Acute myelogenous leukemia presenting as facial nerve palsy. A case report

Levy, R; Har‐El, Gady; Segal, Karl; Sidi, J

doi:10.1016/s0165-5876(86)80056-8

Cited by 21 publications

(13 citation statements)

References 9 publications

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“…Eight children with facial palsy as a presenting symptom of AML were reported from 1984 to 2006 (Table 1), [4][5][6][7][8][9][10][11] with ages ranging from 11 months to 17 years. Although there are generally no peaks of incidence for AML in children, most patients tended to be older than the present case.…”

Section: Discussionmentioning

confidence: 99%

Facial palsy as an unusual presenting symptom associated with acute myeloid leukemia

Kubota

Ozeki

Hori

et al. 2014

Pediatrics International

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Extramedullary infiltration is common in acute myeloid leukemia (AML) patients. Although AML can cause neurological symptoms, especially when associated with extramedullary infiltration, a presenting manifestation of facial palsy is rare. We report on a 1-year-old boy who developed right facial palsy. Detailed examination led to a diagnosis of AML (French-American-British classification M1). Magnetic resonance imaging enhanced with gadolinium-diethylenetriamine penta-acetic acid showed abnormal enhancement of the right facial nerve, which disappeared after chemotherapy. AML should be considered as a differential diagnosis of facial palsy. Enhanced magnetic resonance imaging may be useful for diagnosing facial palsy associated with AML and for evaluating treatment outcome.

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Section: Discussionmentioning

confidence: 99%

Facial palsy as an unusual presenting symptom associated with acute myeloid leukemia

Kubota

Ozeki

Hori

et al. 2014

Pediatrics International

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“…Bone marrow aspiration and lumbar puncture should be performed. Unless these tests are performed, mastoid bone surgery should be avoided [10]. The brain and the temporal bone should be examined with high-resolution CT or MRI.…”

Section: Discussionmentioning

confidence: 99%

Bilateral Facial Nerve Paralysis Secondary to Acute Myelogenous Leukemia

Güngör¹,

Cincik²,

Poyrazoğlu³

et al. 2002

Otorhinolaryngol Nova

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Bilateral facial paralysis is a rare condition. We present a case of acute myeloblastic leukemia manifesting itself in bilateral hearing loss and bilateral facial paralysis. We suspected systemic disease because of the abnormal blood cell count of the case. The diagnosis of leukemia was made with histological examination of a bone marrow aspirate. Computed tomography and gadolinium-enhanced magnetic resonance imaging scans revealed bilateral infiltration of the mastoid bones, middle ears and facial nerves. One should always remember that bilateral facial paralysis may be the first sign of a life-threatening illness. If infiltration is observed in the air-filled cells of the mastoid bone, before emergency surgery is planned, the possibility of leukemic infiltration should be considered.

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“…Haematological disorders, such as leukaemia,9 12 haemophilia,13 may rarely present with FNP. Acute onset FNP has also been reported in cases of malignant hypertension 14.…”

Section: What Should You Cover In the History?mentioning

confidence: 99%

“…Full blood count to rule out leukaemia,9 12 borrelia serology in endemic areas for Lyme disease17 should be done as indicated.…”

Section: What Management Should You Provide?mentioning

confidence: 99%

15 minute consultation: a structured approach to the management of facial paralysis in a child

Malik

Joshi

Green

et al. 2012

Arch Dis Child Educ Pract Ed

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Acute myelogenous leukemia presenting as facial nerve palsy. A case report

Cited by 21 publications

References 9 publications

Facial palsy as an unusual presenting symptom associated with acute myeloid leukemia

Facial palsy as an unusual presenting symptom associated with acute myeloid leukemia

Bilateral Facial Nerve Paralysis Secondary to Acute Myelogenous Leukemia

15 minute consultation: a structured approach to the management of facial paralysis in a child

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