Acute osteomyelitis in children in Ibadan, Nigeria. Is surgical decompression necessary?

Ogunlade, SO; Omololu, AB; Alonge, T O

doi:10.4314/ajbr.v7i3.54154

Cited by 5 publications

(7 citation statements)

References 13 publications

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“…Osteomyelitis is known to be commoner in children, which explains why we have a lower median age. There are variable reports of gender predilection of osteomyelitis in SCD, while some reported lower incidence in males, some reported higher prevalence, and others reported equal distribution [31][32][33]. In this study, males were more likely to present with osteomyelitis than females (M:F = 1.8:1).…”

Section: Discussionmentioning

confidence: 48%

Variations and characteristics of the various clinical phenotypes in a cohort of Nigerian sickle cell patients

et al. 2021

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Background: Sickle cell anaemia affects about 4 million people across the globe, making it an inherited disorder of public health importance. Red cell lysis consequent upon haemoglobin crystallization and repeated sickling leads to anaemia and a baseline strain on haemopoiesis. Vaso-occlusion and haemolysis underlies majority of the chronic complications of sickle cell. We evaluated the clinical and laboratory features observed across the various clinical phenotypes in adult sickle cell disease patients. Methods: Steady state data collected prospectively in a cohort of adult sickle cell disease patients as out-patients between July 2010 and July 2020. The information included epidemiological, clinical and laboratory data. Results: About 270 patients were captured in this study (165 males and 105 females). Their ages ranged from 16 to 55 years, with a median age of 25 years. Sixty-eight had leg ulcers, 43 of the males had priapism (erectile dysfunction in 8), 42 had AVN, 31 had nephropathy, 23 had osteomyelitis, 15 had osteoarthritis, 12 had cholelithiasis, 10 had stroke or other neurological impairment, 5 had pulmonary hypertension, while 23 had other complications. Frequency of crisis ranged from 0 to >10/year median of 2. Of the 219 recorded, 148 of the patients had been transfused in the past, while 71 had not. Conclusion:The prevalence of SLU, AVN, priapism, nephropathy and the other complications of SCD show some variations from other studies. This variation in the clinical parameters across different clinical phenotypes indicates an interplay between age, genetic and environmental factors.

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Section: Discussionmentioning

confidence: 48%

Variations and characteristics of the various clinical phenotypes in a cohort of Nigerian sickle cell patients

et al. 2021

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“…The presenting clinical features observed in Table 2 were not different from the ones documented in previously published reports. [ 11 12 ]…”

Section: Discussionmentioning

confidence: 99%

“…In this series, the percentage of those who recovered fully and adjudged cured is within the range in other published reports. [ 11 12 ] The inability of seventeen patients (22.4%) to have operative surgical intervention after investigations and diagnosis due to financial constraint indicates that poverty is an important factor in the morbidity associated with pyogenic bone infection in our environment. The bulk of this category of patients had chronic pyogenic osteomyelitis that was sequel to acute hematogenous bone infection.…”

Section: Discussionmentioning

confidence: 99%

“…Most of the published reports on pyogenic bone infection in children focused on either of these clinical forms of presentations. [ 1 2 6 8 9 10 11 ] Overall, there is a paucity of published study that defines the pattern of childhood pyogenic osteomyelitis as one-disease state with a spectrum of pathological features. [ 12 13 ] The limited data have necessitated this study aimed at determining the pattern and outcome of childhood pyogenic osteomyelitis in a low-resource setting.…”

Section: Introductionmentioning

confidence: 99%

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Childhood Pyogenic Osteomyelitis in Abakaliki, South East Nigeria

