Acute Myocardial Infarction Complicating Coronavirus Infection (Case Report)

Abstract

Coronavirus infection caused by the SARS-CoV-2 virus is a multifaceted disease due to generalized vascular endothelial damage. Endothelial damage also underlies COVID-associated coagulopathy.The paper presents a case of coagulopathy causing myocardial infarction in a 43-year-old patient with no history of coronary disease. We have reviewed the available literature for the pathophysiological rationale of the assumed possibility of coronary thrombosis resulting from coagulopathy with the intact intima of the coronary arteries.Conclusion. The present observation of coronary thrombosis with radiographically intact coronary artery intima confirms the important role of coronavirus infection in triggering endothelial dysfunction. Currently, the most effective strategy for this type of coronary lesions is the use of anticoagulants and antiplatelet agents along with ECG, echocardiography and troponin level monitoring.

Spectrum of Thrombotic Complications in Fatal Cases of COVID-19: Focus on Pulmonary Artery Thrombosis In Situ

“…When comparing the frequency of the studied parameters in the groups of patients with and without thrombotic complications (Table 5), we found that patients with thrombotic complications had a longer hospital stay (11)(12)(13)(14)(15)(16) The statistically significant results are highlighted in bold. 1 Student's t-test; 2 Mann-Whitney U test, 3 Chi-square test; 4 Fisher's exact test; 5 Fisher-Freeman-Halton exact test.…”

“…Although COVID-19 is a respiratory disease and the lung is the target organ of SARS-CoV-2, extrapulmonary complications have been reported in both clinical and pathological studies. Cardiovascular, neurological, gastrointestinal, renal, hepatic, and other complications have been described [ 2 , 3 ]. Since early 2020, there have been increasing reports of hypercoagulable state, especially leading to venous thromboembolism (VTE), in patients with COVID-19 [ 4 , 5 , 6 ].…”