Acute myeloid leukemia presenting with multiple breast and skin myeloid sarcomas: A case report

Khatib, Yumna; Farfoura, Heba; Haddad, Hussam; Mrie, Lina; Al-Rabie, Kamal; Ma’koseh, Mohammad

doi:10.52768/2766-7820/1045

J Clin Images Med Case Rep

2021

DOI: 10.52768/2766-7820/1045

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Acute myeloid leukemia presenting with multiple breast and skin myeloid sarcomas: A case report

Yumna Khatib¹,

Heba Farfoura²,

Hussam Haddad³

et al.

Abstract: We report a case of 63-year old female who presented to breast imaging unit with multiple bilateral breast masses. Her past history was significant for left thigh mass. Mammogram and breast ultrasound revealed multiple bilateral breast masses. Ultrasound guided true-cut biopsy from right breast mass was consistent with myeloid sarcoma. Bone marrow biopsy showed acute myeloid leukemia (FAB-M5B) evolving on the background of Chronic Myelomonocytic Leukemia (CMML).

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Renal biopsy reports in nephritic syndrome: Update

Taheri¹

2022

WJN

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BACKGROUND Nephritic syndrome (NiS) is a major indicator of serious renal diseases necessitating kidney biopsies for histopathological evaluations, but due to the lack of comprehensive reviews in the literature, the current understanding of the syndrome and its significance is limited. AIM To collect all the evidence retrievable from the literature on the diagnoses made on the renal biopsies performed for NiS as the indication to the procedure. METHODS A literature search was conducted to find studies reporting final diagnoses on renal biopsies in NiS patients. Data were pooled and analyzed with stratifications on age and regions. Meta-analyzes were performed using Stata v.9. RESULTS Overall, 26414 NiS patients from the total number of 96738 kidney biopsy diagnoses reported by 47 studies from 23 countries from all continents (except sub-Saharan Africa) were found and analyzed. NiS was the indication for renal biopsy in 21% of the patient populations across the reviewed studies. Immunoglobulin A (IgA) nephropathy was the single most frequent diagnosis in these patients (approximately 38%) followed by lupus nephritis (approximately 8%) and Henoch Schönlein purpura (approximately 7%). IgA nephropathy was the most frequent diagnosis reported for the NiS patients from the East Asia, comprising half of all the cases, and least prevalent in South Asia. Considering the age subgroups, adult ( vs pediatric or elderly) patients were by far the most likely age group to be diagnosed with the IgA nephropathy. A myriad of such regional and age disparities have been found and reported. CONCLUSION As the indication for renal biopsy, NiS represents a very distinctive epidemiology of final renal disease diagnoses compared to the other major syndromes.

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Renal biopsy reports in nephritic syndrome: Update

Taheri¹

2022

WJN

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Acute myeloid leukemia presenting with multiple breast and skin myeloid sarcomas: A case report

Cited by 1 publication

References 14 publications

Renal biopsy reports in nephritic syndrome: Update

Renal biopsy reports in nephritic syndrome: Update

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