Acute myocardial infarction without significant coronary stenoses associated with endogenous subclinical hyperthyroidism

Focus on Autoimmune Myocarditis in Graves' Disease: A Case-Based Review

“…The proposed mechanisms responsible for coronary events in hyperthyroidism include a hypercoagulable and hypofibrinolytic state as well as hyperthyroidism-associated coronary vasospasm and increased myocardial oxygen demand (79,80). Although many hyperthyroidism patients with typical chest pain, elevated levels of myocardial injury, and abnormal electrocardiograms have been diagnosed with myocardial infarction (MI) in the past, most of these patients are then shown to be free of coronary disorder as documented by both angiographic and postmortem studies (81)(82)(83)(84). Thus, an important question haunts us as to whether these patients really suffered from myocardial infarction.…”

A case of myocardial infarction in a young female with subclinical hyperthyroidism

“…In particular, thyrotoxicosis is well known as the cause of sudden unexpected death [4][5][6][7][8]. Recently, several lines of accumulating evidence demonstrated that thyroid dysfunction increased the risk of cerebral vascular diseases [9] and ischemic heart diseases [10][11][12]. Herewith, we report a case of acute myocardial infarction in a young female with untreated hyperthyroidism.…”

“…However, in spite of the absence of fixed coronary artery diseases, thyrotoxicosis is closely associated with acute myocardial infarction. Patanè et al reported a case of acute myocardial infarction without coronary stenosis in patients with hyperthyroidism [11,12]. They also reported a case of acute myocardial infarction with myocardial bridge [21].…”

Cardiovascular system and endogenous subclinical hyperthyroidism treatment: The time has come

“…Subclinical hyperthyroidism could represent a potential hypercoagulable state which might augment the already existing risk for atheroscleroic complications [49] and it contributes to increased thromboembolic risk [19,63]. Moreover coronary vasoconstriction [66] and recently, acute myocardial infarction without significant coronary stenoses [53,61,67] and recurrent acute ⁎ Tel. :+39 3402783962.…”