Acute-Onset Floaters and Flashes

Hollands, Hussein; Johnson, Davin; Brox, Anya C.; Almeida, David R.P.; Simel, David L.; Sharma, Sanjay

doi:10.1001/jama.2009.1714

Cited by 104 publications

(33 citation statements)

References 28 publications

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“…A significant proportion of patients with acute PVD complain of monocular floaters [5]. In the present study, we therefore considered the onset of floaters to be a potential sign of acute PVD.…”

Section: To the Editormentioning

confidence: 99%

Subjective Signs of Rhegmatogenous Retinal Detachment Associated With Acute Posterior Vitreous Detachment

Sato

Nishimura

2013

J Clin Med Res

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Section: To the Editormentioning

confidence: 99%

Subjective Signs of Rhegmatogenous Retinal Detachment Associated With Acute Posterior Vitreous Detachment

Sato

Nishimura

2013

J Clin Med Res

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“…The liquefied vitreous fluid may leak out from the vitreous body and make posterior vitreous surface separated from retina, leading to posterior vitreous detachment (PVD). The prevalence of eye floaters in the general population increase from 24% in adults aged 50 to 59 years to 87% among those aged 80 to 89 years [ 1 ]. In 14% cases, myodesopsia is associated with a retinal tear and if not treated properly 33% to 46% of them may lead to retinal detachment [ 1 , 2 ].…”

Section: Introductionmentioning

confidence: 99%

Doctor-Shopping Behavior among Patients with Eye Floaters

Tseng

Chen

2015

IJERPH

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Patients suffering from eye floaters often resort to consulting more than one ophthalmologist. The purpose of this study, using the Health Belief Model (HBM), was to identify the factors that influence doctor-shopping behavior among patients with eye floaters. In this cross-sectional survey, 175 outpatients who presented floaters symptoms were enrolled. Data from 143 patients (77 first time visitors and 66 doctor-shoppers) who completed the questionnaire were analyzed. Descriptive and logistic regression analyses were performed. We found that women and non-myopia patients were significantly related with frequent attendance and doctor switching. Though the HBM has performed well in a number of health behaviors studies, but most of the conceptual constructors of HBM did not show significant differences between the first time visitors and true doctor-shoppers in this study. Motivation was the only significant category affecting doctor-shopping behavior of patients with eye floaters.

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“…3,4 Regardless of the specific pathophysiologic mechanism, any exogenous risk factor for acute rhegmatogenous retinal detachment would also likely increase the rate of symptomatic retinal breaks, as causative break-related symptoms commonly precede detachment and urgent treatment of these lesions reduces the risk of retinal detachment from approximately 50% to less than 5%. 20 Therefore, to investigate this hypothesis, we conducted a population-based cohort study to investigate whether oral fluoroquinolone prescriptions were associated with an increased risk of rhegmatogenous retinal detachment and symptomatic retinal tears.…”

Section: Introductionmentioning

confidence: 99%

Oral Fluoroquinolones and the Incidence of Rhegmatogenous Retinal Detachment and Symptomatic Retinal Breaks

et al. 2014

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Objective To examine whether oral fluoroquinolone antibiotics are associated with an increase in subsequent rhegmatogenous retinal detachment and symptomatic retinal breaks in a large, population-based cohort. Design Population-based cohort study Participants and Controls Adult residents of Olmsted County, Minnesota who were prescribed oral fluoroquinolone medications from 1/01/03 – 6/30/11. Comparison cohorts consisted of patients prescribed oral macrolide and β-lactam antibiotics during the study period. Methods Procedure codes were used to identify retinal detachment repair and prophylaxis procedures occurring within 1 year of prescription dates. Travel clinic, pro re nata, and self-treatment prescriptions were excluded. Patients with tractional retinal detachment, previous retinal detachment repair, endophthalmitis, and necrotizing retinitis were excluded, as were those with intraocular surgery or severe head/eye trauma ≤ 90 days prior to the procedure. Main Outcome Measures Rates of retinal detachment repair and prophylaxis procedures within 7, 30, 90, and 365 days of the first prescription were calculated and compared between antibiotic prescription cohorts using Chi-square tests. Retinal detachment repair rates were also compared to the expected Olmsted County, Minnesota rates using the one-sample log rank test. Results Oral fluoroquinolones were prescribed for 38,046 patients (macrolide n=48,074, β-lactam n=69,079) during the study period. Retinal detachment repair procedures were performed within 365 days of the first prescription in 0.03% (95% confidence interval [CI] 0.01–0.06%) of the fluoroquinolone, 0.02% (95% CI 0.01–0.03%) of the macrolide, and 0.03% (95% CI 0.02–0.05%) of the β-lactam cohorts (p>0.05). Retinal detachment prophylaxis procedures for symptomatic retinal breaks were performed within 365 days of the first prescription in 0.01% (95% CI 0.00–0.03%) of the fluoroquinolone, 0.02% (95% CI 0.01–0.04%) of the macrolide, and 0.02% (95% CI 0.01–0.04%) of the β-lactam cohorts (p>0.05). Similar comparisons of treatment rates within 7, 30, and 90 days of the first prescription were all non-significant between cohorts. Post-fluoroquinolone retinal detachment repair rates were similar to expected rates (36.8 per 100,000/year vs 28.8 per 100,000/year for age- and sex-matched historical rates, p = 0.35). Conclusions Oral fluoroquinolone use was not associated with an increased risk of rhegmatogenous retinal detachment or symptomatic retinal breaks in this population-based study.

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Acute-Onset Floaters and Flashes

Cited by 104 publications

References 28 publications

Subjective Signs of Rhegmatogenous Retinal Detachment Associated With Acute Posterior Vitreous Detachment

Subjective Signs of Rhegmatogenous Retinal Detachment Associated With Acute Posterior Vitreous Detachment

Doctor-Shopping Behavior among Patients with Eye Floaters

Oral Fluoroquinolones and the Incidence of Rhegmatogenous Retinal Detachment and Symptomatic Retinal Breaks

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