Acute pancreatitis in a COVID‐19 patient: An unusual presentation

Acherjya, Goutam Kumar; Rahman, Masudur; Islam, Md. Ariful; Alam, Abm Saiful; Tarafder, Keya; Rahman, Mohammad Mostafizur; Ali, Mohammad Daud; Deb, Shudip Ranjan

doi:10.1002/ccr3.3412

Cited by 12 publications

(18 citation statements)

References 12 publications

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“…Acherjya et al [ 35 ] reported the case of a 57-year-old female physician with breast and larynx cancers, with fever, generalized body pain, fatigue, arthralgia, and loss of smell for 2 d. She was treated for COVID-19 pneumonia (favipiravir, prophylactic dose of enoxaparin, and oxygen inhalation). On day 5 after symptom onset, her oxygen saturation decreased to 87%.…”

Section: Case Reports and Cohort Studies On Ap In Covid-19 In The Literature Searchmentioning

confidence: 99%

“…Therefore, AP was recognized and conservatively treated (zero diet, intravenous fluids, intravenous broad-spectrum antibiotics, omeprazole, and pethidine hydrochloride). She was discharged in good general condition following 14 d without any pancreatitis-related complications[ 35 ].…”

Section: Case Reports and Cohort Studies On Ap In Covid-19 In The Literature Searchmentioning

confidence: 99%

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Association between acute pancreatitis and COVID-19 infection: What do we know?

Jabłońska

Mrowiec

2021

WJGS

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The disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also called coronavirus disease 2019 (COVID-19), first originated in Wuhan, China, displaying atypical pneumonia-like respiratory symptoms in affected patients. SARS-CoV-2 primarily attacks the respiratory system, and the most common symptoms include cough, shortness of breath, and fever. However, its impact on the digestive system has been shown, and various clinical gastrointestinal manifestations of this disease have been recognized. Some reports have shown acute pancreatitis (AP) as the initial symptom in patients with COVID-19. AP may be a consequence of direct pancreatic damage by the virus because pancreatic acinar cells contain angiotensin-converting enzyme 2 receptor proteins, and SARS-CoV-2 can bind to these receptors, causing pancreatic injury. Moreover, AP may be a secondary indicator of cytokine storms and altered inflammatory responses. Our review of the literature shows that SARS-CoV-2 appears to be a new etiological infectious factor related to AP. In this manuscript, a comprehensive review of case reports and case series of patients with AP and COVID-19 is presented. All reports on COVID-19-associated AP are summarized. All cases are thoroughly analyzed and discussed in-depth.

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Section: Case Reports and Cohort Studies On Ap In Covid-19 In The Literature Searchmentioning

confidence: 99%

Section: Case Reports and Cohort Studies On Ap In Covid-19 In The Literature Searchmentioning

confidence: 99%

Association between acute pancreatitis and COVID-19 infection: What do we know?

Jabłońska

Mrowiec

2021

WJGS

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“…Table 1 describes the clinical characteristics of the reported cases of COVID-19-associated acute pancreatitis, including ours. As noted, the symptoms of acute pancreatitis may appear 2-14 days after the pulmonary symptoms [2], [7], [8], [10], [12], [16], [17], [18], [19] or concurrently with the pulmonary symptoms [3], [4], [9], [11], [13], [14], [15] and rarely as the sole presentation of COVID-19 [5]. Interestingly, acute pancreatitis was diagnosed without abdominal signs in one case report [20].…”

Section: Discussionmentioning

confidence: 95%

“…Although rare, the most common causes of viral-associated pancreatitis are mumps, coxsackie, hepatitis B, cytomegalovirus, varicella-zoster virus, and herpes simplex virus [6]. However, since the declaration of COVID-19 as a pandemic by WHO on March 11, 2020, a growing number of cases of COVID-19-associated acute pancreatitis have been reported [2], [3], [4], [5], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20]. In one study, the prevalence of COVID-19 associated pancreatitis was found to be 0.39% [21].…”

Section: Discussionmentioning

confidence: 99%

“…The first aspect is related to acute pancreatitis, which is primarily supportive as described by the reviewed cases as well as ours. The second aspect of the treatment of this clinical entity is related to COVID-19, which remains unclear because some drugs used in treating COVID-19 such as favipiravir [10] and ritonavir [27] may cause pancreatic damage. In our series, ritonavir-containing drugs were continued after the onset of acute pancreatitis, while in the cases reviewed, the actions toward these drugs varied from case to case.…”

Section: Discussionmentioning

confidence: 99%

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Coronavirus Disease-19-associated Acute Pancreatitis: Report of Three Cases and Review of Case Reports

Khan

Sulaiman

Nair

et al. 2021

Open Access Maced J Med Sci

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BACKGROUND: Reports on coronavirus disease 2019 (COVID-19) associated with acute pancreatitis continue to emerge. In this series, we present three cases of acute pancreatitis associated with COVID-19 with no obvious etiology. CASE REPORTS: The first case was a 47-year-old man who presented with severe abdominal periumbilical pain, preceded by fever and dry cough. Based on a positive COVID-19 polymerase chain reaction (PCR) test and elevated serum amylase and lipase >3 times the upper normal limit, the diagnosis of COVID-19 and acute pancreatitis were established. The next case was a 57-year-old man with confirmed COVID-19 who developed severe epigastric pain radiating to the back and was associated with nausea and vomiting. His serum amylase and lipase were elevated >3 times the upper normal limit confirming the diagnosis of acute pancreatitis. The third case was a 31-year-old man who presented to the emergency department with a few hours of severe epigastric pain radiating to the back associated with nausea and vomiting. Two days before his presentation, he had a runny nose and fever. A combination of serum amylase and lipase elevation, >3 times the upper normal limits, and a positive COVID-19 PCR test were obtained concurrently, confirming the diagnosis of COVID-19 associated acute pancreatitis. All patients were admitted to the Mesaieed Hospital COVID-19 facility and received treatment for COVID-19 according to our local guidelines, while acute pancreatitis was treated conservatively. All three patients were discharged in good condition. CONCLUSION: This case series suggests a possible correlation between COVID-19 and acute pancreatitis.

Acute pancreatitis in a COVID‐19 patient: An unusual presentation

Abstract: This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Cited by 12 publications

References 12 publications

Association between acute pancreatitis and COVID-19 infection: What do we know?

Association between acute pancreatitis and COVID-19 infection: What do we know?

Coronavirus Disease-19-associated Acute Pancreatitis: Report of Three Cases and Review of Case Reports

Dengue presenting as a case of acute pancreatitis—A rare case report

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