Acute kidney injury among nonagenarians in Jordan: a retrospective case&amp;ndash;control study

Alshelleh, Sameeha A; Oweis, Ashraf O; Alzoubi, Karem H.

doi:10.2147/ijnrd.s186121

Cited by 9 publications

(6 citation statements)

References 42 publications

(44 reference statements)

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“…8,9 The risk for AKI was shown to be higher among octogenarians and nonagenarians. 10,11 Gender is suggested to increase the risk for AKI regardless of other co-morbidities, where males are at higher risk to get AKI as per Loutradis et al group, 12 In the present study, the number of males with AKI males' number was slightly higher than females. In addition, patients with hypertension were more likely to have AKI than others.…”

Section: Discussionsupporting

confidence: 49%

Acute Kidney Injury Among Patients with Multi-Drug Resistant Infection: A Study from Jordan

Oweis¹,

Zeyad²,

Alshelleh³

et al. 2022

JMDH

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Background: Acute kidney injury (AKI) is a well-known complication for hospitalized patients. Sepsis and various infections play a significant role in increasing the incidence of AKI. The present study evaluated the risk for Multidrug-resistant (MDR) infections and its effect on the incidence of AKI, hospitalization, need for dialysis, and mortality. Methods: In a retrospective study design, data were collected from all adult patients with a positive multi-drug resistant culture who were admitted to King Abdullah University Hospital (KAUH). Records of 436 patients were reviewed between January 2017 -December 2018 with at least one year of follow-up. Results: The mean age was 57.3 years (SD± 23.1), and 58.5% were males. The most common source of positive cultures was sputum, with 50% positive cultures. The incidence of AKI was 59.2%. The most isolated microorganism was Acinetobacter baumannii (76.8%), followed by Pseudomonas aeruginosa (14.9%).On multivariate analysis, age (OR 1.1, 95% CI 1.1-1.2, P=0.001), HTN (OR 1.8, 95% CI 1.0-3.3, P=0.02), DM (OR 1.1, 95% CI 0.6-1.9, P=0.69) and the use of Foley catheter on chronic bases (OR 4.3, 95% CI 2.6-6.8, P<0.0001) were strong predictors of AKI. Among patients with AKI, 74.4% died compared to 44.4% among non-AKI patients (p<0.001). Conclusion:In patients with MDR, AKI incidence, hospitalization, and mortality were high. Early detection and addressing the problem may decrease bad outcomes, and health education for reducing antibiotic abuse is needed to lower MDR.

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Section: Discussionsupporting

confidence: 49%

Acute Kidney Injury Among Patients with Multi-Drug Resistant Infection: A Study from Jordan

Oweis¹,

Zeyad²,

Alshelleh³

et al. 2022

JMDH

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“…This could be related to functional and anatomical changes in the kidney that can happen with aging. 16–18 Different classifications for AKI are used, and incidence can vary based on the system employed. 10 …”

Section: Discussionmentioning

confidence: 99%

Acute Kidney Injury among Hospital-Admitted COVID-19 Patients: A Study from Jordan

Oweis

Alshelleh

Hawasly

et al. 2022

IJGM

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“…In our previous studies involving AKI in elderly patients, we found that age above 60 years will have a higher risk for AKI, morbidity, mortality, length of hospital stay, and need for RRT [ 39 , 40 ]. A recent AKI in ICU epidemiology overview by Santos et al which included data of 67,033 patients from more than 300 ICUs from different regions of the world showed that mortality can range from 5% to 80% (highest) in septic patients, and the need for RRT can range from 0.8% to 59.2% [ 3 ].…”

Section: Discussionmentioning

confidence: 99%

Incidence, Risk Factors, and Outcome of Acute Kidney Injury in the Intensive Care Unit: A Single-Center Study from Jordan

Oweis

Alshelleh

Momany

et al. 2020

Critical Care Research and Practice

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Background. Acute kidney injury (AKI) is a common serious problem affecting critically ill patients in intensive care unit (ICU). It increases their morbidity, mortality, length of ICU stay, and long-term risk of chronic kidney disease (CKD). Methods. A retrospective study was carried out in a tertiary hospital in Jordan. Medical records of patients admitted to the medical ICU between 2013 and 2015 were reviewed. We aimed to identify the incidence, risk factors, and outcomes of AKI. Acute kidney injury network (AKIN) classification was used to define and stage AKI. Results. 2530 patients were admitted to medical ICU, and the incidence of AKI was 31.6%, mainly in stage 1 (59.4%). In multivariate analysis, increasing age (odds ratio (OR) = 1.2 (95% CI 1.1–1.3), P = 0.0001) and higher APACHE II score (OR = 1.5 (95% CI 1.2–1.7), P = 0.001) were predictors of AKI, with 20.4% of patients started on hemodialysis. At the time of discharge, 58% of patients with AKI died compared to 51.3% of patients without AKI (P = 0.05). 88% of patients with AKIN 3 died by the time of discharge compared to patients with AKIN 2 and 1 (75.3% and 61.2% respectively, P = 0.001). Conclusion. AKI is common in ICU patients, and it increases mortality and morbidity. Close attention for earlier detection and addressing risk factors for AKI is needed to decrease incidence, complications, and mortality.

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Acute kidney injury among nonagenarians in Jordan: a retrospective case–control study

Cited by 9 publications

References 42 publications

Acute Kidney Injury Among Patients with Multi-Drug Resistant Infection: A Study from Jordan

Acute Kidney Injury Among Patients with Multi-Drug Resistant Infection: A Study from Jordan

Acute Kidney Injury among Hospital-Admitted COVID-19 Patients: A Study from Jordan

Incidence, Risk Factors, and Outcome of Acute Kidney Injury in the Intensive Care Unit: A Single-Center Study from Jordan

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