Acute Pancreatitis During COVID-19 Pneumonia

Shinohara, Takayuki; Otani, Amato; Yamashita, Marie; Wakimoto, Yuji; Jubishi, Daisuke; Okamoto, Koh; Kanno, Yoshihiro; Ikeda, Mahoko; Ishigaki, Kazunaga; Nakai, Yosuke; Harada, Sohei; Okugawa, Shu; Koike, Kazuhiko; Moriya, Kyoji

doi:10.1097/mpa.0000000000001695

Cited by 12 publications

(9 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, a case report on a resected gallbladder after cholecystitis highlighted the presence of SARS‐CoV‐2 within the tissue, thus confirming viral presence 113 . Pancreatic involvement, defined as an increase in serum amylase and/or lipase or overt acute pancreatitis, has also been described in few reports or case series 115–118 . In the largest retrospective case series, elevated serum lipase was found in 14/83 cases (16.8%), and this was correlated with higher rates of admission to the intensive care unit and need for intubation 117 .…”

Section: Clinical Featuresmentioning

confidence: 91%

“…113 Pancreatic involvement, defined as an increase in serum amylase and/or lipase or overt acute pancreatitis, has also been described in few reports or case series. [115][116][117][118] In the largest retrospective case series, elevated serum lipase was found in 14/83 cases (16.8%), and this was correlated with higher rates of admission to the intensive care unit and need for intubation. 117 However, the number of cases described is rather small and most patients were severely obese.…”

Section: Biliary and Pancreatic Manifestationsmentioning

confidence: 96%

See 1 more Smart Citation

Implications of SARS‐CoV‐2 infection for neurogastroenterology

Marasco

Lenti

Cremon

et al. 2021

Neurogastroenterology Motil

View full text Add to dashboard Cite

Health Organization reported more than 32 million cases and 995 thousands deaths from 235 countries related to this pandemic. 2 The clinical course of SARS-CoV-2 infection can span a wide range from asymptomatic to a rapidly progressing and life-threatening disease, most commonly associated with a variety of symptoms, such as fever, cough, dyspnea, pneumonia, acute respiratory distress syndrome, systemic inflammatory response syndrome, and multiple

show abstract

Section: Clinical Featuresmentioning

confidence: 91%

Section: Biliary and Pancreatic Manifestationsmentioning

confidence: 96%

Implications of SARS‐CoV‐2 infection for neurogastroenterology

Marasco

Lenti

Cremon

et al. 2021

Neurogastroenterology Motil

View full text Add to dashboard Cite

show abstract

“…Shinohara et al [ 36 ] described the case of a 58-year-old Japanese man with fever and increasing dyspnea for 7 d. He was hospitalized due to COVID-19 pneumonia. The first CT did not show abnormalities in the pancreas.…”

Section: Case Reports and Cohort Studies On Ap In Covid-19 In The Literature Searchmentioning

confidence: 99%

“…He was discharged in stable condition on day 30 of hospitalization. According to the authors, it is possible that their patient developed AP from other etiologies, considering drug-induced pancreatitis caused by favipiravir and nafamostat mesilate[ 36 ].…”

Section: Case Reports and Cohort Studies On Ap In Covid-19 In The Literature Searchmentioning

confidence: 99%

Association between acute pancreatitis and COVID-19 infection: What do we know?

Jabłońska

Mrowiec

2021

WJGS

View full text Add to dashboard Cite

The disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also called coronavirus disease 2019 (COVID-19), first originated in Wuhan, China, displaying atypical pneumonia-like respiratory symptoms in affected patients. SARS-CoV-2 primarily attacks the respiratory system, and the most common symptoms include cough, shortness of breath, and fever. However, its impact on the digestive system has been shown, and various clinical gastrointestinal manifestations of this disease have been recognized. Some reports have shown acute pancreatitis (AP) as the initial symptom in patients with COVID-19. AP may be a consequence of direct pancreatic damage by the virus because pancreatic acinar cells contain angiotensin-converting enzyme 2 receptor proteins, and SARS-CoV-2 can bind to these receptors, causing pancreatic injury. Moreover, AP may be a secondary indicator of cytokine storms and altered inflammatory responses. Our review of the literature shows that SARS-CoV-2 appears to be a new etiological infectious factor related to AP. In this manuscript, a comprehensive review of case reports and case series of patients with AP and COVID-19 is presented. All reports on COVID-19-associated AP are summarized. All cases are thoroughly analyzed and discussed in-depth.

