Acute hepatitis due to Mycoplasma pneumoniae infection without lung involvement in adult patients

Romero‐Gómez, Manuel; Otero, M. Ángeles; Sánchez-Muñoz, Diego; Ramírez-Arcos, Mercedes; Larraona, J. L.; García, Emilio Suárez; Vargas-Romero, Julio

doi:10.1016/j.jhep.2005.12.014

Cited by 27 publications

(18 citation statements)

References 8 publications

(7 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…According to those reports, M. pneumoniae -related hepatitis occurs in 2–5% of all M. pneumoniae infection cases [9,10] and 11–50% of M. pneumoniae pneumonia cases [1,3,11,12,13]. The wide range of incidences of M. pneumoniae- related hepatitis reported may be due to the retrospective nature of these previous studies and/or the diverse definitions of hepatitis used in these different studies.…”

Section: Discussionmentioning

confidence: 99%

Clinical Characteristics of Patients with Mycoplasma pneumoniae-Related Acute Hepatitis

Shin¹,

Park²,

Kim³

et al. 2012

Digestion

View full text Add to dashboard Cite

Background/Aims: Although the hepatobiliary manifestations of Mycoplasma pneumoniae infection have been described in several previous studies, controversies still remain. The aim of this study was to evaluate the clinical characteristics of patients with M. pneumoniae-related hepatitis and compare to those with M. pneumoniae infection but not hepatitis. Methods: We reviewed the medical chart of patients diagnosed with M. pneumoniae infection serologically. Results: Among the 117 patients with M. pneumoniae infection enrolled in the study, 25 showed acute hepatitis without any evidence of another cause. Patients with hepatitis presented with prodromal symptoms more frequently and also had a higher body temperature and C-reactive protein (CRP) levels than patients without hepatitis. Frequencies of respiratory tract involvement were not different between two groups. Clinical signs recovered within three weeks in both groups following the institution of antibiotic therapy. Multivariate analysis revealed that male sex, age <40 years, and high CRP levels were significantly linked to M. pneumoniae-related hepatitis. Conclusions: We found that acute hepatitis associated with M. pneumoniae occurred in about 21% of all M. pneumoniae infections, and gender, age, and CRP levels were factors related to the occurrence of M. pneumoniae-related hepatitis.

show abstract

Section: Discussionmentioning

confidence: 99%

Clinical Characteristics of Patients with Mycoplasma pneumoniae-Related Acute Hepatitis

Shin¹,

Park²,

Kim³

et al. 2012

Digestion

View full text Add to dashboard Cite

show abstract

“…Hyperbilirubinemia usually occurs as the indirect type, mostly because of hemolysis in mycoplasma infections. In contrast, adults with M. pneumoniae infection have demonstrated a hepatocellular pattern of liver enzymes without jaundice [14][15][16][17].…”

Section: Pneumoniae-associated Acute Hepatitis Without Pneumoniamentioning

confidence: 97%

“…There is little evidence to indicate direct invasion of M. pneumonia [14]. Few previous liver pathology reports demonstrated non-specific findings, either hepatocellular destruction with inflammatory infiltration or lobular hepatitis [24,25].…”

Section: Diagnosismentioning

confidence: 98%

“…Some bacterial infections are often associated with acute hepatitis, such as Salmonella, Rickettsia, Brucella or M. pneumonia [14]. Hepatitis due to M. pneumoniae was first described in 1975 [15].…”

Section: Pneumoniae-associated Acute Hepatitis Without Pneumoniamentioning

confidence: 99%

“…Hepatitis due to M. pneumoniae was first described in 1975 [15]. Selected cases of M. pneumoniae-associated acute hepatitis were retrieved from MEDLINE and are summarized in Table 1 [9,14,16,17]. In general, acute hepatitis due to M. pneumoniae without lung infection has been largely documented in children with a cholesteric pattern [9,10].…”

Section: Pneumoniae-associated Acute Hepatitis Without Pneumoniamentioning

confidence: 99%

See 2 more Smart Citations

Review Article: Mycoplasma Pneumoniae-Associated Acute Hepatitis

Lee¹

2017

GHOA

View full text Add to dashboard Cite

Mycoplasma pneumoniae is a major cause of respiratory infections and a possible etiology of acute hepatitis. Acute hepatitis due to M. pneumoniae infection is often combined with presentation of pneumonia, even without lung involvement. The presentations and etiologies of M. pneumoniae-associated hepatitis with simultaneous, delayed, or without, lung involvement are different, and should be discussed separately. The most widely available and effective drug of treatment is macrolides, and its clinical outcome is extremely good.

show abstract

Bacterial, Rickettsial and Spirochaetal Infections

Sánchez-Tapias¹

2007

Textbook of Hepatology

View full text Add to dashboard Cite

Acute hepatitis due to Mycoplasma pneumoniae infection without lung involvement in adult patients

Cited by 27 publications

References 8 publications

Clinical Characteristics of Patients with Mycoplasma pneumoniae-Related Acute Hepatitis

Clinical Characteristics of Patients with Mycoplasma pneumoniae-Related Acute Hepatitis

Review Article: Mycoplasma Pneumoniae-Associated Acute Hepatitis

Bacterial, Rickettsial and Spirochaetal Infections

Contact Info

Product

Resources

About