Acute Kidney Injury and Advanced Kidney Disease in the COVID-19 Pandemic: Proceedings From a National Kidney Foundation Symposium

Hirsch, Jamie S.; İkizler, T. Alp; Sharma, Shuchita; Mohammed, Azeem

doi:10.1016/j.xkme.2021.03.003

Cited by 6 publications

(9 citation statements)

References 52 publications

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“…We found that by December 2020, almost 700 Medicare bene ciaries who contracted COVID-19 or CLI with no pre-existing ESRD had subsequent kidney transplants, although we could not tell whether the transplants were a direct result of COVID-19. The most common pathology of COVID-19-related AKI is acute tubular injury, however, the direct effect of SARS-CoV-2 infection on renal tissue is unclear (32,33).…”

Section: Discussionmentioning

confidence: 99%

“…Despite the obstacles related to the COVID-19 pandemic, dialysis facilities were able to adjust and provide hemodialysis sessions at average monthly rates of between 2.5 and 2.8 sessions per person per week. However, patients with ESRD and with COVID-19 had remarkably high death rates, underscoring the importance of ongoing efforts to protect at-risk populations from COVID-19, especially considering concerns such as emerging SARS-CoV-2 variants, vaccine effectiveness in persons who are immunocompromised, and waning vaccine immunity over time following vaccination (32).…”

Section: Discussionmentioning

confidence: 99%

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Impact of SARS-CoV-2 on Hemodialysis Among Medicare Beneficiaries in Five Northeastern States, January 2019-December 2020

Andes¹,

Nelson²,

Pavkov³

et al. 2022

Preprint

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Background: The COVID-19 pandemic in the United States is on-going and has impacted healthcare practices substantially. Consistent access to healthcare and, particularly, dialysis services are essential to the management of end stage renal disease (ESRD). The objective of this analysis was to examine patterns of outpatient hemodialysis utilization and outcomes of ESRD and COVID-19 in the 5 states with highest incidence of COVID-19 during the early stages of the pandemic. Methods: We used data from the Centers for Medicare and Medicaid Services (CMS) to examine trends in receipt of outpatient hemodialysis in 2019 and 2020 among Medicare beneficiaries with fee-for-service (FFS) coverage. Results: We found that average monthly hemodialysis rates for beneficiaries with ESRD without COVID-19 were stable over time at average monthly rates of between 2.5 and 2.8 sessions per person per week in both 2019 and 2020. Beneficiaries with COVID-19, both with and without pre-existing ESRD, had hemodialysis rates that varied monthly with an average of 2.5 sessions per week per person. Adjusted death rates were highest among beneficiaries with COVID-19 and pre-existing ESRD, followed by beneficiaries with COVID-19 and no pre-existing ESRD. There was little within-group variation in hemodialysis utilization by race/ethnicity but age- and sex- adjusted death rates varied considerably by racial and ethnic group. Conclusions: Dialysis facilities were able to provide hemodialysis sessions at typical rates despite challenges during the COVID-19 pandemic. However, patients with ESRD who contracted COVID-19 had remarkably high death rates, highlighting the need for ongoing efforts to protect at-risk populations from COVID-19.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Impact of SARS-CoV-2 on Hemodialysis Among Medicare Beneficiaries in Five Northeastern States, January 2019-December 2020

Andes¹,

Nelson²,

Pavkov³

et al. 2022

Preprint

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show abstract

“…Other manifestations can involve other districts. Kidney damage is a frequent complication in hospitalized patients with COVID-19 with an incidence range between 10 and 80% and a significantly increased risk of intra-hospital mortality [ 70 , 71 ]. Neurological symptoms occur most commonly in patients with severe forms of COVID-19 [ 72 , 73 ].…”

Section: Extrapulmonary Manifestations and The Role Of Gut Microbiota...mentioning

confidence: 99%

Microbiological and Clinical Findings of SARS-CoV-2 Infection after 2 Years of Pandemic: From Lung to Gut Microbiota

et al. 2022

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Early recognition and prompt management are crucial for improving survival in COVID-19 patients, and after 2 years of the pandemic, many efforts have been made to obtain an early diagnosis. A key factor is the use of fast microbiological techniques, considering also that COVID-19 patients may show no peculiar signs and symptoms that may differentiate COVID-19 from other infective or non-infective diseases. These techniques were developed to promptly identify SARS-CoV-2 infection and to prevent viral spread and transmission. However, recent data about clinical, radiological and laboratory features of COVID-19 at time of hospitalization could help physicians in early suspicion of SARS-CoV-2 infection and distinguishing it from other etiologies. The knowledge of clinical features and microbiological techniques will be crucial in the next years when the endemic circulation of SARS-CoV-2 will be probably associated with clusters of infection. In this review we provide a state of the art about new advances in microbiological and clinical findings of SARS-CoV-2 infection in hospitalized patients with a focus on pulmonary and extrapulmonary characteristics, including the role of gut microbiota.

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“…Zwischen 30 und 40 % der kritisch erkrankten COVID-19 Patient*innen entwickeln eine akute Nierenschädigung (AKI) [ 24 , 25 ]. Als zugrundeliegende Mechanismen werden neben der COVID-19 assoziierten systemischen Inflammationsreaktion, direkte Endothelschädigungen der Niere angenommen.…”

Section: Nierenersatztherapieunclassified

Update SARS-CoV-2 Behandlungsempfehlungen für die Intensivmedizin

Köstenberger

Hasibeder²,

Dankl³

et al. 2022

Anästhesie Nachr

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Acute Kidney Injury and Advanced Kidney Disease in the COVID-19 Pandemic: Proceedings From a National Kidney Foundation Symposium

Cited by 6 publications

References 52 publications

Impact of SARS-CoV-2 on Hemodialysis Among Medicare Beneficiaries in Five Northeastern States, January 2019-December 2020

Impact of SARS-CoV-2 on Hemodialysis Among Medicare Beneficiaries in Five Northeastern States, January 2019-December 2020

Microbiological and Clinical Findings of SARS-CoV-2 Infection after 2 Years of Pandemic: From Lung to Gut Microbiota

Update SARS-CoV-2 Behandlungsempfehlungen für die Intensivmedizin

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