Acute hepatobiliary tuberculosis: a report of two cases and a review of the literature

Hickey, Neil; McNulty, James G.; Osborne, H.; Finucane, J

doi:10.1007/s003300050761

Cited by 37 publications

(24 citation statements)

References 11 publications

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“…46 Tuberculosis (TB) may involve the liver in 3 ways: (1) disseminated military TB, (2) primary nodular TB only involving the liver, and (3) primary TB abscess or granulomas of the liver. 47,48 Miliary TB lesions are usually too small to be seen on imaging, but occasionally CT scan will show lowattenuation foci scattered throughout the liver. 49 Ultrasound image may show a pattern of diffuse echogenicity or Bbright liver.…”

Section: Other Infectionsmentioning

confidence: 98%

“…[ 49 In solitary TB hepatic abscess, US image shows a round hypoechoic lesion and CT scan shows a low-attenuation mass. 48 Because imaging findings are nonspecific, diagnosis is made with liver biopsy showing caseating granulomas or acidfast bacilli, positive culture for Mycoplasma or positive polymerase chain reaction. 43 Human immunodeficiency virus infection predisposes patients to opportunistic fungal, viral, protozoan, and mycobacterial infections.…”

Section: Other Infectionsmentioning

confidence: 99%

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Imaging of Hepatic Infections

Benedetti

Desser

Jeffrey

2008

Ultrasound Quarterly

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Hepatic infections include pyogenic and amebic abscesses and fungal and parasitic diseases. Entry of the infectious organisms into the liver can occur by hematogenous spread via the portal vein or hepatic artery, ascension of the infection from the biliary tract, or from trauma. Worldwide, liver abscess is most often caused by Entamoeba histolytica, but in the developed world, pyogenic liver abscess is more common. Fungal infection is most often seen in immunosuppressed chemotherapy patients, whereas parasitic infections are seen in patients with recent travel to endemic areas of Asia, Africa, and South America. Imaging, and in particular ultrasound, plays a crucial role in following patients from treatment to resolution of disease.We review the ultrasound and computed tomographic findings and the clinical features that are characteristic of hepatic pyogenic abscess, amebic abscess, fungal infection, and parasitic infection.

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Section: Other Infectionsmentioning

confidence: 98%

Section: Other Infectionsmentioning

confidence: 99%

Imaging of Hepatic Infections

Benedetti

Desser

Jeffrey

2008

Ultrasound Quarterly

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“…Possible extrapulmonary manifestations of TB are musculoskeletal tuberculosis (spondylitis, tuberculous osteomyelitis, tuberculous arthritis), as well as central nervous system tuberculosis (cranial tuberculous meningitis [14], spinal tuberculous meningitis [15]) and abdominal tuberculosis (gastrointestinal tuberculosis [16], tuberculous peritonitis, hepatosplenic tuberculosis [17], adrenal TB, tuberculous lymphadenitis, and others).…”

Section: Discussionmentioning

confidence: 99%

Intra-abdominal tuberculous peritonitis

Schneider¹,

Ahlhelm²,

Hennes³

et al. 2001

Eur Radiol

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We report the case of a 15-year-old boy suffering from progressive dyspnea on exertion and painful abdominal protrusion. Final diagnosis of intra-abdominal tuberculosis (TB), including lymphadenopathy and abdominal abscess formation, was made following elective laparotomy. This type of disease is a rare manifestation of extrapulmonary tuberculosis. The imaging findings in unenhanced and contrast-enhanced MRI and laparoscopic images are presented. Differential diagnosis of abdominal abscess formation and other fungal or bacteriological infections, as well as the imaging findings of this type of lesion, are discussed. This case demonstrates that atypical manifestation of TB may remain unrecognized; thus, awareness of this kind of manifestation of tuberculosis may prevent patients from being subjected to inappropriate therapies.

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“…Biliary TB is even more uncommon, and no cases of biliary TB causing obstructive jaundice due to biliary stenosis have been reported in Japan. A Pub Med search of papers published after 1985 has yielded 16 reported cases of biliary TB causing obstructive jaundice [2][3][4][5][6][7][8][9][10][11][12][13] (Table 1). In each case, irregular stenosis of one or more bile ducts was seen on ERC, these findings differing considerably from those in cases of TB of the biliary lymph nodes or pancreatic TB, where obstructive jaundice is caused by extramural compression of the common bile duct (CBD).…”

Section: Discussionmentioning

confidence: 99%

Biliary tuberculosis causing cicatricial stenosis after oral anti-tuberculosis therapy

Iwai¹,

Kida²,

Kida³

et al. 2006

WJG

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A 36-ye ar-old P hilippine woman presented wi th dark urine and yellow sclera. Endoscopic retrograde cholangiopancreatography (ERCP) confirmed dilatation of the intrahepatic bile ducts and also showed an irregular stricture of the common hepatic duct at the liver hilum. Histological examination of biopsies from the bile duct revealed epithelioid cell granulomas and caseous necrosis. Tubercle bacilli were then detected on polymerase chain reaction (PCR) testing of the bile, giving the diagnosis of biliary tuberculosis. Although microbiological cure was confirmed, the patient developed cicatricial stenosis of the hepatic duct. She underwent repeated treatments with endoscopic biliary drainage (EBD) tubes and percutaneous transhepatic biliary drainage (PTBD) tubes, and the stenosis was corrected after 6 years. We present a case of tuberculous biliary stricture, a condition that requires careful differentiation from the more common malignancies and needs long-term follow-up due to the risk of posttreatment cicatricial stenosis, although it is rare.

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Acute hepatobiliary tuberculosis: a report of two cases and a review of the literature

Cited by 37 publications

References 11 publications

Imaging of Hepatic Infections

Imaging of Hepatic Infections

Intra-abdominal tuberculous peritonitis

Biliary tuberculosis causing cicatricial stenosis after oral anti-tuberculosis therapy

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