Acute pancreatitis and hyperparathyroidism: A case series

Chowdhury, Sudipta Dhar; Kurien, Reuben Thomas; Pal, Sandip; Jeyaraj, Veena; Joseph, Anjilivelil Joseph; Dutta, Amit Kumar; Chandramohan, Anuradha; Abraham, Deepak Thomas; Augustine, Joby; Hephzibah, Julie; Simon, Ebby George

doi:10.1007/s12664-013-0430-2

Cited by 13 publications

(9 citation statements)

References 9 publications

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“…This examination confirmed the hyperfunctional character of this parathyroid laterocervical nodule. Parathyroid lesion was in any case an adenoma in our series, as in Indian series [ 2 , 7 , 12 ]. It was ectopic in two cases out of 5.…”

Section: Discussionmentioning

confidence: 54%

Primary Hyperparathyroidism and Pancreatitis: A Rare Association with Multiple Facets

Diallo

Fall

Ndiaye

et al. 2016

International Scholarly Research Notices

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Primary hyperparathyroidism (PHPT) is rarely associated with the occurrence of acute or chronic pancreatitis. Hypercalcemia plays a major role in the pathogenesis. We report five cases of pancreatitis revealing PHPT. Patients and Methods. This is a retrospective study of 4 years, including all patients admitted to intensive care unit or gastroenterology department, for an acute or chronic pancreatitis revealing primary hyperparathyroidism. Results. We included 5 patients, all female, with mean age 54 years [40–76 years]. The PHPT was in all cases revealed by acute pancreatitis (AP). This one was oedematous in four cases and severe in one case. It occurred twice in calcified chronic pancreatitis (CCP). There was hypercalcemia in all cases. The PHPT was associated with a high rate of parathyroid hormone in 4 cases. The secreting lesion was an adenoma in 5 cases. Two patients had in addition bilateral renal calcifications. The outcome was favorable in 4 patients among whom 3 have had parathyroid surgery. A death was noted by superinfection of necrosis in the case of severe AP. Conclusion. The occurrence of pancreatitis during hyperparathyroidism is rare. Normal or elevated calcemia during acute or chronic pancreatitis should always get attention.

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Section: Discussionmentioning

confidence: 54%

Primary Hyperparathyroidism and Pancreatitis: A Rare Association with Multiple Facets

Diallo

Fall

Ndiaye

et al. 2016

International Scholarly Research Notices

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“…The frequency of pancreatitis associated with hyperparathyroidism in patients of 20-70 years of age has been reported to range from 1.5% to 15.3% ( 5 , 6 ). Hyperparathyroidism is often only discovered after two or three episodes of recurrent pancreatitis ( 7 , 8 ). Similarly, in this case, the patient had a history of pancreatitis; however, she had not been diagnosed with hyperparathyroidism prior to the present admission.…”

Section: Discussionmentioning

confidence: 99%

Acute Pancreatitis with Disturbed Consciousness Caused by Hyperparathyroidism

et al. 2018

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Although hyperparathyroidism has been reported to cause acute pancreatitis, little is known about the mechanism involved. This study describes the case of an 86-year-old woman with acute pancreatitis and consciousness disturbance caused by hyperparathyroidism and hypercalcemia, respectively. The consciousness disturbance caused by severe hypercalcemia probably masked the typical symptoms associated with pancreatitis because she did not report abdominal pain during the clinical course.

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“…There are numerous causes of acute pancreatitis (22-44) ( Table 1 ) including alcohol ingestion, biliary tract disease (gallstones/malignancy), surgery/postoperative states (45), trauma (36), metabolic disorders (hypertriglyceridemia, hypercalcemia)(46-49), infections (adenovirus, mumps, ascariasis, mycoplasma) (44, 50), and drugs (the most common include thiazides, sulfa, methyldopa, and procainamide) (51, 52). Malignancies of the pancreas and bile ducts may result in pancreatitis due to obstruction/stenosis of the exocrine pancreatic ducts (53-57).…”

Section: Discussionmentioning

confidence: 99%

Pancreatitis: A Forensic Perspective

Gill

2016

Academic Forensic Pathology

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Among the numerous etiologies of acute and chronic pancreatitis, several underlying causes (e.g., chronic alcohol abuse, trauma, medical therapy) may result in a death that is reportable to the medical examiner/coroner. As such, forensic pathologists are likely to encounter pancreatitis at autopsy and therefore must be familiar with its etiologies, mechanisms of death, autopsy findings, and medicolegal investigation. This review will focus on the aspects of pancreatitis that may be useful to forensic pathologists in their daily practice. This includes determining if acute or chronic pancreatitis caused or contributed to death as well as determining the etiologically specific proximate cause of death. Current theories of how these various processes result in inflammation of the pancreas are reviewed.

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Acute pancreatitis and hyperparathyroidism: A case series

Cited by 13 publications

References 9 publications

Primary Hyperparathyroidism and Pancreatitis: A Rare Association with Multiple Facets

Primary Hyperparathyroidism and Pancreatitis: A Rare Association with Multiple Facets

Acute Pancreatitis with Disturbed Consciousness Caused by Hyperparathyroidism

Pancreatitis: A Forensic Perspective

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