Acute necrotizing esophagitis: Another case

Marie-Christine, Benhaim-Iseni; Pascal, B; Jean-Pierre, Petite

doi:10.1016/0016-5085(91)90511-i

Cited by 23 publications

(3 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… CAD, coronary artery disease; DM, diabetes mellitus; HTN, hypertension; H 2 , histamine 2 ; UGI, upper gastrointestinal tract. †Six patients from Mayo Clinic and 46 patients from the literature 1–24 ‡Except for age data, all data are presented as number of patients and percentage of patients for whom data were available. …”

Section: Resultsmentioning

confidence: 99%

“…To identify cases of black esophagus reported in the English‐language literature, the Ovid MEDLINE database was searched using the terms ‘black esophagus’ and ‘acute esophageal necrosis’ for the years 1963 through 2003. The search identified 46 cases of black esophagus 1–24 …”

Section: Methodsmentioning

confidence: 99%

“…The reported incidence of black esophagus in patients undergoing upper endoscopy ranges from 0.0125% to 0.2% 1,2 . Proposed causes of acute esophageal necrosis include ischemia, 3 lye ingestion, 3 microbial infection related to a nasogastric tube, 3 anticardiolipin antibody syndrome, 4 herpes simplex esophagitis, 5 diabetic ketoacidosis, 6 severe vomiting, 7 acute gastric outlet obstruction with massive gastroesophageal reflux, 8 Lactobacillus acidophilus infection, 9 acute caustic injury from detergent in the endoscope, 10 antibiotics, 11 Stevens–Johnson syndrome, 12 and hypothermia 13 . Nevertheless, what is known about black esophagus is based primarily on case reports and small case series.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Black esophagus: report of six cases and review of the literature, 1963–2003

Grudell¹,

Mueller²,

Viggiano

2006

Diseases of the Esophagus

119

View full text Add to dashboard Cite

Black esophagus is the uncommon endoscopic finding of extensive black discoloration of the esophageal mucosa, usually from acute esophageal necrosis. Six cases of black esophagus were seen at Mayo Clinic (Rochester, Minnesota, USA) from 1997 through 2003, and 46 cases were reported in the English-language literature from 1963 through 2003. We studied the demographics, clinical features, and outcomes of these 52 cases of black esophagus. Age and sex were known for 50 patients: the mean (SD) age was 65 years (19), and 42 patients (84%) were men. Symptoms were known for 51 patients: the most common symptom was upper gastrointestinal tract bleeding, occurring in 40 patients (78%). All 52 patients had at least one comorbid condition (with most having two or more), including duodenal ulcer in 17 (33%), cancer in 15 (29%), renal insufficiency in 15 (29%), and diabetes mellitus in 14 (28%). The suspected cause of black esophagus was reported for 40 patients: ischemia in 22 (55%); massive gastroesophageal reflux in seven (18%); and esophageal infection (Lactobacillus acidophilus, herpes simplex, Candida albicans) in four (10%). Most patients received supportive therapy, particularly acid suppression therapy. Of the 47 patients for whom outcomes were known, 17 (36%) died. There were no statistically significant differences between survivors and non-survivors. Black esophagus typically occurs in older men with at least one comorbid condition; a substantial number of patients die. Although the underlying mechanism leading to black esophagus is unknown, clinicians caring for patients with black esophagus should focus on optimizing perfusion, minimizing acid reflux, and treating esophageal infection if present.

show abstract