Acute Follicular Graft-versus-Host Disease

Tani, Masahiro; Adachi, Akihiko

doi:10.1159/000247469

Cited by 11 publications

(4 citation statements)

References 6 publications

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“…In the literature, acute follicular GVHD is reported to be frequent and to begin in earlier phases (24,25). In one of our patients, perifollicular papular lesions were the first and the only lesions of acute GVHD.…”

Section: Discussionmentioning

confidence: 50%

Clinical Manifestations of Cutaneous Graft-versus-host Disease after Allogeneic Haematopoietic Cell Transplantation: Long-term Follow-up Results in a Single Turkish Centre

Şanlı¹,

Ekmekçı²,

Arat³

et al. 2004

Acta Dermato-Venereologica

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The aim of this study was to evaluate the clinical manifestations of cutaneous graft-versus-host disease (GVHD) developed after allogeneic haematopoietic cell transplantation. In all, 67 patients were evaluated: 49 patients developed acute GVHD, 17 patients developed de novo chronic GVHD and 29 developed secondary chronic (15 limited, 14 progressive) GVHD following acute cutaneous GVHD. Of the 46 patients with chronic GVHD, lichenoid lesions were observed in 32 and sclerodermoid lesions were observed in 12. In four patients with sclerodermoid cutaneous GVHD, these lesions occurred after a lichenoid phase. Oral lesions were present in 61% of the patients and six of them had only oral mucosal involvement without any skin lesions. Nail lesions were observed in 31% of the patients. During the follow-up period 15 patients with GVHD died and in 7 of them the cause of death was related to chronic GVHD. In conclusion, GVHD has a wide spectrum of cutaneous manifestations, which can be used as an important tool for the early diagnosis of the disease.

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Section: Discussionmentioning

confidence: 50%

Clinical Manifestations of Cutaneous Graft-versus-host Disease after Allogeneic Haematopoietic Cell Transplantation: Long-term Follow-up Results in a Single Turkish Centre

Şanlı¹,

Ekmekçı²,

Arat³

et al. 2004

Acta Dermato-Venereologica

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“…Chronic GVHD is generally treated with a combination of corticosteroids and cyclosporine or corticosteroids and azathioprine. [41][42][43][44] Chronic GVHD can be histologically indistinguishable from LP. 45 …”

Section: Pathogenesismentioning

confidence: 99%

Lichenoid eruptions in children

Tilly

Drolet

Esterly

2004

Journal of the American Academy of Dermatology

113

118

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“…The appearance of follicular papules post bone marrow transplantation is a matter of concern as this could be a presentation of acute follicular graft-versus-host disease (GVHD). [ 1 ] However, a few mimics should be borne in mind while addressing such cases and dermoscopy offers the advantage of arriving at the diagnosis in certain instances. [ 2 ] Here, we report a 9-year-old child with chronic myeloid leukemia (CML) post non-myeloablative allogeneic hematopoietic stem cell transplantation (HSCT), who developed a pruritic follicular rash all over the body.…”

mentioning

confidence: 99%

“…Their appearance in the setting of post bone marrow transplantation could be a harbinger of sinister conditions like acute GVHD or disseminated fungal infections. [ 1 ] In most of the instances, histopathology gives a clue to the diagnosis. However, dermoscopy is a noninvasive diagnostic tool which can help in an earlier diagnosis of follicular lesions as in our case.…”

mentioning

confidence: 99%