“…In addition, scrotal trauma, insect bites, urine loss to the scrotal area, and cellulitis may be causative factors. Scrotal redness and swelling are the most common clinical signs of AISE, and scrotal pain and tenderness, scrotal, penile, perineal, and inguinal area swelling are often coexistent 8) . Of the patients who are symptomatic, the majority have unilateral involvement, while bilateral involvement is seen in 1/3 of cases.…”