Acute myocardial infarction in a Chinese patient with haemophilia A and risk factors for coronary artery disease: a case report with autopsy

Abstract

However, due to the possibility of further bleeding, FEIBA was administered FEIBA was administered every 12 h in doses of 100 U kg )1 for 3 days and then every 24 h for 4 days, but we decided not to operate. On day 4, the patientÕs condition improved. During the next few days, the amount of fluid in the left lung decreased. From day 16, rehabilitation was started and FEIBA was administered prophylactically for 2 weeks. The patient was discharged from hospital 6 weeks after the episode and FVIII inhibitor level was 28 UB mL )1 . Six months after the episode a CT scan showed marked improvement and 12 months after the episode a chest radiograph was normal (Fig. 7). To sum up cases of bleeding into the pleural cavity are rare in literature (1-5). Each of the three cases of haemothorax we describe above was treated in a different way. Replacement therapy was used for the first patient, thoracenthesis was carried out for case 2, while surgery was not performed for case 3 due to the presence of inhibitor. Results 12 months after discharge from hospital were similar in all three cases. We consider that early physiotherapy is essential and patients with coagulation abnormalities and haemothorax should be managed individually depending on their general condition, results of diagnostic tests and accessibility of clotting factor concentrates. Fig. 7. Chest radiograph was normal.

Discrepant ratios of arterial vs. venous thrombosis in hemophilias A and B as compared to FVII deficiency

“…The same is true for the patients with FVII deficiency and thrombosis . Only new cases together with exceptional reports which had escaped our previous inquiries are referenced in this article . However, the calculations were carried out on the entire pool of patients.…”

Consensus Review of the Treatment of Cardiovascular Disease in People With Hemophilia A and B

“… 26 Chest pain syndromes may indicate myocardial ischemia in PWH, especially in those PWH with cardiovascular risk factors or when pain occurs after administration of factor replacement or bypassing agents. 79 …”

Acute coronary syndrome management in hemophiliacs: How to maintain balance?: A review

“…In China, it is estimated that there are 60,000 to 130,000 patients with hemophilia, [36] but only 4 cases have been recorded. Guo Yang et al [37] reported the first case of a hemophiliac patient who died after suffering from STEMI without receiving antithrombotic or PCI therapy. In 2016, 2 cases were reported in which patients with unstable angina underwent PCI and postoperative antithrombotic therapy without significant complications.…”