ACUTE ORAL TOXICITY STUDY OF ROOT METHANOL EXTRACT OF Goniothalamus lanceolatus Miq. AND ITS ISOLATED BIOACTIVE COMPOUND (PARVISTONE D) IN MURINE MODEL
Abstract:Goniothalamus lanceolatus Miq. is widely used by the indigenous people of Sarawak, Malaysia as a folk remedy to treat various ailments including skin diseases, cold, and fever. A previous study reported that the root methanol extract, and parvistone D, an active compound of the plant, showed promising in vitro antiplasmodial activity against Plasmodium parasites. However, there is limited data reporting on its toxicological profile. Thus, this study aims to evaluate the potential toxicity of root methanol extr… Show more
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