Acute kidney injury among hospitalised patients who died due to COVID-19 in the Eastern Cape, South Africa

Abstract

Background: Acute kidney injury (AKI) commonly occurs in coronavirus disease 2019 (COVID-19) patients who have been hospitalised and is associated with a poor prognosis. This study aimed to determine the incidence of AKI among COVID-19 patients who died in a regional hospital in South Africa.Methods: This retrospective record review was conducted at the Mthatha Regional Hospital in South Africa’s Eastern Cape province. Data were collected between 10 July 2020 and 31 January 2021.Results: The incidence of AKI was 38% among the hospitalised patients who died due to COVID-19. Most study participants were female, with a mean age of 63.3 ± 16 years. The most common symptom of COVID-19 at the time of hospitalisation was shortness of breath, followed by fever and cough. Half of the patients had hypertension, while diabetes, human immunodeficiency viruses (HIV) and tuberculosis (TB) were other comorbidities. At admission, the average oxygen saturation was 75.5% ± 17.Conclusion: The study revealed a high incidence of AKI among hospitalised patients who died due to COVID-19. It also found that those received adequate crystalloid fluids at the time of admission had a lower incidence of AKI.Contribution: Acute kidney injury can be prevented by adequate fluid management during early stage of COVID-19. Majority of COVID-19 patients were referred from lower level of care and primary care providers have their first encounter with these patients. Adequate fluid resuscitation in primary care settings can improve the outcome of hospitalised COVID-19 patients.

Burden and risk profile of acute kidney injury in severe COVID-19 pneumonia admissions: a Finding from Jimma University medical center, Ethiopia

“…The magnitude of AKI in our cohort was 42%, which is relatively high compared to other studies that found around 0.5–29% of hospitalized COVID-19 patients developed AKI [ 5 – 7 , 24 ]. However, our estimate is aligned with studies focused only on critically ill patients, of whom 38–45% developed AKI [ 8 , 9 , 11 , 25 ]. The high burden in our study may be attributed to the inclusion of only severe pneumonia cases requiring hospitalization.…”

Perfil da atuação dos Agentes Comunitários de Saúde quanto às sequelas pós COVID-19 em Santarém-PA

“…Fisioterapia Brasil 2023;24(5);605-617 Já após receberam a capacitação, os profissionais destacaram que uma doença renal crônica poderia levar a um quadro mais grave de COVID-19. Vários estudos [16,17] relacionaram também o envolvimento renal na incidência de internações na Unidade de Terapia Intensiva (UTI) e mortes entre pacientes hospitalizados, porém ganharam destaque as lesões agudas, como insuficiência renal aguda e lesão renal aguda [17].…”