1985
DOI: 10.1002/jso.2930290102
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Acute leukaemia following malignant ependymoma: A case report

Abstract: Though an increasing number of chemotherapy- and radiotherapy-related leukaemias are being reported, acute promyelocytic leukaemia developing as a therapy-related second malignancy is still uncommon. Here we report a case of acute promyelocytic leukemia, microgranular variant, developing in a case of intracranial malignant ependymoma, 1.5 years following treatment with craniospinal radiotherapy.

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Cited by 7 publications
(1 citation statement)
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“…t-MDS/ t-AML has also been described in individuals exposed to radiation only. 22,30,31 For example, Detourmignies et al described a 12-year-old boy who developed acute promyelocytic leukemia after radiation for cerebral astrocytoma. 32 Risk may be correlated to the volume of exposed marrow.…”
Section: Radiation Therapymentioning
confidence: 99%
“…t-MDS/ t-AML has also been described in individuals exposed to radiation only. 22,30,31 For example, Detourmignies et al described a 12-year-old boy who developed acute promyelocytic leukemia after radiation for cerebral astrocytoma. 32 Risk may be correlated to the volume of exposed marrow.…”
Section: Radiation Therapymentioning
confidence: 99%