Acute Lymphoblastic Leukemia with Infective Endocarditis Presented with Unusual Intracardiac Mass

Tabaei, Ali Sadeghpour; Koochakzadeh, Leili; Khorgami, Mohammadrafie; Tabaei, Sepehr Sadeghpour

doi:10.1155/2017/1528416

Cited by 1 publication

(1 citation statement)

References 17 publications

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“…Tabaei et al report a similar case of a 6-year-old boy with ALL that developed IE that eventually required surgical resection. [30] e most common location of brainstem infections occur in the pons region followed by the midbrain and medulla oblongata, respectively. Multiple BAs vary in the literature and have been reported in up to 50% of cases in children.…”

Section: Discussionmentioning

confidence: 99%

Multiple Abscesses in the Frontal, Temporal and Brainstem regions in a 4.5-year-Old Girl- An Illustrative Case Report

Mohammad¹,

Crimmins²

2023

Surgical Neurology International

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Background: Brainstem located abscesses are rare in the pediatric population. Diagnosis of brain abscess can be challenging as patients may present with nonspecific symptoms and the classical triad of headache, fever, and focal neurological deficit is not always present. Treatment can be conservative or a combination of surgical intervention with antimicrobial therapy. Case Description: We present the first case of a 4.5-year-old girl with acute lymphoblastic leukemia that developed infective endocarditis (IE) and subsequently developed 3 suppurative collections (frontal, temporal, and brainstem). The patient had negative cerebrospinal, blood, and pus culture growth and subsequently underwent burr-hole drainage of the frontal and temporal abscesses with a 6-week course of intravenous antibiotic therapy with an uneventful postoperative course. At 1 year, the patient is left with minor right lower limb hemiplegia and no cognitive sequelae. Conclusion: The decision to surgically intervene for brainstem abscesses is dependent on surgeon and patient factors including the presence of multiple collections, midline shift, the aim of source identification in sterile cultures, and the patient’s neurological condition. Patients with hematological malignancies should be monitored closely for IE which is a risk factor for hematogenous spread of brainstem located abscesses.

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Section: Discussionmentioning

confidence: 99%