Acute Mortality and Changes in Body-weight of Mice after Partial-body Irradiation with X-rays and Fast Neutrons

Abstract

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A Mathematical Model of the Human Small Intestine Following Acute Radiation and Burn Exposures

“…Time after irradiation (days) Cells per column (normalized) Experiment q 2.38 Gy (Rijke 1977) 3.17 Gy (Galjaard 1969) 4.34 Gy (Matsuzawa 1973) 5.55 Gy (Galjaard 1969) 5.55 Gy (Rijke 1977) Crypt cells (0 to 6 Gy) 2.38 Gy (Rijke 1977) 4.34 Gy (Matsuzawa 1973) 4.36 Gy (Quastlar 1956) 5.55 Gy (Rijke 1977) Villus cells (0 to 6 Gy) Time after irradiation (days) Cells per column (normalized) Experiment q 6.08 Gy (Potten 1990) 7 Gy (Kononenko 1969) 7 Gy (Smirnova 2010) 7.6 Gy (Patel 2012) Crypt cells (6 to 8 Gy) Time after irradiation (days) Cells per column (normalized) Experiment q 7 Gy (Kononenko 1969) 7 Gy (Smirnova 2010) 7.6 Gy (Patel 2012) Villus cells (6 to 8 Gy) Figure 3.4: Murine data from acute radiation experiments (6 to 8 Gy). (Sato 1972) 9 Gy (Kononenko 1969) 17.34 Gy (Matsuzawa 1973) 25 Gy (Sherman 1959) Crypt cells (8 to 25 Gy) (Sato 1972) 9 Gy (Kononenko 1969) 17.34 Gy (Matsuzawa 1973) 17.43 Gy (Quastlar 1956) 25 Gy (Sherman 1959) Villus cells (8 to 25 Gy) Variability in data must be considered when comparing the model to the data. Measurement variability can be expected as we have collected data from studies with diverse experimental procedures.…”