show abstract

“…Si bien las causas más comunes de pancreatitis aguda son: cálculos de la vía biliar, antecedente de consumo de alcohol, enfermedades metabólicas (hipertrigliceridemia, hipercalcemia) o autoinmunes, hipotensión; el historial clínico del paciente no mostró ninguno de estos antecedentes, ni los estudios de extensión realizados; algunos autores mencionan que también el tratamiento con glucocorticoides puede ser origen de elevación de las enzimas pancreáticas, sin embargo esto no está del todo probado. En el contexto del paciente, determinamos que, en sí, la principal etiología sospechosa es el propio COVID 19 vs origen medicamentoso (paciente recibió tratamiento con dexametasona previo a hospitalización) (Shinohara et al, 2020) (Hadi et al, 2020. Aproximadamente el 10% de las pancreatitis agudas son causadas por infecciones, en su mayoría virales www.anatomiadigital.org (coxsackievirus, citomegalovirus, herpes, hepatitis, VIH, Influenza AH1N1, Epstein Barr), las pancreatitis medicamentosas son mucho más infrecuentes con una incidencia del 5% (Brikman et al, 2020) (Kandasamy, 2020) (Aloysius et al, 2020).…”

Section: Discussionunclassified

Pancreatitis Aguda en COVID 19 caso clínico y revisión de la literatura.

Cedeño

Flores²,

Pérez³

et al. 2021

View full text Add to dashboard Cite

Introducción: En 2019 se identificó un nuevo coronavirus como la causa del brote de una enfermedad que se originó en China. Este virus se conoce como el coronavirus tipo 2 del síndrome respiratorio agudo grave (SARS-CoV-2). En marzo de 2020, la Organización Mundial de la Salud (OMS) declaró el brote de la COVID-19 como pandemia. Aunque la gravedad de la infección es determinada sobre todo por la aparición de neumonía grave e insuficiencia respiratoria aguda, se han descrito además afectaciones en distintos aparatos y sistemas. A nivel del aparato digestivo son frecuentes la aparición de diarrea, vómitos y dolor abdominal. La pancreatitis aguda es un proceso inflamatorio reversible, el cual resulta de la activación de enzimas digestivas liberadas por esta glándula. Esta entidad patológica está asociada con múltiples etiologías, por lo que algunos estudios han reportado una posible lesión pancreática asociada a la infección por SARS-CoV-2 debido a un efecto citopático directo del virus o posterior a la respuesta inflamatoria sistémica. Objetivo: Determinar las manifestaciones pancreáticas del COVID 19, lo que es fundamental para ayudar al diagnóstico y orientar hacia el pronóstico de esta patología. Metodología: En el presente artículo comentamos un caso de pancreatitis aguda que podría estar relacionado con la infección por COVID 19, además se realiza una búsqueda sistemática de bibliografía actual y relevante relacionada con el tema. Resultados: Las manifestaciones pancreáticas del SARS-CoV2 no son tan comunes, sin embargo la presencia simultánea de ambas entidades se ha asociado a una mayor mortalidad hospitalaria. Conclusión: Se dispone de escasa evidencia de rigor científico a nivel real para determinar al COVID 19 como factor directo causal de Pancreatitis Aguda, se requiere de mayores estudios multicéntricos y de mayor impacto.

show abstract

Acute Pancreatitis During COVID-19 Pneumonia

Cited by 12 publications

References 10 publications

Implications of SARS‐CoV‐2 infection for neurogastroenterology

Implications of SARS‐CoV‐2 infection for neurogastroenterology

Association between acute pancreatitis and COVID-19 infection: What do we know?

Pancreatitis Aguda en COVID 19 caso clínico y revisión de la literatura.

Contact Info

Product

Resources

About