Acute Hyperglycemia an Independent Risk Factor for Contrast-Induced Nephropathy in Patients Undergoing Primary Percutaneous Coronary Intervention for STEMI

Acute Hyperglycemia Facilitates Contrast-Induced Nephropathy: Independent Risk Marker in STEMI Patients Undergoing Primary Percutaneous Coronary Intervention

“…We agree with Khorshid H et al [17] in their assumption that being admission glucose level measurement readily available for all patients presenting with STEMI, this variable could be incorporated into risk calculation models for identification of patients at risk for development of CIN after primary PCI. On the other hand, it is relevant and necessary to further investigate if admission hyperglycemia serves as a risk marker for CIN in patients out of the context of acute coronary syndrome who receive iodinated contrast media during diagnostic coronary angiography.…”

“…On the other hand, procedure-related risk markers for CIN include the use of high-osmolar ionic contrast media, low-osmolar contrast media (compared with nonionic isoosmolar contrast media), high volumes of contrast media, and multiple procedures requiring contrast media within 72 h [3-6]. Percutaneous coronary intervention (PCI) or peripheral artery intervention, coronary artery bypass surgery, and use of an intraaortic balloon pump represent additional procedure-related risk markers [12][13][14][15][16][17][18]. The study of Khorshid H et al [17] in this issue of the Journal of Cardiology and Current Research investigated the association between admission acute hyperglycemia and the risk of subsequent (CIN) in patients with STEMI undergoing primary PCI.…”

“…Overall inhospital mortality of the study population was 10% (n = 6) all of which were in group (A) (P < 0.05). They concluded that in patients undergoing primary PCI, acute hyperglycemia is associated with increased incidence of CIN as well as increased incidence of inhospital adverse events and in-hospital mortality [17].…”

Acute Hyperglycemia Facilitates Contrast-Induced Nephropathy: Independent Risk Marker in STEMI Patients Undergoing Primary Percutaneous Coronary Intervention

“…On the other hand, procedure-related risk markers for CIN include the use of high-osmolar ionic contrast media, low-osmolar contrast media (compared with nonionic isoosmolar contrast media), high volumes of contrast media, and multiple procedures requiring contrast media within 72 h [3][4][5][6]. Percutaneous coronary intervention (PCI) or peripheral artery intervention, coronary artery bypass surgery, and use of an intraaortic balloon pump represent additional procedure-related risk markers [12][13][14][15][16][17][18]. The study of Khorshid H et al [17] in this issue of the Journal of Cardiology and Current Research investigated the association between admission acute hyperglycemia and the risk of subsequent (CIN) in patients with STEMI undergoing primary PCI.…”

“…Percutaneous coronary intervention (PCI) or peripheral artery intervention, coronary artery bypass surgery, and use of an intraaortic balloon pump represent additional procedure-related risk markers [12][13][14][15][16][17][18]. The study of Khorshid H et al [17] in this issue of the Journal of Cardiology and Current Research investigated the association between admission acute hyperglycemia and the risk of subsequent (CIN) in patients with STEMI undergoing primary PCI. The authors studied 120 patients who presented with acute STEMI and were treated with primary PCI.…”