Omoke¹

2018

Niger J Surg

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Background:Pyogenic osteomyelitis is an important child health problem in developing countries. It is a one-disease state with a spectrum of pathological features and clinical forms ranging from acute to chronic presentation. Its pattern of presentation varies from and within subregions. The aim of this study was to determine the pattern and outcome of childhood pyogenic osteomyelitis in a low-resource environment.Materials and Methods:This was a retrospective study of all the children aged 18 years and under seen with pyogenic osteomyelitis in Federal Teaching Hospital Abakaliki between January 2005 and December 2015.Results:In 76 patients, there was pyogenic osteomyelitis involving 85 bones. Female-to-male ratio was 1:1.7, and the mean age was 9.9 ± 5.1 years. The clinical forms of presentation were acute in 16 (21.1%), subacute in 10 (13.2%), and chronic in 50 (65.8%) patients. Acute osteomyelitis was the more likely form of presentation among infants (P < 0.001) and urban children (P < 0.011) whereas subacute and chronic osteomyelitis were more likely among the older children (P < 0.001) and rural residents (P < 0.011). Staphylococcus aureus was the most common isolated pathogen. Anemia, septic arthritis, and pathological fractures were the three top complications observed. Fifty patients (65.8%) recovered and adjudged cured, 9 (11.8%) were lost to follow-up, and 17 (22.4%) were unable to afford the financial cost of the treatment.Conclusion:In our environment, chronic pyogenic osteomyelitis sequel to acute hematogenous bone infection in childhood is common. Poverty is also a limiting factor in its definitive treatment. These calls for a policy response aimed at improved care and preventive strategies based on the observed pattern.

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“…Similar to our study, the increased of OA prevalence significantly increased among participants aged 60–69 years [ 20 , 21 ]. Another study stated that the overall prevalence of KOA in elderly people >60 years was 28.2% [ 22 ]. In the present study based on BMI, 85.96% of respondents are above the normal body mass index.…”

Section: Discussionmentioning

confidence: 99%

An evaluation of knee osteoarthritis pain in the general community—Asir region, Saudi Arabia

Kandasamy,

Almaghaslah,

Almanasef

et al. 2024

PLoS ONE

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Background Knee osteoarthritis (KOA) is one of the most common conditions resulting in disability, particularly in the elderly population. Osteoarthritis (OA) is the most common articular disease and the leading cause of chronic disability in the developed world. Objective This study was carried out to evaluate knee pain in the Asir region of Saudi Arabia. An analytical cross-sectional survey design was adopted in the Asir region from April 2023 to August 2023 to assess the knee pain of the adult population using an anonymous online questionnaire. Results Of 1234, 332 were men (26.90) and 902 were women (73.09). WOMAC index score category 55.34% (n = 683) of the subjects had a low risk (score <60), 28.68% (n = 354) had a moderate risk (score 60–80), and 15.96% (n = 197) had a high risk (score ≥81) for KOA. According to clinical criteria, 79.33% (n = 979) of the study subjects had OA. Age group, gender 2.17 (1. 67–2.82) [OR 2.17; 95% CI 1.67–2.82), family history of OA [OR 0.47; 95% CI 0.37–0.62], diabetes [OR 2.78; 95% CI 2.17–3.56], hypertension [OR 0.35; 95% CI 0.26–0.45] were significantly associated with the percentage of the WOMAC index score using the Chi-square test analysis (P<0.05). Therefore, the WOMAC index showed higher diagnostic precision with a statistically significant association [OR 9.31 CI 6.90–12.81] with a P< 0.0001. Conclusion KOA is more common in older, obese people who have reached the age of 50 in the Asir region, and it is more prevalent in women. Alarms the need for appropriate awareness programs for better disease prevention and health outcomes for the benefit of the community through general public health programs.

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Acute osteomyelitis in children in Ibadan, Nigeria. Is surgical decompression necessary?

Cited by 5 publications

References 13 publications

Variations and characteristics of the various clinical phenotypes in a cohort of Nigerian sickle cell patients

Variations and characteristics of the various clinical phenotypes in a cohort of Nigerian sickle cell patients

Childhood Pyogenic Osteomyelitis in Abakaliki, South East Nigeria

An evaluation of knee osteoarthritis pain in the general community—Asir region, Saudi Arabia

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