Acute oedema associated with risperidone use: a report

Thakur, Arpita; Niranjan, Vijay; Rastogi, Pali; Razdan, Ramghulam

doi:10.1136/gpsych-2020-100203

Cited by 3 publications

(3 citation statements)

References 7 publications

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“…Other side effects of psychotropics reported in case reports involving patients with ATPD include EPS with aripiprazole,[ 213 ] neuroleptic malignant syndrome (NMS) with olanzapine,[ 214 215 ] aripiprazole,[ 216 ] and injection haloperidol,[ 217 ] NMS in the absence of raised creatinine phosphokinase levels,[ 218 ] psoriasis with olanzapine,[ 219 ] acute pedal edema,[ 220 ] and angioneurotic edema[ 221 ] with risperidone, hirsutism with olanzapine,[ 222 ] cognitive decline amounting to dementia in an elderly patient of ATPD after being treated with olanzapine, lorazepam, and trihexyphenidyl. [ 223 ]…”

Section: Resultsmentioning

confidence: 99%

Acute and transient psychotic disorders: A review of Indian research

Grover,

Kathiravan

2023

Indian Journal of Psychiatry

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Background: Acute and transient psychotic disorder (ATPD) was recognized as separate from other psychotic disorders and described in the International Classification of Diseases (ICD) tenth revision for the first time. A lot of research on ATPD has been conducted in India over the last six decades, but a review focusing exclusively on Indian research on ATPD is not available. Aim: This paper aims to review the literature on ATPD emerging from India. Methodology: A combination of search terms “Acute and Transient Psychosis,” “acute psychosis,” “non-affective psychosis,” “non-affective psychotic disorder,” “reactive psychosis,” “first-episode psychosis,” and “India” were searched on various search engines like PUBMED, Medknow, Hinari, and Google Scholar. We also did a hand search for additional relevant articles, including published abstracts of the Indian Journal of Psychiatry from 2007 to 2023. Relevant papers were selected. Results: The prevalence of ATPD varies across different study settings, and it tends to have an abrupt to acute onset, and is primarily associated with stress. Few studies have assessed the subtypes of ATPD, and symptom profile has been inconsistently reported. There is a lack of trials on the effectiveness or efficacy of antipsychotics in ATPD patients. In a large proportion of patients initially diagnosed with ATPD, the diagnosis remains stable, with recurrence varying from 10% to 46.6% based on the duration of follow-up. Conclusion: There is a need for more multicentric studies, studies with larger sample sizes, and consistency in data about risk factors. There is a need to evaluate symptom profile, course, outcome, and treatment outcomes in patients with ATPD using validated instruments to improve our understanding. Further, there is a need for comparative studies to evaluate the risk factors for ATPD.

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Section: Resultsmentioning

confidence: 99%

Acute and transient psychotic disorders: A review of Indian research

Grover,

Kathiravan

2023

Indian Journal of Psychiatry

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“…19 The antipsychotics risperidone and aripiprazole are widely studied with respect to their impact on multiple aspects including the influence on hepatic function, renal function, the impact of the drug in the liver, and several other aspects. 2,20 Both of the following drugs have proven to be safe for clinical use under prescribed doses and conditions. In the following trial, the impact of aripiprazole and Risperidone has been studied in the levels of thyroid hormones including T3, T4, and TSH.…”

Section: Discussionmentioning

confidence: 99%

Inflammatory Thyroid Changes Following Serotonin Receptor Blocking in Experimental Rats

Dawood¹,

Aldabbagh²,

Alsarraf³

2023

Pharmacogn J.

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“…Further, the apparent side effects of Aripiprazole represented that an unusual antipsychotic drug is called Abilify (aripiprazole). 18 Some of the most common adverse effects of Abilify include headache, nausea, and vomiting. antipsychotics.…”

Section: Discussionmentioning

confidence: 99%

Pathophysiological Electrolyte Changes Connoted via Antagonism of Serotonin Receptor in Experimental Animals

Mahmood¹,

Younes²,

Saarti³

2022

Pharmacogn J.

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Background: Atypical antipsychotics are a subclass of antipsychotics that have emerged primarily since the 1970s for the treatment of psychiatric disorders. They are sometimes referred to as second-generation antipsychotics (SGAs). Several atypical antipsychotics have received regulatory approval for the treatment of disorders such as bipolar disorder, schizophrenia, irritability in autism, and as adjunctive treatment for major depressive disorders. Objectives: The purpose of the following study was to evaluate the effect of two widely known atypical antipsychotics, aripiprazole, and risperidone, on pathophysiological fluctuations in electrolytes. Several other studies were based on the following ideas, which brought a variety of different perspectives. As can be seen in the following evaluation, although atypical antipsychotics reduce the chance of extrapyramidal symptoms, it leads to impairment of renal function and destruction of renal histo-morphology. Materials and Methods: Thirty rats (10 per group) were used for this study, control group received normal saline, aripiprazole group received 10mg/kg//day, and risperidone group received 20mg/kg//day. The duration of therapy was long up to 3 months. Results: the results confirmed that both drugs reduced plasma sodium and chloride concentration with no effects on plasma potassium and calcium concentration. Moreover, the histomorphology at microscopic level shown no defects after 3 months of therapy. Conclusion: the outcome confirmed no deleterious defects associated with aripiprazole and risperidone when used for 3 months.

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Acute oedema associated with risperidone use: a report

Cited by 3 publications

References 7 publications

Acute and transient psychotic disorders: A review of Indian research

Acute and transient psychotic disorders: A review of Indian research

Inflammatory Thyroid Changes Following Serotonin Receptor Blocking in Experimental Rats

Pathophysiological Electrolyte Changes Connoted via Antagonism of Serotonin Receptor in Experimental Animals

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