karena gejala COVID-19 berat. Dalam perawatan, pasien memberikan gejala dan tanda pankreatitis akut tanpa diketahui faktor resiko yang terkait. Pada pemeriksaan didapatkan RT-PCR SARS-CoV2 positif dari swab nasofaring, amilase lipase yang meningkat serta gambaran ultrasound khas untuk pankreatitis akut. Tatalaksana pasien tetap berdasar pada kasus SARS-CoV2 dengan isolasi, oksigenasi, pemberian anti virus dan suportif. Pemberian antibiotik juga didasarkan pada terapi empiris yang kemudian disesuaikan hasil sensitiﬁ tas kultur. Skor prognosis pankreatitis menunjukkan risiko kematian pada kasus moderate. Pada perjalanan, pasien meninggal karena shock sepsis. Prevalensi pankreatitis akut dan tingkat keparahannya perlu diamati. Dalam artikel ini, kami menyajikan kasus pankreatitis akut yang terjadi pada COVID-19 parah dengan faktor risiko yang tidak diketahui.Diagnosis penyebab kasus pankreatitis masih belum jelas tetapi beberapa bukti autopsi kasus infeksi SARS-CoV2 dengan pankreatitis menyebutkan bahwa infeksi virus ini dapat menyebabkan injuri pada pankreas.. Kondisi sepsis dapat diakibatkan infeksi virus SARS-CoV2 (viral sepsis) atau ko-infeksi bakteri. Oleh karena itu, rasionalisasi penggunaan antibiotik juga diperlukan. Kasus ini merupakan kasus yang membutuhkan managemen holisitik dan intensif karena kedua kondisi berpotensi dapat memperberat satu sama lain. Pengenalan awal kegawatan serta terapi tepat merupakan hal yang penting dapat menunjang kesintasan pasien.

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Acute Pancreatitis in a Pregnant Patient With Coronavirus Disease 2019 (COVID-19)

Abstract: Acute pancreatitis can be a complication of primary coronavirus disease 2019 (COVID-19) in pregnant women

Cited by 16 publications

References 13 publications

Association between acute pancreatitis and COVID-19 infection: What do we know?

Association between acute pancreatitis and COVID-19 infection: What do we know?

Premature birth and COVID-19: an integrative review/ Nascimento prematuro e COVID-19: uma revisão integrativa

Manifestations of Acute Pancreatitis in Severe COVID-19 Patients: Is This a Coincidence?

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