Acute Ischaemic Mitral Valve Regurgitation

Hennessey, Breda; Sabatovicz, Nestor; Trigo, María Del

doi:10.3390/jcm11195526

Cited by 5 publications

(3 citation statements)

References 88 publications

(148 reference statements)

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“…In the era of primary PCI, there has been a notable shift in managing IMR, underscoring the importance of early revascularization to mitigate permanent IMR and improve long-term outcomes following acute MI. It is worth noting that a pansystolic murmur in the mitral area, often radiating to the left axillary line, is frequently observed in patients with IMR, highlighting its clinical significance and diagnostic relevance [14].…”

Section: Mechanical Complications 21 Papillary Muscle Rupture and Isc...mentioning

confidence: 98%

Complications in Acute Myocardial Infarction: Navigating Challenges in Diagnosis and Management

Moras,

Yakkali,

Gandhi

et al. 2024

Hearts

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In recent decades, significant advancements in pharmacological, catheter-based, and surgical reperfusion technologies have markedly improved outcomes for individuals undergoing acute myocardial infarction. Despite these remarkable progressions, a segment of patients, particularly those with extensive infarctions or delays in revascularization, remains vulnerable to the onset of mechanical complications associated with myocardial infarction. These complications, spanning mechanical, electrical, ischemic, inflammatory, and thromboembolic events, pose substantial risks of morbidity, mortality, and increased utilization of hospital resources. The management of patients experiencing these complications is intricate, necessitating collaborative efforts among various specialties. Timely identification, accurate diagnosis, hemodynamic stabilization, and decision-making support are crucial for guiding patients and their families in choosing between definitive treatments or palliative care. This review underscores the critical importance of promptly identifying and initiating therapy to reduce prolonged periods of cardiogenic shock and the potential for fatality. By presenting key clinical and diagnostic insights, this review aims to further improve early diagnosis and offer an updated perspective on current management strategies for the diverse range of complications associated with acute myocardial infarction.

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Section: Mechanical Complications 21 Papillary Muscle Rupture and Isc...mentioning

confidence: 98%

Complications in Acute Myocardial Infarction: Navigating Challenges in Diagnosis and Management

Moras,

Yakkali,

Gandhi

et al. 2024

Hearts

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“…PM, the final myocardial segment perfused by coronary blood supply, shows heightened sensitivity to ischemia, with ischemia being the predominant etiological factor contributing to its dysfunction. When ischemic insufficiency affects the PM, patients often manifest a diverse range of clinical phenotypes, ranging from mild MR to potentially life-threatening acute massive MR resulting from PMR [ 21 , 22 ].…”

Section: Pathophysiology Of Papillary Muscle Dysfunctionmentioning

confidence: 99%

“…Once PMR occurs, it leads to the simultaneous prolapse of half of the anterior and posterior leaflets of the mitral valve, causing acute eccentric severe regurgitation. At this point, due to the inability of the left atrium to compensate for the sudden increase in blood volume, acute pulmonary edema may occur, ultimately leading to death [ 22 , 27 , 28 , 29 ].…”

Section: Pathophysiology Of Papillary Muscle Dysfunctionmentioning

confidence: 99%

Left Ventricular Papillary Muscle: Anatomy, Pathophysiology, and Multimodal Evaluation

Li,

Wang,

et al. 2024

Diagnostics

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As an integral part of the mitral valve apparatus, the left ventricle papillary muscle (PM) controls mitral valve closure during systole and participates in the ejection process during left ventricular systole. Mitral regurgitation (MR) is the most immediate and predominant result when the PM is structurally or functionally abnormal. However, dysfunction of the PM is easily underestimated or overlooked in clinical interventions for MR-related diseases. Therefore, adequate recognition of PM dysfunction and PM-derived MR is critical. In this review, we systematically describe the normal anatomical variations in the PM and the pathophysiology of PM dysfunction-related diseases and summarize the commonly used parameters and the advantages and disadvantages of various noninvasive imaging modalities for the structural and functional assessment of the PM.

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Importance of reassessment to identify trajectories of chronic transition of clinical indicators in post-myocardial infarction management

Yoshioka,

Tanaka,

Sonoda

et al. 2024

Cardiovasc Interv and Ther

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Acute Ischaemic Mitral Valve Regurgitation

Cited by 5 publications

References 88 publications

Complications in Acute Myocardial Infarction: Navigating Challenges in Diagnosis and Management

Complications in Acute Myocardial Infarction: Navigating Challenges in Diagnosis and Management

Left Ventricular Papillary Muscle: Anatomy, Pathophysiology, and Multimodal Evaluation

Importance of reassessment to identify trajectories of chronic transition of clinical indicators in post-myocardial infarction management

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