“…Since that time, continued reports speak to the risk of increased blood pressure with PPA (Bradley, 1991;Morgan & Funderburk, 1992;Onuigbo & Alikhan, 1998). Other adverse events have been reported including cerebral arteritis (Ryu & Lin, 1995), cardiac arrhythmias (Onuigbo & Alikhan, 1998), the exacerbation of psychosis Chromium picolinate Hypoglycemia, nephrotoxicity, rhabdomyolysis, acute generalized exanthematous pustulosis, cognitive and personality disturbance Crone & Wise, 2000a;Bunner & McGinnis, 1998;Wasser et al, 1997;Cerulli et al, 1998;Michenfelder & Thompson, 1997;Martin & Fuller, 1998;Young et al, 1999;Huszonek, 1993 Echinacea Avoid use with systemic illnesses such as tuberculosis, leukoses, collagen diseases, and multiple sclerosis; limit use to less than 8 successive weeks; these recommendations have more recently been questioned Robbers & Tyler, 1999a;Blumenthal et al, 2000a Ephedrine (Ma Huang) Sudden death (myocardial infarction), hemorrhagic and ischemic stroke, acute hepatitis, nephrolithiasis, dizziness, tachycardia, headache, tremor, nervousness, insomnia Haller & Benowitz, 2000;Anonymous, 1996;Tyler, 1996;Theoharides, 1997;Nadir et al, 1996;Powell et al, 1998;Astrup et al, 1992 Fenugreek Mild hypoglycemic effect Mishinsky et al, 1967 (Continued) Gingko biloba Headache, GI upset, allergic skin reactions, cerebral hemorrhage, interaction with platelet antiaggregating, and thrombolytic therapy Kleijnen & Knipschild, 1992;Rosenblatt & Mindel, 1997;Rowin & Lewis, 1996;Gilbert, 1997;Vale, 1998 Ginseng, Korean See Ginseng, Panax Ginseng, Panax Nervousness, insomnia, nausea, headache, diffuse mammary nodularity, vaginal bleeding, mania Gabel, 1998a;…”