Acute Multiple Cerebral Infarction in a Patient with an Accessory Mitral Valve

Abstract

A 96-year-old woman developed hemiparesis 2 weeks after orthopedic surgery. Magnetic resonance imaging revealed multiple cerebral infarctions in the bilateral hemisphere. Transthoracic echocardiography revealed a mobile structure attached to the anterior mitral leaflet that protruded toward the left ventricular outflow tract. The structure was identified as an accessory mitral valve. Doppler echocardiography showed that there was no significant left ventricular outflow obstruction. This is a rare case of a silent accessory mitral valve that was detected after multiple cerebral infarctions.

Alteplase improves acute cerebral infarction by improving neurological function and cerebral hemodynamics

“…The occurrence and development of acute cerebral infarction are influenced by coagulation and inflammatory factors and several other cell factors, including coagulation factor VIII (FVIII), von Willebrand factor (vWF), tumor necrosis factor-α (TNF-α), and interleukin-1β (IL-1β), among others. (Bong et al 2017;Misumi et al 2017) Reportedly, stromal cell-derived factor-1 (SDF-1) and claudin-5 closely correlated to acute cerebral infarction (He et al 2017). For instance, SDF-1, a protein within the family of chemotactic factors, can induce the migration of CD34 hematopoietic CONTACT Hongbin Liu oym79r@163.com Department of Neurology, the Third Affiliated Hospital of Qiqihar Medical University, No.27, Taishun Street, Tiefeng District, Qiqihar, Heilongjiang, 161000, People's Republic of China stem/progenitor cells.…”