Acute Non-Rheumatic Myopericarditis: A Follow-up Study

Bergström, K; Erikson, Uno; Nordbring, Folke; Nordgren, Bengt; Parrow, Anders

doi:10.3109/inf.1970.2.issue-1.02

Cited by 32 publications

(12 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Of the five patients with pathologic physical findings, only Cases 5 and 14 showed low exercise tolerance. Similar observations were made by Bergstrom et al (2). By contrast, Bengtsson & Lamberger (3) reported good correlation between the patients' symptoms, ECG changes and reduction of working capacity.…”

Section: Discussionsupporting

confidence: 46%

See 1 more Smart Citation

Acute Myopericarditis

Sanner¹,

Sigurðsson²,

Gislasson³

et al. 1976

Upsala Journal of Medical Sciences

View full text Add to dashboard Cite

A follow-up study was made of 29 patients aged 21 to 45 years, some 15-158 months after acute myopericarditis. The mean follow-up period was 72.9 months. The follow-up investigation included recording of history, physical examination, laboratory tests, radiologic examination of the heart and lungs and electrocardiography. All hut one of the patients were fit for fulltime work. Nine had residual cardiac symptoms, but the physical examination was negative in all but 2 of them. One patient had chronic cardiac insufficiency and hepatic enlargement. Another had sinus tachycardia and cardiac enlargement of moderate degree and impaired working capacity in relation to heart size. Cardiac murmurs without clinical significance were audible in three cases. The resting ECG was pathologic in only 6 cases. Orthostatic ECG evoked ECG abnormalities in 6 more cases. Exercise tolerance tests showed reduced working capacity in relation to heart volume in 5 of the 29 cases (17%). Four of these 5 patients had cardiac enlargement. There was thus good correlation between increase in heart volume and reduction of physical capacity. The prognosis in regard to cardiac function was good, as was also found in other comparable series in which the observation time was somewhat shorter.

show abstract

Section: Discussionsupporting

confidence: 46%

“…Some reports have recently been published on the incidence and course of acute myopericarditis (11,3,7,2,6). The prognosis of acute myopericarditis in regard to cardiac function is considered to be good, however, a few deaths and occasional cases of chronic cardiac insufficiency have been reported (11,16,13).…”

Section: Introductionmentioning

confidence: 99%

Acute Myopericarditis

Sanner¹,

Sigurðsson²,

Gislasson³

et al. 1976

Upsala Journal of Medical Sciences

View full text Add to dashboard Cite

show abstract

“…This low percentage of enteroviral myocarditis is one of the most conspicuous features of the present study since in most myocarditis studies the enteroviruses are the predominant aetiologies (except for studies during epidemics of other infectious diseases) [6,7,[16][17][18][19][20] . The primary focus of this study was not on microbial diagnostics, and so several routine diagnostic methods were employed during the course of the study.…”

Section: See Page 1020 For the Article To Which This Editorial Refersmentioning

confidence: 91%

The incidence and epidemiology of myocarditis

Friman

1999

European Heart Journal

View full text Add to dashboard Cite

“…A review of the worldwide literature reveals at least 7 fatal (11-13) and 59 non-fatal cases of post-vaccinial myocarditis among adults (13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25) using autopsy, symptoms, and/or electrocardiogram (ECG) changes to diagnose myocarditis and/or pericarditis. Estimates of incidence range from as high as 2% to 3%, based on the number of Swedish military recruits with asymptomatic T-wave changes after vaccination (14,20), to 1 in 10,000, a number calculated in a 1983 Finnish study on the basis of 12 reported cases divided by the number of military vaccinees in that interval (21).…”

Section: Cardiac Complications Of Smallpox Vaccinationmentioning

confidence: 99%

Smallpox vaccination and myopericarditis: a clinical review

Cassimatis

Atwood

Engler

et al. 2004

Journal of the American College of Cardiology

169

131

View full text Add to dashboard Cite

Smallpox is a devastating viral illness that was eradicated after an aggressive, widespread vaccination campaign. Routine U.S. childhood vaccinations ended in 1972, and routine military vaccinations ended in 1990. Recently, the threat of bioterrorist use of smallpox has revived the need for vaccination. Over 450,000 U.S. military personnel received the vaccination between December 2002 and June 2003, with rates of non-cardiac complications at or below historical levels. The rate of cardiac complications, however, has been higher than expected, with two confirmed cases and over 50 probable cases of myopericarditis after vaccination reported to the Department of Defense Smallpox Vaccination Program. The practicing physician should use the history and physical, electrocardiogram, and cardiac biomarkers in the initial evaluation of a post-vaccination patient with chest pain. Echocardiogram, cardiac catheterization, magnetic resonance imaging, nuclear imaging, and cardiac biopsy may be of use in further workup. Treatment is with non-steroidal anti-inflammatory agents, four to six weeks of limited exertion, and conventional heart failure treatment as necessary. Immune suppressant therapy with steroids may be uniquely beneficial in myopericarditis related to smallpox vaccination, compared with other types of myopericarditis. If a widespread vaccination program is undertaken in the future, many more cases of post-vaccinial myopericarditis could be seen. Practicing physicians should be aware that smallpox vaccine-associated myopericarditis is a real entity, and symptoms after vaccination should be appropriately evaluated, treated if necessary, and reported to the Vaccine Adverse Events Reporting System.

show abstract

Acute Non-Rheumatic Myopericarditis: A Follow-up Study

Cited by 32 publications

References 17 publications

Acute Myopericarditis

Acute Myopericarditis

The incidence and epidemiology of myocarditis

Smallpox vaccination and myopericarditis: a clinical review

Contact Info

Product

Resources

About