Acute limb ischemia in a COVID-19 patient

Topcu, Ahmet Can; Aritürk, Cem; Yı́lmaz, Erdal

doi:10.1016/j.tru.2020.100031

Cited by 16 publications

(26 citation statements)

References 13 publications

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“…Notably, while he suffered severe morbidity secondary to limb ischemia, even minor respiratory complications of SARS-CoV-2 were conspicuously absent during his clinical course. This is in contrast with other case reports wherein patients had respiratory symptoms prior to presentation or imaging consistent with respiratory disease burden in conjunction with thromboembolic events (6)(7)(8)(9)(10)(11)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26).…”

Section: Discussioncontrasting

confidence: 98%

Acute limb ischemia and aortic mural thrombosis as primary manifestations of severe acute respiratory syndrome coronavirus 2

Szeles

El-Daher

Lachant

et al. 2021

Journal of Vascular Surgery Cases, Innovations and Techniques

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This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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Section: Discussioncontrasting

confidence: 98%

Acute limb ischemia and aortic mural thrombosis as primary manifestations of severe acute respiratory syndrome coronavirus 2

Szeles

El-Daher

Lachant

et al. 2021

Journal of Vascular Surgery Cases, Innovations and Techniques

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“…The inflammatory cytokines interfere with the coagulation and fibrinolysis processes [8]. Endothelial dysfunction in COVID-19 may be due to the direct entry of SARS-CoV-2 to endothelial cells, causing endotheliitis [9,12]. Some studies have shown the presence of antiphospholipid antibodies, which may cause endothelial dysfunction in COVID-19 patients, who manifested cerebral artery obstruction and limb artery obstruction [9,13].…”

Section: Discussionmentioning

confidence: 99%

Two Different Clinical Presentations of Acute Limb Ischemia Caused by Acute Thrombotic Events in COVID-19

Santosa¹,

Yuwono²

2021

Cureus

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Coronavirus disease 2019 (COVID-19) is a global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coagulopathy is frequently found in severe cases of COVID-19 and is usually manifested as a prothrombotic state. Hyperinflammation, endotheliitis, and immobilization during illness are hypothesized to play a role. Acute limb ischemia (ALI) is one of the presentations of arterial thrombosis in COVID-19. We present two cases of middle-aged men with COVID-19 infection, who developed ALI. The first patient developed ALI after 16 days from the initial COVID-19 diagnosis, and the second patient was admitted to the emergency ward due to sudden discoloration of his right lower limb, and COVID-19 was diagnosed during the evaluation.

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“…In addition to strokes and pulmonary emboli, acute limb ischemia (ALI) secondary to COVID-19 has been described in the literature as early as April 2020. Case reports and studies have demonstrated not only the development of ALI despite prophylactic anticoagulation but also lower rates of successful revascularization [9][10][11]. Generally, and for the exception of graft thrombosis, causes of ALI are either arterial embolism (30-46%) or thrombosis (20-40%).…”

Section: Discussionmentioning

confidence: 99%

Acute Limb Ischemia as the Initial Severe Presentation in COVID-19

Horani¹,

Kaur²,

Patel³

et al. 2021

Cureus

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Coronavirus disease 2019 , caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is characterized by an overwhelming inflammatory response in a subset of patients, resulting in respiratory compromise, multiorgan failure, and death. A common complication seen in patients hospitalized with COVID-19 infections is the development of venous and arterial thromboemboli. This occurs especially in patients who suffer from severe respiratory or systemic manifestations on the COVID-19 spectrum of disease. We present a case of acute limb ischemia as the initial presentation in a patient who tested positive for COVID-19.

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Acute limb ischemia in a COVID-19 patient

Cited by 16 publications

References 13 publications

Acute limb ischemia and aortic mural thrombosis as primary manifestations of severe acute respiratory syndrome coronavirus 2

Acute limb ischemia and aortic mural thrombosis as primary manifestations of severe acute respiratory syndrome coronavirus 2

Two Different Clinical Presentations of Acute Limb Ischemia Caused by Acute Thrombotic Events in COVID-19

Acute Limb Ischemia as the Initial Severe Presentation in COVID-19

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