Acute Hydrops in Pellucid Marginal Corneal Degeneration

Carter, John B.; Jones, Dan B.; Wilhelmus, Kirk R.

doi:10.1016/0002-9394(89)90217-1

Cited by 37 publications

(18 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Very few cases of PMCD presenting with hydrops have been reported. Most of such cases had descemet’s break 4 . The present case had descemet’s detachment, which appears to be a result of the distortion of the ectatic cornea.…”

Section: Commentmentioning

confidence: 49%

“…Usually, it is diagnosed between 20 and 40 years of age, occurs in both men and women 2 . PMCD has been reported complicated with hydrops with perforation 3 and due to break or detachment of descemet’s membrane as a result of increasing ectasia 4 . We report such a rare presentation of PMCD with hydrops due to descemet’s detachment without perforation documented by optical coherence tomography (OCT), who was treated by isoexpansile C3F8.…”

mentioning

confidence: 95%

See 1 more Smart Citation

Spontaneneous hydrops in pellucid marginal degeneration: documentation by OCT‐III

Mittal

Rani

Mohan

et al. 2006

Clinical Exper Ophthalmology

View full text Add to dashboard Cite

Corneal pellucid marginal degeneration (PMCD) is an idiopathic condition characterized by non-inflammatory, non-ulcerative thinning of inferior peripheral cornea. PMCD has been reported occasionally complicated with hydrops owing to break in descemet membrane. We herein report a 38-year-old man, who presented with sudden dimness of vision in right eye. Clinical findings and Orbscan II were suggestive of PMCD in both eyes with hydrops in right eye. Slit-lamp and optical coherence tomography of right eye showed central descemet's detachment without any break. Patient underwent descemetopexy by isoexpansile C3F8 (14%) and is doing well with significant improvement in the hydrops.

show abstract

Section: Commentmentioning

confidence: 49%

mentioning

confidence: 95%

Spontaneneous hydrops in pellucid marginal degeneration: documentation by OCT‐III

Mittal

Rani

Mohan

et al. 2006

Clinical Exper Ophthalmology

View full text Add to dashboard Cite

show abstract

“…Although it was initially reported in cases of keratoconus (KC) [1] subsequently it has been seen in other corneal ectasias such as pellucid marginal degeneration (PMD) [2], keratoglobus [3], terrien's marginal degeneration (TMD) [4]. This may also occur in cases of keratectasias after surgery such as following laser-assisted in-situ keratomileusis [5], radial keratotomy [6], deep anterior lamellar keratoplasty (DALK) [7] and penetrating keratoplasty [8,9].…”

Section: Introductionmentioning

confidence: 99%

Management of acute corneal hydrops in ectatic corneal disorders

Sharma

Maharana

Jhanji

et al. 2012

Current Opinion in Ophthalmology

View full text Add to dashboard Cite

The intent of this article is to highlight the various risk factors and the newer diagnostic modalities such as ultra biomicroscopy, anterior segment optical coherence tomography and confocal microscopy in cases of acute corneal hydrops. Further, the conventional as well as the newer treatment modalities are also described. Although newer diagnostic and treatment modalities are found to be useful, the available information in literature is limited. This article will encourage future prospective studies and randomized controlled trials, which may help in finding novel diagnostic and effective therapeutic techniques.

show abstract

“…Acute corneal hydrops is an incompletely understood complication of keratoconus, occurring in approximately three per cent of patients with keratoconus . It may also occur in other corneal ectasias, such as pellucid marginal degeneration and keratoglobus . Corneal hydrops develops following acute rupture of Desçemet's membrane and overlying endothelium that allows aqueous to enter the corneal stroma and epithelium, resulting in severe corneal oedema.…”

mentioning

confidence: 99%

“…1 It may also occur in other corneal ectasias, such as pellucid marginal degeneration and keratoglobus. 2,3 Corneal hydrops develops following acute rupture of Desçemet's membrane and overlying endothelium that allows aqueous to enter the corneal stroma and epithelium, resulting in severe corneal oedema. In recent years, modern technology, such as in vivo confocal microscopy and anterior segment optical coherence tomography, has been able to elegantly demonstrate these features of acute corneal hydrops in vivo.…”

mentioning

confidence: 99%

The Auckland keratoconus study: Identifying predictors of acute corneal hydrops in keratoconus

Gaskin

Good

Jordan

et al. 2013

Clinical and Experimental Optometry

View full text Add to dashboard Cite

Background:The aim was to identify potential factors associated with acute corneal hydrops in a New Zealand population with keratoconus referred to a hospital eye service. Methods: In a single hospital centre, in a retrospective review, demographic and clinical features of subjects with keratoconus and corneal hydrops over a 17-year period were compared with an age-and gender-matched control group of subjects with keratoconus but no history of corneal hydrops. Results: One hundred and one eyes of 101 subjects (mean age 24.6 Ϯ 8.4 years) were identified with keratoconus-related corneal hydrops. Subjects were more likely to be of Pacific but less likely to be of New Zealand European ethnicity than control subjects (n = 101). In comparison, Maori ethnicity was not found to have a significantly positive or negative association with hydrops. The pre-hydrops visual acuity (VA) of affected eyes was poorer than that of controls (p < 0.001) at first presentation to our tertiary referral corneal and contact lens service. Hydrops typically developed approximately four years after diagnosis of keratoconus. Subjects with hydrops were more likely to have a history of eye-rubbing (p = 0.011) but less likely to have a family history of keratoconus (p = 0.05). In 31 cases, the acute hydrops event was their first optometric/ophthalmologic contact. There were no statistically significant differences in the prevalence of atopic disease, contact lens wear or overall corneal transplantation rate between the two groups. Conclusions: Pacific ethnicity, history of eye-rubbing, poor VA at first hospital presentation and lack of family history were statistically associated with developing acute corneal hydrops in keratoconus in a New Zealand population. Greater understanding of such predisposing risk factors may help develop early management strategies to delay or prevent progression of this disease.

show abstract

Acute Hydrops in Pellucid Marginal Corneal Degeneration

Cited by 37 publications

References 12 publications

Spontaneneous hydrops in pellucid marginal degeneration: documentation by OCT‐III

Spontaneneous hydrops in pellucid marginal degeneration: documentation by OCT‐III

Management of acute corneal hydrops in ectatic corneal disorders

The Auckland keratoconus study: Identifying predictors of acute corneal hydrops in keratoconus

Contact Info

Product

Resources

About