Acute pancreatitis due to methanol toxicity during the COVID‐19 pandemic

Sadeghi, Mahdieh; Zakariaei, Zakaria; Fakhar, Mahdi; Tabaripour, Rabeeh; Banimostafavi, Elham Sadat; Azadeh, Hossien

doi:10.1002/ccr3.4943

Cited by 3 publications

(1 citation statement)

References 19 publications

(39 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[14][15][16] Similarly, other sporadic cases of methanol toxicity were described during the COVID-19 pandemic worldwide. [17][18][19] Methanol poisoning represents 92% of the incidents stated by the global event-based surveillance with at least one or more deaths. 20 In addition, methanol poisoning puts major burdens on the healthcare system because of its associated high mortality and morbidity rates despite the effective patients management.…”

Section: Introductionmentioning

confidence: 99%

Neutrophil-to-lymphocyte ratio versus platelet-to-lymphocyte ratio in predicting clinical outcomes in acute methanol poisoning

et al. 2022

View full text Add to dashboard Cite

Acute methanol poisoning is a global health concern. This study was designed to compare the prognostic roles of neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and their combination in the prediction of clinical outcomes in methanol-intoxicated patients as well as to evaluate their associations with all initial patients’ characteristics. We conducted a cross-sectional study among methanol-intoxicated patients. A total of 109 patients were enrolled in the study. Thirty-four (31%) patients died during hospital admission while 30 (27.5%) patients developed visual loss. Most of the unfavorable findings were evident in patients with high NLR and PLR. Neutrophil-to-lymphocyte ratio and PLR can excellently differentiate between survivors and non-survivors with an area under the curve (AUC) of 0.991 vs 0.923, respectively. Platelet-to-lymphocyte ratio showed an accepted discrimination ability to differentiate between patients who developed and patients who did not develop visual loss, AUC of 0.734, however, NLR showed no discrimination, AUC of 0.558. We concluded that NLR and PLR can serve as valuable tools in risk-stratifying patients and prognosticating outcomes in acute methanol poisoning. Platelet-to-lymphocyte ratio is superior to NLR as a predictive factor in patients with permanent visual impairment. However, a combination of NLR with PLR can develop a more powerful prediction for overall clinical outcomes.

show abstract